The power of one: A simpler, cheaper method for cell fusion
... once, it may be expanded so that multiple devices simultaneously fuse cells in parallel. "In time, this could drastically increase the rate of cell fusion," he said. Lu has shown that his technology has a success rate comparable to current technology; about 30 percent to 40 percent of the cells are properly ...NHGRI aims to make DNA sequencing faster, more cost effective
...hrough this program in which a nanopore is used to simultaneously detect electrical and fluorescent signals from many nanopores at one time. A novel sequencing instrument will be fabricated, along with additional analysis tools, with the aim of producing a viable, low-cost sequencing system. Timothy D. Harris, P...Male contraception: One door opens, another closes
...nownst to Amory, pharmaceutical giant Schering was simultaneously testing miglustat in rabbits and another strain of mice, and found the same results--contraception in the first strain of mice, but no effect in the other strain or other species. The original studies used C57 Black/6 mice, the most common strain ...Why do cold animals make bigger babies?
...duce in the cold. When they tested the theories simultaneously with their new approach, the team concluded that temperature's effect on reproduction is a byproduct of its effect on adult size. "This result could have widespread significance," says Angilletta. "Temperature determines the adult size of virtually a...Encouraging results in pancreatic cancer research
...riod in the peritoneal cavities of mice containing simultaneously transplanted tumors, PNC-28 caused complete destruction of these tumors. When delivered concurrently with tumor implantation, PNC-28 completely blocked tumor growth during the two-week period of administration and two weeks post-treatment, followe...New UD technology removes viruses from drinking water
...enge facing the water treatment industry is how to simultaneously control microbial pathogens, disinfectants such as chlorine, and toxic disinfection byproducts in our drinking water, and at an acceptable cost," Chiu noted. Viruses are difficult to eliminate in drinking water using current methods because they a...Reminding doctors which antibiotics to prescribe cuts C. difficile infection rates
...ocomial infection) statement---are being published simultaneously in The Lancet Infectious Diseases this month and also the Journal of Antimicrobial Chemotherapy.4 This statement, put together with the aim of improving the quality of research in hospital epidemiology to ensure it is robust enough to influence polic...Moonlighting enzyme linked to neurodegenerative disease
...nized mechanism by which certain DLD mutations can simultaneously induce the loss of a primary metabolic activity and the gain of a moonlighting proteolytic (breaking down enzymes) activity. The latter could contribute to the metabolic derangement associated with DLD deficiency and represent a target for therapies ......activity was enhanced when the video was presented simultaneously with the sound. "This finding suggests that sensory integration, which is so fundamental to complex mental activity, takes place at very early processing stages," says Daniel Tranel, PhD, of the University of Iowa, who is not affiliated with the ...Neural bottleneck found that thwarts multi-tasking
...cond task when the two tasks were presented nearly simultaneously ?within 300 milliseconds of each other," Marois said. "If individuals have a second or more between tasks, we did not see this delay. "This temporal delay is the essence of dual-task interference for tasks that require actions. By using time-resol...Researchers discover new details about HIV-1 entry and infection
...sure to HIV-1. The researchers found that HIV-1 simultaneously enters two different types of intraepithelial cells associated with the immune system, Langerhans cells (LC) and CD4+ T cells. However, the path of entry and fate of infection was different for the two cell types. Infection of CD4+ T cells appears to...Scientists create dual-modality microbeads to improve identification of disease biomarkers
...beads. The researchers developed a technique to simultaneously or sequentially add optical and magnetic nanoparti...ic nanocrystals are added to the suspension either simultaneously or sequentially. __IMAGE_3 After 15-20 minutes, the butanol is removed to get rid of any remai...Proteins important in Alzheimer's, Parkinson's disease travel in the slow lane
...n directly visualized." Roy devised a system to simultaneously visualize the transport of two labeled slow-component-b proteins in living cultured mouse axons. This clarified unique aspects of slow-protein transport. He found that the "slow" proteins actually showed rapid bursts of movement followed by pauses. T...New study may show how to forestall a fatal, virus-caused immune-system meltdown
...k. He said that checking almost 1,200 interactions simultaneously let the researchers see the big picture of immune response, avoiding the contradictory results often produced by studies that focus on only a single biochemical pathway. To better understand their results, the investigators plugged their data in...Stability of mRNA/DNA and DNA/DNA duplexes modulates mRNA transcription
...t is amazing that the same nucleotide sequence can simultaneously encode its respective protein and modulate its level of expression." says Stoynov. The mechanism of how DNA/DNA and mRNA/DNA duplex stability influences mRNA level remains unclear. The authors propose two models, but further work is needed to under...Ebola outbreaks killing thousands of gorillas and chimpanzees
...ubsequent group. Chimpanzees and gorillas also fed simultaneously in the same fruit tree at least once every seven days. The study also provided the first evidence that gorillas from one social group closely inspect the carcasses of gorillas from other groups. Contact with corpses at funerals is a major mechani...Shedding new light on proteorhodopsin
...s to fossil fuel energy sources. Microbes that can simultaneously harvest energy from several different sources may be better at producing biofuels than microbes that can only utilize a single energy source. The results of this study appear in a paper published by the Proceedings of the National Academy of Scie...NASA predicts nongreen plants on other planets
...ed on Earth-like planets around other stars, while simultaneously improving our understanding of life on Earth," said Carl Pilcher, director of the NAI at NASA Ames. "This approach -- studying Earth life to guide our search for life on other worlds -- is the essence of astrobiology." Kiang and her colleagues cal...A genetic 'gang of 4' drives spread of breast cancer
...rowth and spread of human breast tumors in mice by simultaneously targeting two of the proteins produced by these genes, using drugs already on the market. The researchers are exploring clinical testing of combination therapy with the drugs—cetuximab (trade name Erbitux) and celecoxib (Celebrex)—to treat breast can......that electronic tracking devices have been applied simultaneously to deep-diving predators and prey in the same wate...ng. To our knowledge, this is the first attempt to simultaneously study a mesopelagic predator and its prey using electronic tagging techniques." Size matters ...