Aptamer-based Biosensor screens Air Force personnel and equipment
...mplementary to the Air Force's technology and that simultaneously satis? es the speed, specificity, sensitivity, portability, durability, health and safety needs," said Mike Lind, a senior advisor at PNNL. "The rapid detection capability of this instrument will be useful in a variety of applications, even outside o...Microscopic brain imaging in the palm of your hand
...t are much less likely to absorb a pair of photons simultaneously and fluoresce in response. While two-photon microscopy offers an alternative to traditional one-photon fluorescence microscopy, it still only penetrates brain tissue down to about 500-600 microns ?barely scratching the surface. To get at the deep s...Divergent life history shapes gene expression in brains of salmon
...etts, with new functional genomics technologies to simultaneously monitor thousands of genes in individual tissues. "Research like this was very difficult in the past because we lacked adequate tools to measure gene expression," Aubin-Horth says. "As a result almost nothing is known about the molecular basis of de...Secrets to antibody's success against West Nile Virus surprise scientists
...n in macrophages even worked when the virions were simultaneously exposed to antibodies known to enhance infection. "Do the therapeutic antibodies also prevent the virus from properly injecting its genetic material into macrophages? It's a tempting possibility, but we don't have the evidence to prove it yet," he...Quantum dots provide a faster, more sensitive method for detecting respiratory viral infections
...ll be to develop a quantum dot cocktail capable of simultaneously detecting the presence of at least five major respiratory viruses: influenza A and B, parainfluenza and metapneumovirus, in addition to RSV. This should be fairly straightforward, Wright says. In the current paper, Wright and Crowe demonstrate that t...Past droughts geographically widespread in the West, according to tree-ring data
...s, either low flows or high flows, tended to occur simultaneously in the Upper Colorado and Salt/Verde river basins; Such synchronous low-flow and high-flow events tended to cluster in time; The longest continuous period when both basins had extreme low-flow years was three years; Within any fo...Researchers identify genes associated with lung transplant rejection
...hey were able to look at hundreds of gene products simultaneously in lung tissue samples only a few millimeters across. "That was our first achievement: being able to accurately measure that many genes in small samples," notes Caughey, who is also a professor of medicine at UCSF. "We succeeded way beyond our expect...Huntington's cure in flies lays groundwork for broader treatment approaches
..., Yin believes a promising alternative might be to simultaneously target a cocktail of gene-induced activities - all of which are set in motion, for example, by a single faulty gene. Yin has long worked in the area of "triplet expansion" diseases such as Huntington's and Fragile X, in which genes go haywire due to...Nanoscale method for investigating living systems
...ane pores in order to visualize their function and simultaneously measure their current/voltage relationship. "What we found was that quantum dots formed their own pores, which in the long run could mean that we could combine optical activity and readout with direct-current recording of cellular activity," says Bli...Mosquito study shows new, faster way West Nile can spread
... that when infected and uninfected mosquitoes feed simultaneously on previously uninfected laboratory mice, the virus can pass from mosquito to mosquito within an hour. "We were amazed to see that it could happen," said UTMB associate professor Stephen Higgs, lead author of a paper on the discovery that will be pu...Stem cells bring fast direct improvement, without differentiation, in acute renal failure
...mplicated by the fact that patients with ARF often simultaneously suffer failure of other major organ systems. The most serious form of ARF is caused by ischemia, or loss of blood supply to the kidneys caused by shock, blood infection or major cardiovascular surgery, particularly in such high- risk patients as tho...Clearing jams in copy machinery
...gues show that, because both polymerases are bound simultaneously to the beta clamp, it can pull either of the polymerases out if its toolbelt as needed. O'Donnell and his colleagues propose two explanations for how the polymerase switch is controlled. "One possibility is that the beta clamp may sense when Pol II...Scientists create digital bacteria to forge advances in biomedical research
... the level of bacterial populations. AgentCell can simultaneously simulate activity on all three scales, something its creators believe no other software can do. "With AgentCell we can simulate the behavior of entire populations of cells as they sense their environment, respond to stimuli and move in a three-dimen...Baby's genes affect mom's cholesterol levels
...others may lower these levels when it is expressed simultaneously by the fetus in the placenta. These findings have implications for many women who are advised not to have children due to genetic defects in lipoprotein metabolism. Because their fetuses can compensate for their defects, the women may actually be ab...Preventing a pandemic: Study suggests strategies for containing a flu outbreak
...ther group of MIDAS researchers is being published simultaneously in the journal Nature. ...UQ scientists break new ground in fight against infection & chronic disease
...le to show, for the first time, both actions occur simultaneously and a common cellular pathway is used for releasing messengers and for eating microbes," she said. "This adaptation ensures the whole immune system responds to an infection in the most efficient and rapid way possible. "In some situations, this c...Agricultural workers at increased risk for infection with animal flu viruses
...i, M.D. "The worry is that if a pig were to become simultaneously infected with both a human and an avian influenza virus, genes from these viruses could reassemble into a new virus that could be transmitted to and cause disease in people." The study results strongly suggest that occupational exposure to pigs sig...Customized gene chip provides rapid detection of genetic changes in children's cancer
...aid Dr. Fortina. He noted that the researchers can simultaneously evaluate seven chromosomal regions known to be involved in neuroblastoma. Unlike gene expression microarrays, which detect varying levels of RNA to measure the activity levels of different genes as DNA transfers information to RNA, the current micro......"There is currently a critical need for methods to simultaneously image the activity of multiple proteases in vivo," said Drezek. "This is important not only for early detection of several diseases, but perhaps more significantly, in understanding and monitoring the efficacy of therapeutic interventions, including ......n a myriad of disorders, including epilepsy. They simultaneously measured activity in both a specific type of inhibitory neuron, called fast-spiking, and a neighboring excitatory neuron. They then stimulated one or the other neuron and measured responses in the second neuron. They found that connections from the f...