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Tag: "simulation" at biology news

Cellular message movement captured on video

...e they passed fluid across the cells’ surface in a simulation of flowing blood. With that physical stimulus, paxillin consistently moved in the same direction as the fluid flow. Paxillin is found primarily at focal adhesions, busy intersections of activity scattered around the cell’s cytoplasmic membrane. Fo...

Simulations unravel outer membrane transport mechanism

...n Stauffer Using X-ray data and advanced computer simulation and visualization software, researchers at the Uni...eation pathway through the barrel" In the first simulation the researchers applied a force to TonB and showed that the multiple hydrogen bonds between TonB and...

Helping chlorine-eating bacteria clean up toxic waste

...rk Sciences (GNS), a firm specializing in computer simulation of biochemical processes, to create computer models of the inner workings of the bacterium. The project is funded by a three-year, $381,000 grant from the Department of Defense, which has some 6,000 toxic-dump sites of its own to clean up. Richard...

Prehistoric origins of stomach ulcers uncovered

...ts combined their genetic analysis with a computer simulation the modelled the spread of the bacteria across the globe. This showed that it migrated from Eastern Africa at almost exactly the same time as early humans, approximately 60,000 years ago. The UK research effort was led by Dr Francois Balloux, a B...

How to manage forests in hurricane impact zones

...ndations for different situations. "Our simple simulation of stem breakage potential suggests that stand spacing and tree height can be manipulated to reduce risk, and provides a start for managing forests for hurricane risk," says Stanturf. "Additional research is needed on the effects on vulnerability of ...

Meeting the ethanol challenge: Scientists use supercomputer to target cellulose bottleneck

...e into sugar molecules. To the scientists, the simulation is like a stop-motion film of a baseball pitcher throwing a curveball. In real-life the process occurs far too quickly to evaluate visually, but by using the supercomputer simulations to break the throw down into a step-by-step process, the scientist...

Supercomputing equipment to advance the frontiers of computational biology

...nt, while also supporting a project to develop new simulation technologies for understanding biological systems....es a more quantitative field, researchers need new simulation technologies to understand how proteins, DNA, and other biological systems behave at the molecular l...

Researchers make nanosheets that mimic protein formation

...missing, the sheets would not form, confirming the simulation predictions. "Self-assembly is nature's basic building principle for producing organized arrays of biomolecules with controlled geometrical and physicochemical surface properties," Glotzer said. "In the fabrication of functional nanoscale materia...

New study calculates millions of years saved in lives of AIDS patients

...atient survival, the investigators used a computer simulation model to examine national surveillance and efficac... specific advances in AIDS care, and then used the simulation model to determine per-person survival time for each era, compared to the absence of treatment. The...

Gene therapy injected into the brains' of mice with Huntington's disease

...mice also showed diminished hind limb clasping, (a simulation of motor control behavior in HD patients). Perhaps most importantly, gene delivery of GDNF provided neuroprotection in the brain, with reduced density of brain inclusions and less cell death. The authors wrote "Although GDNF's exact role in prevent...

Viagra improves high altitude exercise performance up to 45% for some

...denafil doses, 50 mg or 100 mg. The high altitude simulation was achieved by changing the mix of air. The cycli...se session and continuing through the session. The simulation did not include the lower air pressure that would occur at altitude, Friedlander said. Researchers ...

Avian flu modeled on supercomputer, explores vaccine and isolation options for thwarting a pandemic

...onal health emergency, scientists have developed a simulation model that makes stark predictions about the possi...nt issue of April 11. The large-scale, stochastic simulation model examines the nationwide spread of a pandemic influenza virus strain, such as an evolved avian ...

Major WHO study concludes calcium supplements can reduce complications during pregnancy

...nt double-mutant strain. Perryman used a computer simulation program called AMBER that performs several different types of calculations. The x-ray crystal structure of the molecule is used as the input, and the various motions and shapes sampled are governed by Newtonian physics, the electric forces among atom...

Computer simulation hints at new HIV drug target

...nt double-mutant strain. Perryman used a computer simulation program called AMBER that performs several different types of calculations. The x-ray crystal structure of the molecule is used as the input, and the various motions and shapes sampled are governed by Newtonian physics, the electric forces among atom...

Pleasing plant shapes explained by new computer model

... an animated model that provides the most detailed simulation of how plants grow into recognizable shapes. In t...nists in Switzerland to create a three-dimensional simulation of plant growth at the microscopic scale, simulating cell division and showing how concentrations of...

'Computer-chemistry' yields new insight into a puzzle of cell division

...hemical studies, but also from using sophisticated simulation techniques to perform "chemistry in the computer." In a paper published Nov. 24, 2005 online in the journal Biochemistry, members of the interdisciplinary collaboration described how they discovered the probable orientation required for a Cdc25B pho...

Free-energy theory borne out in large-scale protein folding

... and quantitative comparison of the time-dependent simulation data with the experimental measurements from circu...omy, who helped the team analyze and interpret the simulation data. ...

Grid bridges 4,800 miles for molecular repositories

...igabytes to terabytes. The extreme file sizes mean simulation data generally resides in the home laboratory wher...naccessible to other research groups. Yet sharing simulation data for comparative analysis is a major goal of biomolecular scientists whose work aims to solve pr...

Wright bros. upstaged! Dinos invented biplanes

...plin fed Microraptor's flight data into a computer simulation that they have previously used to successfully analyze the flying abilities of pterosaurs and Archaeopteryx. Based on the aeronautical analysis, it appears that Microraptor flights looked rather like those seen today among some "monoplane" forest bir...

Solution to 'legionella'

...ET-Tecnalia experts designed a refrigeration tower simulation within a biologically-isolated laboratory (P2 level). A wide range of trials were carried out in this isolated and secure system in order to determine the efficacy thereof. Regarding the technology developed, it consists of a system based on low-int...

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