Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance
...atient survival once metastasis has occurred." To simulate the environment in which melanoma naturally arises, the research team introduced one or more cancer-associated genes into human melanocytes, the pigment-producing cells that normally reside in the deepest layer of the skin. The genetically engineered......atient survival once metastasis has occurred." To simulate the environment in which melanoma naturally arises, the research team introduced one or more cancer-associated genes into human melanocytes, the pigment-producing cells that normally reside in the deepest layer of the skin. The genetically engineered...Engineered skin offers clues to melanoma development
...atient survival once metastasis has occurred." To simulate the environment in which melanoma naturally arises, the research team introduced one or more cancer-associated genes into human melanocytes, the pigment-producing cells that normally reside in the deepest layer of the skin. The genetically engineered...UNC computer, marine scientists collaborate to predict flow of toxic waters from Katrina
...sor of marine sciences, respectively, knew that to simulate the required 60 days of water velocity and water s...ing model used by the National Weather Service, to simulate wind speed, direction and other weather factors. Their goal is to provide daily forecasts of coastal...Woods Hole Research Center plans controlled burn in Amazon rainforest
... will be burned for the first of several times, to simulate the repeated impacts of escaped agricultural fires that burn through the understory of frontier forests every dry season. These areas are already slated for destruction to expand soy fields. The planned burn provides information that cannot be obtai...Female volunteers prepare for a second 'bedrest'
...completed 60 days of voluntary bedrest in order to simulate the physiological effects of weightlessness on the human body. The research team in Toulouse, France, is now actively seeking twelve new volunteers to enable them to continue and enhance the research. At the beginning of June, the twelve volunteers ...Assessing the Amazon River's sensitivity to deforestation
...and the River system. So this model, by letting us simulate the entire river through time, has helped us learn much about how the river flow and flooded area react to year-to-year variations in climate." Currently entering a third phase of study, a model of the Amazon River and floodplain will be combined wi...No relief for Pacific Northwest drought
...llowing years if drought resumes. The models that simulate the droughts and the likelihood of fire are complex and sometimes counter-intuitive, the researchers said, involving such things as vegetation growth, fuel loads, soil moisture, climatic trends and other factors. "Last year was a pretty severe droug...Chemists identify immune system mechanism for methamphetamine binges
...eviewed journal. In a test tube study designed to simulate the chemical reactions that occur with the drug when it enters the bloodstream, the researchers showed that methamphetamine reacts with glucose and proteins to form a larger-size "glycated" product. This product is then recognized by immune system co...Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits
...ts would make such a model possible. "We'd like to simulate diseased cell types, such as cancer cells, and then simulate the effects of drugs on those diseased cells," said Ideker. "Ultimately, we think this kind of a sys...Poplar trees redirect resources in response to simulated attack
...at Brookhaven, we now have a way to find out." To simulate an insect attack, the scientists painted a solution of jasmonic acid, a chemical messenger that plants produce in response to various types of stress, onto the leaves of poplar trees in a closed chamber. They then administered carbon dioxide gas "lab...