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Tag: "similarity" at biology news

Scientists find missing enzyme for tuberculosis iron scavenging pathway

... antibiotic resistance genes due to their sequence similarity to existing antibiotic resistance genes. Dr. Edward N. Baker of the University of Auckland in New Zealand explains, "Generally the sequence of the open reading frame is compared with the sequences of genes for other proteins (most of which are from d...

Found: Missing sequence of the human Y chromosome

..., 4,9, 10, 11, 14, 15, 16, and 22. This remarkable similarity can beattributed to segmental duplications, a phenomenon whereby largeportions of the genome are copied during evolution. Segmentalduplications, which emerged during the past 30 million years of primateevolution, are significantly enriched in subtelo...

Same mutation aided evolution in many fish species, Stanford study finds

...in how a gene was turned on and off. The striking similarity is that in both studies evolution turned to the same genetic switch to work a visible change in the fish. However, in the fin study the group wasn't able to pinpoint the exact genetic alteration. The group continues to wade out into nature, collecti...

Scientists reveal molecular secrets of the malaria parasite

...n able to generate maps thatcompare the degrees of similarity among genes on P. falciparumchromosomes and its rodent-malaria counterparts."The paper is significant on many levels, including the integration ofdraft genome sequence data with microarray and protein expressiondata," says Carlton. "This project also...

TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas

...d's group previously identified TEL2 and noted its similarity to TEL1, which prompted them to investigate whether TEL2 also played a role in leukemia. In the MCB study, the investigators discovered that, unlike TEL1, TEL2 promotes cell multiplication, playing an indirect role in the development of B lymphoma. ...

Genrate: a generative model that finds and scores new genes and exons in genomic microarray data

...eshold-based decisions on intensity of expression, similarity of expression profiles, and arrangements of exons in the genome. We have taken a Bayesian approach and developed GenRate, a generative model that accounts for both genome-wide expression data taken from multiple conditions (e.g. tissues) and co-loca...

Great White shark evolution debate involves WSU Lake Campus geology professor

... the root and entire tooth also shows a remarkable similarity in all four tooth positions under study for both t...d mako shark. Serration densities possess a strong similarity between the Great White and makos, where the serration densities between the Great White and meglado...

Fleshing out the genome

...iological function and ranking them based on their similarity to genes known to encode proteins. Proteins are the workhorses of the cell, playing a role in everything from energy transport and metabolism to cellular communication. This new ability to rank hypothetical sequences according to their likelihood to...

No relief for Pacific Northwest drought

...on is going to go from bad to worse. It bears some similarity to conditions last seen in 2001. "We use five different global climate models as the underlying basis for our projections, and they are all showing the same thing," Neilson said. "It is going to become extremely dry in many parts of the Pacific Nort...

Marburg haemorrhagic fever in Angola update

...ficult: the extreme rarity of this disease and its similarity to other diseases seen in countries where deaths from infectious diseases are common. Neither the source nor the date of the initial cases in Angola can be presently identified with any certainty. The number of cases began increasing in February and...

Molecular thermometers on skin cells detect heat and camphor

...-assembled draft of the human genome. Its sequence similarity to other temperature-gated proteins led them to identify and clone TRPV3 as a possible molecular thermometer--perhaps the first one that makes skin cells able to sense warm temperatures. Now they have demonstrated that the receptor does indeed detec...

Venom doc tracks down snake bioweapons

... (called the waglerin peptide) did not exhibit any similarity to known proteins. Fry believes that it may be a reptile-specific protein. "The wide-ranging origins of snake venom toxin - body counterparts explain the amazing diversity of ways that venomous snakes can kill their prey and why they have so much po...

Leprosy genome tells story of human migrations, French researchers report in Science

...these possible combinations. Overall, the genetic similarity between the different samples suggests that the bacterium's genome is exceedingly stable. "It seems that there was only a single source of the bacterium that was at the origin of this global pandemic," Cole said. Each of the four SNP combinations w...

Spiders help scientists discover how muscles relax

...cture of the smooth muscle myosin molecules. The similarity suggests, Padron said, that the interacting head structure may be common to relaxed-state myosin for smooth and striated muscle and among varied species. "This model is applicable across the whole animal kingdom and all muscle types, and that's excit...

'Punctuated' evolution in the human genome

... which are large DNA sequences that exhibit strong similarity to the euchromatic ancestral loci from which they were copied. According to Eichler, the limited number of comparisons of pericentromeric regions among closely related primates suggests extraordinary dynamism, where duplication, deletion, and rearran...

Gap-climbing fruit flies reveal components of goal-driven behaviors

...the motor programs employed by the flies show high similarity to vertebrate motor programs--for example, when a person is trying to reach a jar on a shelf high above her head, she will reach out with her arm and hand, will straighten her back, and tiptoe. Studying the underlying control principles and neuronal...

Results of world's first gene therapy trial for arthritis show approach safe, feasible

...a, the researchers point out that this is the only similarity between the two trials. The studies were concerned with different genes and with different targets, and in the arthritis trial, the transduced cells were removed after one week during routine joint replacement surgery. Nonetheless, with safety a key ...

DNA traces evolution of extinct sabertooths and the American cheetah-like cat

...ged nares, but the genetic data indicate that this similarity is in fact a marvellous example of evolutionary parallelism, the development of similar body plans in response to similar ecological pressures. In light of the new DNA data and fossil information from other studies, it appears likely that a puma-like...

Studies on human genome variation provide insight into disease

...te cancer susceptibility. "Because of the strong similarity among genes in this region, we had to develop a new technique for our mutational analysis, which we call TAR cloning," explains Larionov. "Using this method, we isolated the SPANX region from 200 individuals by recombination in yeast." Based on...

Housecat-sized Siberian tiger cubs get collared

...te cancer susceptibility. "Because of the strong similarity among genes in this region, we had to develop a new technique for our mutational analysis, which we call TAR cloning," explains Larionov. "Using this method, we isolated the SPANX region from 200 individuals by recombination in yeast." Based on...

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