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Tag: "silico" at biology news

Researchers rein in regulatory RNAs

... most studies on SAT pairs have utilized purely in silico approaches; very few have experimentally validated the existence of overlapping RNA molecules in vivo. With this in mind, Dr. Hidenori Kiyosawa, the lead author on the paper, set out to confirm the presence of SATs in a variety of mouse tissue types ...

The synapse is a shotgun

...iological measurements from real neurons. Their in silico modeling indicates that the synapse may behave more like a shotgun than a rifle when it comes to firing the neurotransmitters involved in neuronal communication. The textbook view of the synapse describes it as a place where rifle-like volleys of ne...

Picking particles faster than one at a time

... the highest quality particles, crystallization in silico may need far fewer than hundreds of thousands of particles. "Jacqueline Milne of the National Cancer Institute has demonstrated that high-quality structural maps can be achieved with a few hundred particles or less -- better than those using tens o...

When the going gets tough, slime molds start synthesizing

...puter programs to find, assemble, and translate in silico the relevant raw DNA sequencing fragments first into genes then into the proteins these genes encode, Austin reconstructed two type III PKS-like gene sequences, and also found a surprise. Unexpectedly, these deduced genetic blueprints for type III ...

NYU algorithm enhances ability to detect cancer genes

...algorithm, the authors produced a high fidelity in silico model of cancer, and checked how well they can det...rial manner. Encouraged by the success of their in silico study, they applied the algorithm to currently available patient data, and discovered that they were...

Application of Genomatix in silico methods reveals novel cancer associated genes

Genomatix Software GmbH, an in silico systems biology company with headquarter in Munich...on by siRNA knock-down and RT-PCR confirmed the in silico results. "I am delighted that an ever increasing number of scientists proof the validity of our con...

Executable biology -- Computer science sheds light on animal development

...ermine the fates of individual cells. The novel in silico model is described in a paper appearing May 18, 20...ypotheses that would fill in the missing pieces in silico before performing actual lab experiments. By running their model with a wide variety of gene muta...

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