Nicotine rush hinges on sugar in neurons
...und a water molecule deep in the receptor’s core – significant because proteins normally are filled with hydrophobic (water repellent) matter that helps the structure hold its shape, Chen said. The water molecule may enable the receptor to alter its shape in counterbalance to the bending hinge, said Chen, who ......cientist at the Ann Arbor VA Medical Center. No significant difference occurred in female mice. The scientists can’t explain why at this point. “We don’t know how NDGA is having its effect on survival in this first analysis,” Miller says. “It may be that the female mice because of their hormonal status ha...Enzyme delivered in smaller package protects cells from radiation damage
...an the non-tranfected cells. However, there was no significant difference in survival between MnSOD-minicircle and MnSOD full plasmid transfected cells. According to Dr. Greenberger, whose group is currently conducting a phase I/II clinical trial in lung cancer patients consisting of twice-weekly swallowed MnSOD...Soils offer new hope as carbon sink
...har will last up to hundreds of years. "This is significant for farmer costs because one application of agrichar may be the equivalent of compost applications of the same weight every year for decades. "For the environment, it means soil carbon emissions can be reduced because rapidly decomposing carbon fo...Gene therapy delivery of nerve growth factors reverses erectile dysfunction in animal model
...he treatment, rats administered HSV-GDNF exhibited significant recovery of intracavernous pressure (ICP) and syst...ED. Rats treated with HSV-neurturin also exhibited significant recovery of ICP and AP compared with the control or untreated mice at four weeks after treatment. Fl...Researchers track how spores break out of dormant state
..., partly because of their tough spore coat, have a significant resistance to extreme environmental factors includ...er the vegetative mode of replication. Although significant progress has been made in understanding the biochemical and genetic bases of the spore germination p...Research team identifies new Alzheimer's gene
...ease, even before it strikes” To date, the most significant gene found to predispose an individual to late onset Alzheimer’s (LOAD) has been APOE4. In this latest study, researchers from seven organizations contributed to the genome-wide scan using Affymetrix microarray technology. The team screened the DNA f...Envisat captures first image of Sargassum from space
... show that in this area and season it represents a significant fraction of marine primary productivity." Marine primary production is the process by which floating vegetation, such as phytoplankton and seaweed, absorb atmospheric carbon dioxide through photosynthesis and convert it into organic carbon. By ab...Dirty snow may warm Arctic as much as greenhouse gases
...l of Geophysical Research. Dirty snow has had a significant impact on climate warming since the Industrial Rev...unt of snow impurities in the Arctic have caused a significant temperature response there.” Previous studies have analyzed dirty snow’s effect on climate, but t...Pesticides choke pathway for nature to produce nitrogen for crops
... to two published studies from 2000 that had found significant declines in both crop yield per unit of synthetic nitrogen fertilizer added and also a significant decline in overall symbiotic nitrogen fixation. The most common explanation for the observations ...Millions of children denied drug that costs less than $3 a year
...ladesh also published in this week’s BMJ, found no significant difference in behavioural problems between phenobarbital and another drug called carbamazepine. Despite some limitations, the study provides more evidence to support the use of phenobarbital in developing countries. The burden of untreated epileps...New study finds genetically engineered crops could play a role in sustainable agriculture
...nding genetically modified crops. The results are significant for how we think about technology and the future of sustainable agriculture,” said Peter Kareiva, chief scientist of The Nature Conservancy. According to lead author, Michele Marvier, of Santa Clara University, “We can now answer the question: Do...Salty oceans provide early warning for climate change
...cean circulation speeds up or slows down it causes significant climate change, altering the hydrological cycle and affecting atmospheric circulation patterns too. Currently there is no large-scale salt monitoring system in place in the southern hemisphere oceans. Zahn thinks that regular measurements taken i...Rising skin cancer rates are more likely to affect wealthy people, says 12-year review
Skin cancer levels have shown a significant increase in Northern Ireland since the early 1990s and are more likely to affect men, older people and those living in more affluent areas, according to a study just published in the June issue of British Journal of Dermatology. Researchers who look...Migration alert -- How tumor cells home in on the lymphatic system
... of tumor metastasis. This new understanding holds significant potential for developing anti-metastasis therapies. Scientists know that tumor cells spread via the lymphatic system, but they don’t understand the details of how this deadly migration takes place. In the June 2007 issue of the journal Cancer Cell,...Undergraduate research shows leaderless honeybee organizing
...wn. Pierce’s discovery has to do with detecting a significant new detail concerning the behavior of the European honeybee – perhaps the most studied and economically important insect on Earth. Beyond agriculture, the finding may also have key implications for understanding the dynamics of all social animals, in...Massive herds of animals found to still exist in Southern Sudan
...ys and tracking will reveal that the team missed a significant portion of kob due to the animals’ movements during the surveys. As a result, they believe that there could actually be well over a million white-eared kob in Southern Sudan. Combined with the tiang and Mongalla gazelle, the team believes this would ...Australian wins prestigious prize in biodiversity informatics
...aid "I am honoured by the award. GBIF is making a significant contribution to biodiversity informatics." Paul Flemons applies computer-based ecological modeling to help identify places where lots of species occur together, or species that occur only in very restricted geographical areas. This helps biodiver...... the three groups are directly attributable to the significant effect of level of enculturation. They add that “enculturated chimpanzees may be better at learning within a highly social, interactive context because they have heightened attention to the actions of others.” ...... functional elements have evolved. This could have significant implications for efforts to identify the DNA seque...n to mammalian evolution. In particular, we gained significant insight into DNA sequences that do not encode proteins, which we knew very little about before,” sai...