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Tag: "signature" at biology news

Genome-wide mouse study yields link to human leukemia

... a new tumor suppressor gene and a unique chemical signature implicated in the development of human leukemia, findings that open up a "treasure box" of opportunity and possibility, study authors say. Researchers in The Ohio State University Comprehensive Cancer Center bred a type of mouse that develops acute ...

Study shows nanoshells ideal as chemical nanosensors

...lls are extremely effective atmagnifying the Raman signature of molecules, we found each individualnanoshell acts as an independent Raman enhancer," said lead researcherNaomi Halas, the Stanley C. Moore Professor of Electrical and ComputerEngineering, Professor of Chemistry and Director of Rice's Laboratoryof ...

Brain Scans Reveal How Gene May Boost Schizophrenia Risk

... to a slightly higher risk for schizophrenia and a signature pattern of midbrain dopamine activity.** To see how the two gene versions affect the living human brain, the NIMH researchers scanned 24 healthy young adults twice using PET (positron emission tomography), which uses radioactive tracers to visualize...

Scientists journey to southern Africa to unravel the secret world of elephant communication

...t the footfall of a large animal produces a unique signature that's visible on a spectrogram, making it easy to tell if an elephant, rhino or giraffe has walked by. "We think we can tell the difference between elephants and other species based on the spectral content of their footstep as they pass by a geopho...

Compounds in plastic packaging act as environmental estrogens altering breast genes

...ferentially expressed genes that provide a genomic signature according to the increasing maturation of the orga...In contrast, the BBP exposure modified the genomic signature of the mammary gland primarily at 21 days of age and had less effect later," Moral said. Future stu...

Secret of smallpox's success may lead to bioterror cure

...can no longer hide itself ?it can't camouflage its signature anymore from the cells in its body." Once the virus calls attention to itself, the immune system begins a complex immune response, including developing antigens that specifically target the virus. Because the virus's double-stranded RNA signal is ve...

Amazon source of 5-year-old river breath

...carbon leaving rivers has an identifiable isotopic signature of pasture grasses. "You're changing the land use, changing vegetation and other conditions. In terms of what's being respired, the system is responding fairly quickly," Mayorga says. "Human and natural systems, in turn, will be impacted." No previ...

Carnegie Mellon University research reveals how cells process large genes

...from ratchetting point to ratchetting point, small signature loops of RNA called lariats are released from the intron. Repeated over and over, recursive splicing eventually binds, or ligates, two distant exons. Lopez's team developed molecular tools to analyze the lariats released from any intron during spli...

Reversal of role for a viral protein associated with the development of lymphoma

...from ratchetting point to ratchetting point, small signature loops of RNA called lariats are released from the intron. Repeated over and over, recursive splicing eventually binds, or ligates, two distant exons. Lopez's team developed molecular tools to analyze the lariats released from any intron during spli...

Neurologix announces positive results of gene therapy clinical trial in Parkinson's disease

...lectrode was slowly moved towards the STN. Once a signature firing pattern was obtained confirming that the electrode was in the STN, the fine-wire electrode was removed, leaving only the microelectrode sheath through which a hair-thin (165 micron) hollow tube was inserted. Thirty-five microliters containing...

Rodent social behavior encoded in junk DNA

...," noted Hammock. Each animal species has its own signature microsatellites; for example, the repeating letter sequences are much longer in monogamous than in polygamous vole species. But even within a species, there are differences in the number of letters in the sequence among individuals. The researchers ...

Eleven gene 'signature' reliably predicts cancer prognosis

...a stem cell-like expression profile of the 11-gene signature in primary tumors is a very consistent and powerfu...Microarray analysis identifies a death from cancer signature predicting therapy failure in patients with multiple types of cancer ...

Immune system has evolved to prevent autoimmune disease

... are made by B cells. Each antibody has a chemical signature that allows it to bind only with a particular sequence of amino acids. "In our study, we first sought to understand the evolutionary rules that govern the way the immune system responds to an infection," Deem said. "With that framework in place, we ...

NHGRI expands effort to revolutionize sequencing technologies

...scent polymerase and the nucleotide, which emits a signature detectable in real-time. Xiaohua Huang, Ph.D., University of California, San Diego, La Jolla. $750,000 (3 years) "Massively Parallel Cloning and Sequencing of DNA" The goal of this project is to develop two innovative technologies: massively parall...

Solexa and collaborating scientists illuminate the small RNA component of the transcriptome

...ore than two million short DNA sequences, known as signature sequences or sequence tags, to identify and quanti...be sites of considerable small RNA activity. "The signature sequencing approach makes possible the study of global identity, regulation and function of small RN...

War on terror meets war on cancer

...here the bacteria were grown based on the isotopic signature of the water in which they were cultured. Findings Suggest a New Way to Study Eating Disorders "One area where our results could prove very useful is in assessing metabolic activity," Hegg says. "Being able to accurately measure this number is of...

Gene controls whether fear is a factor

...classes, each of which may have a unique molecular signature requiring distinctive approaches to therapy, the researchers said. ...

Team led by Carnegie Mellon University scientist finds first evidence of a living memory trace

...stimulus. These investigations haven't retrieved a signature of a stimulus, whereas we have." The experiments... exposure to an odor, but you can still detect its signature features minutes afterwards," said Galán. A future question that could be addressed using this res...

Key brain regulatory gene shows evolution in humans

...reduced variation within them. Such a pattern is a signature of evolutionary selection acting on the genetic sequence, said Wray. Still mysterious, he said, is how the prodynorphin gene changes affect human neural development. "All we can conclude now is that this gene is a very strong candidate for having a...

UCLA discovery will aid in treatment of patients with a deadly brain cancer

... class of drugs than tumors in which the molecular signature is absent. The discovery of the telltale molecular signature ?the expression of a mutant protein and the presence of a tumor suppressor protein called PTEN ?will...

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