New study finds how cells with damaged DNA alert the immune system
...er cells in the fight, triggering a mechanism that signals other cells - specifically NK cells - to attack. It could be another ingenious trick that the body uses to ward off cancerous cells." Interestingly, the NKG2D receptor is also found on the CD8+ T cell, a type of immune cell that acts as a sentry wit...Renewed hope for Parkinson's patients
...er cells in the fight, triggering a mechanism that signals other cells - specifically NK cells - to attack. It could be another ingenious trick that the body uses to ward off cancerous cells." Interestingly, the NKG2D receptor is also found on the CD8+ T cell, a type of immune cell that acts as a sentry wit...Defective Gene Linked to Two Inherited Immune Deficiencies
...tibodies such as IgA and IgG. More important, TACI signals B cells to produce antibodies against specific invading bacteria and viruses. Because TACI mutations are genetically dominant, a person with TACI mutations in one of the two TACI genes he or she inherits is unable to mount a strong antibody response...Purdue researchers find key to rice blast fungus
...ore than 40 GPCRs that probably are regulating the signals at the beginning of the penetration pathway. "We are working on the basic infection process," Xu said. "We want to know what genetic mechanisms regulate this process, how the fungus spores recognize the plant surface, and how they know to penetrate ...What Makes The Brain Tick, Tick, Tick: Researchers Gaining New Insights Into Brain's Internal Clock
...armacological tools, recording of electrical brain signals in ensembles of brain cells and functional magnetic resonance imaging of the brain. For example, they are studying how the clock's ticking changes in Parkinson's patients as they change levels of their medication, which effects the amount of dopamin...Agreement will speed research on microbicides for women
...tibodies such as IgA and IgG. More important, TACI signals B cells to produce antibodies against specific invading bacteria and viruses. Because TACI mutations are genetically dominant, a person with TACI mutations in one of the two TACI genes he or she inherits is unable to mount a strong antibody response...Biologists Crack Genetic Code for Specialized Spider Silk
...tibodies such as IgA and IgG. More important, TACI signals B cells to produce antibodies against specific invading bacteria and viruses. Because TACI mutations are genetically dominant, a person with TACI mutations in one of the two TACI genes he or she inherits is unable to mount a strong antibody response...Grasshopper love songs give insight into sensory tuning
...itory nerves and measured the electrophysiological signals reflecting the reactions of the auditory neurons t...ike the rustling of grass and insect communication signals such as grasshopper or cricket mating calls. They found that the OSEs of the receptors particularly...An essential regulator of body weight revealed
...g out the body's diverse and sometimes conflicting signals about hunger and satiety falls to a small cluster ...pes of neurons that recognize and respond to these signals are found in the arcuate nucleus. The first of these, known as POMC (pro-opiomelanocortin) neurons, ...Bone marrow stem cells may heal hearts even years after heart attacks
...lls that line blood vessels. In addition, chemical signals from the bone marrow stem cells may stimulate the growth of surviving heart muscle tissue, prompt stem cells already within the heart into action, or perhaps fuse with and revitalize damaged heart muscle cells. "It should be noted that until now onl...Scientists closer to new cancer detection method
...many other molecules, you have to sort through the signals from the other molecules," Tan said. "This technique solves the problem caused by background signals from both the probe and the biological fluids where the proteins reside. We have engineered a molecu...Researchers use brain scans to predict behavior
... trial. One speculation was that some of the brain signals they detected might be signs of the brain's strugg...ception not only depends on the quality of sensory signals but also on the variability of internal signals. Sapir A, d'Avossa G, McAvoy M, Shulman GL, Corbet...Study provides insight into cellular defenses against genetic mutation
...ation is the inclusion of premature "stop reading" signals (stop codons) within mRNAs. Called "frameshift" or "nonsense" mutations, they order the genetic process to stop reading part way through the instructions, resulting in the building of incomplete proteins. Affected mRNAs create shortened, disabled pro...UT Southwestern researchers develop screening test for cells that activate immune system
... a fluorescent signal only when sensing activation signals so that you can identify immuno-stimulatory agents very easily," said Dr. Takashima. Immuno-stimulatory agents launch the immune system. The research appears on Blood magazine's online Web site and will appear in a future issue. "We have optimized ...Beach pollution is worst during new and full moon
... are unknown," Boehm says. "Because we found tidal signals in enterococci densities at beaches with no obvious point source, like storm drains and creeks, this suggests that there is a widespread tidally forced source of enterococci at beaches." Boehm suggests several candidates for this "mystery" source, i...Biotechnology's newest chemical tool
...rosthesis because only a limited number of control signals are available for user's voluntary control," says project manager, Dr Lucia Beccai. Importantly, it also means less user effort is required to control the hand during daylong use. The CYBERHAND prototype integrates the two types of human senses. On...New factor implicated in allergy and asthma attacks
...ents in the pollen makes that possible." These two signals play a vital role in inducing allergic inflammation. These findings suggest that antioxidant substances may be useful in forestalling allergy or asthma attacks. Sur and Boldogh predict that this new paradigm of initiation of allergic inflammation wi...Researchers find gland that tells fruit flies when to stop growing
...n organ that assesses the size of the juvenile and signals when it has reached a critical weight to begin met...ng the larval stage. The gland then sends hormonal signals when it senses the fly has reached a size appropriate to enter adulthood. The scientists found they......biosafety' greenhouse ( see $12 million greenhouse signals Kenyan GM commitment ). When the first IRMA maize seeds were sown outside in May, Kenya became the first African country after South Africa to plant GM maize in open fields ( see Kenya begins first open field trials of GM maize ). The IRMA research...... Callaway says, or a positive feedback of chemical signals across neuronal synapses would result in a myriad of disorders, including epilepsy. They simultaneously measured activity in both a specific type of inhibitory neuron, called fast-spiking, and a neighboring excitatory neuron. They then stimulated on...