signal 2 6

Tag: "signal" at biology news

Scientists use gene transfer technology and common virus to block neuropathic pain

...," says Fink. "If we can block transmission of the signal at the first neural synapse, it will never reach the brain and you won't feel pain." That's where the herpes-based vector comes in. Although scientists can use many kinds of vectors to transfer genes into living cells, HSV has a natural ability to t...

Yale scientists identify structure for RNA quality control

...th anti-Ro antibodies often have babies with heart signal conduction defects; some scientists believe that t...th anti-Ro antibodies often have babies with heart signal conduction defects; some scientists believe that the antibodies may cause the defects. "Although Ro ...

NHGRI expands effort to revolutionize sequencing technologies

...forth between electrodes, measuring the electrical signal associated with each specific base. Stephen W. Turner, Ph.D., Nanofluidics, Menlo Park, Calif. $6.6 million (3 years) "Real-Time Multiplex Single-Molecule DNA Sequencing" This group will leverage their "zero-mode waveguide" technology to detect sin...

OHSU researchers discover potential mechanism to repair brain damage linked to Multiple Sclerosis

...r studies have revealed that there is a particular signal in the damaged brain that prevents these cells from restoring lost myelin. We're hopeful that we can develop methods to counteract this process in animal models in our search for human treatments." Other key OHSU researchers involved in the study ar...

Molecular Partners Required For Appropriate Neuronal Gene Repression

...r studies have revealed that there is a particular signal in the damaged brain that prevents these cells from restoring lost myelin. We're hopeful that we can develop methods to counteract this process in animal models in our search for human treatments." Other key OHSU researchers involved in the study ar...

A step toward the $1,000 personal genome using readily available lab equipment

...ts attached to one-micron beads, allowing for high signal density in a small area that is still large enough to be resolved through inexpensive optics. One of four fluorescent dyes corresponding to the four DNA bases binds at a specific location on the genetic sequence, depending on which DNA base is presen...

Newly recognized gene mutation may reduce seeds, resurrect plants

...ation of the cuticle that coats plant surfaces may signal whether a seed develops to maturity or is aborted early due to a defective embryo. "This is interesting because in crop production a number of plants have a problem of reduced yield due to seed or fruit abortion," Jenks said. "It's thought that plan...

Purdue researchers find key to rice blast fungus

...e penetration process, which is the beginning of a signal transduction pathway," said Xu, who also was a member of an international research team that published the rice blast fungus genome in the April 21 issue of Nature. This pathway is the communications highway that passes information and instructions f...

What Makes The Brain Tick, Tick, Tick: Researchers Gaining New Insights Into Brain's Internal Clock

... techniques to try to identify this "baton" timing signal and to refine the theory. These include studies using genetically modified mice, pharmacological tools, recording of electrical brain signals in ensembles of brain cells and functional magnetic resonance imaging of the brain. For example, they are s...

Scientists closer to new cancer detection method

...sue samples to pinpoint biomarkers - proteins that signal that something is amiss. "Even when the cancer bi...he native fluorescence go away. What's left is the signal from the probe, which is engineered to be more long-lived at about 50 nanoseconds." The result is a...

NC State researchers redesign life for Mars and beyond

... reduces superoxide, which in plants is a chemical signal given off when stressful conditions are encountered. This signal essentially puts the plant on alert, but staying on alert too long can be harmful: If not reduced qu...

Study provides insight into cellular defenses against genetic mutation

... of molecules in the RNA chain. If a stop reading signal occurs too far ahead of the final exon in the chain, as marked by an exon-exon junction complex (EJC), the cell concludes that the stop codon has mistakenly fallen in the middle of a set of instructions. Specifically, Medical Center researchers now b...

Cracking the perception code

...imal's attention over time influence how a sensory signal is interpreted. Howard Hughes Medical Institute (HHMI) international research scholar Ranulfo Romo of the Institute of Cellular Physiology at the National Autonomous University of Mexico and his colleagues--Rogelio Luna and Adrián Hernández, also of...

UT Southwestern researchers develop screening test for cells that activate immune system

... basically engineered DCs to express a fluorescent signal only when sensing activation signals so that you can identify immuno-stimulatory agents very easily," said Dr. Takashima. Immuno-stimulatory agents launch the immune system. The research appears on Blood magazine's online Web site and will appear in...

Customized gene chip provides rapid detection of genetic changes in children's cancer

...rescent tags to shine under laser light. This is a signal that a particular gene variation is present in the...od and from the tumor, and we should see a loss of signal in the cancer," said Dr. Fortina. He noted that the researchers can simultaneously evaluate seven ch...

'Smart' nanoprobes light up disease

...learly distinguishing between the 'cancer is here' signal and the background light which arises from nanostructures not specifically bound to their molecular targets." Rice's technology solves this longstanding problem by using emissive nanoparticles called quantum dots that give off light in the near-infr...

Plant wounds trigger bacteria

...erium , in that they can detect specific chemical signal molecules that are released from plants or animals...ng phenols in a plant wound; the phenols, in turn, signal VirA to add a phosphate (PO4) group to a related protein, VirG, converting it into an active form. ...

Sudden change in social status triggers genetic response in male fish, study finds

...der, the egr-1genes in his brain send an immediate signal to the gonadotropin-releasing hormones cells to start growing. As these cells get bigger, they crank out more and more hormones, transforming the male from doormat to dominant within 10 minutes. In fact, laboratory analysis confirmed that there w...

CO2 sensing proves critical for fungal pathogens to adapt to life in air and human hosts

...earch, the authors identify CO2 as a physiological signal that induces the pathogenic filamentous transition in C. albicans; they also demonstrate that an ancient group of enzymes called adenylyl cyclases are the so-called chemosensors mediating both the CO2 -dependent filamentation in C. albicans and the c...

New vaccine platform may fight infections with causes from influenza to bioterrorism

...ts: the molecule used by activated CD4+ T cells to signal production of antibodies, and importantly, the specific fragment of pneumocystis that receptors on these antibodies recognize. The researchers first identified as key CD40L, a molecule expressed on activated CD4+ T cells that in turn signals other ...

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