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Tag: "signal" at biology news

Affymetrix and Stratagene Announce Strategic Software Alliance

... RMA, GC-RMA, MAS5, and also PLIER, a new advanced signal estimator developed by Affymetrix statisticians. Affymetrix customers will also be given the option of upgrading to Stratagene's ArrayAssist software, which provides advanced downstream analysis capabilities such as gene clustering, pattern detection...

Sequencing of marine bacterium will help study of cell communication

...elease autoinducer molecules. The numbers of these signal molecules increase with cell density, until they initiate various reactions, such as light production ?or, in a pathogen, the release of toxin once a certain level of bacteria build up. Stevens studies the regulation system of the cell-to-cell commu...

Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin

...he polymersome respond with a bright near-infrared signal that can then be detected. "The fluorophores func...t gives rise to an intense, localized fluorescence signal that is uniquely suited for visualizing living biological systems." According to Therein, there is ...

Programmable cells: Engineer turns bacteria into living computers

...it red or green fluorescent light in response to a signal emitted from another set of E. coli. In one experi...een when they sensed a higher concentration of the signal chemical and red when they sensed a lower concentration. In a Petri dish, they formed a bull's-eye p...

PET/MRI scans may help unravel mechanisms of prenatal drug damage

...rm of carbon (carbon-11). This radiotracer emits a signal that is picked up by the PET scanner, which takes snapshots of the tracer's location over time to show how much and how quickly the cocaine (and/or the metabolic byproducts that retain the carbon-11) enters and clears the various organs. The radiotra...

Robot-based system developed at Carnegie Mellon detects life in Chile's Atacama desert

...s, so we are able to capture a strong fluorescence signal during daytime exploration," said Shmuel Weinstein, project manager. During the mission, a remote science team located in Pittsburgh instructed the rover's operations. A ground truth team at the site collected samples studied by the rover to bring b...

Researchers identify protein crucial for survival of Lyme-disease bacterium

...it appears that changes in temperature and acidity signal the bacteria that the nutrient is present, triggering the bacteria to replicate in large numbers and migrate to the tick's salivary glands, where they are transmitted into animals or humans during the tick's feeding process. The energy for replicatio...

Multi-purpose protein regulates new protein synthesis and immune cell development

...tein folding in the endoplasmic reticulum can also signal the nucleus to regulate gene rearrangements required for B cell differentiation," Kaufman says. "It's a completely unexpected observation. Learning more about the IRE1 signaling pathway may lead to new ways to suppress B cell development, which could...

Computational Method Speeds Mapping of Cell Signaling Networks

... approaches. In the past, scientists have treated signal networks like a puzzle--studying them one pathway ...l encounters a foreign invader, it relays a danger signal throughout the cell, activating it for a quick response. These signals prompt activated T-cells to m...

Nanoparticles offer new hope for detection and treatment

...so contain an imaging agent, you can get a visible signal that allows you to measure how much medication got to the tumor," Lanza says. "You would know the same day you treated the patient and if the drug was at a therapeutic level." Using nanoparticles, drug doses could be much smaller than doses typicall...

Medical molecules designed to respond to visible light that can penetrate tissue

...ieve that they can use light at that wavelength to signal manmade molecules to release drugs at disease site...enge has been that tissue blocks light so we can't signal molecules deep within the body to deliver drug therapy," says Brewer, associate professor of chemist...

Two are better than one

...conditions, the HER2 receptor amplifies the growth signal received by the cell. Yarden and Prof. Michael Sela, former president of the Weizmann Institute of Science, and currently a professor in the Institute's Immunology Department, teamed up to create a strategy for the customization of antibodies that wo...

Defenseless plants arm themselves with metals

...he pathway doesn't sense salicylic acid - that the signal is blocked," he said. "It's like yelling into the phone louder and louder, but no one can hear it." Salt and his colleagues also show in the current study that salicylic acid induces production of a molecule called glutathione, a potent antioxidant ...

Study reveals new technique for fingerprinting environmental samples

...sed to reveal environments under stress as well as signal progress in remediating contaminated environments. This may well develop environmental ecology into a fully quantitative science." Dubbed Environmental Genomic Tags, or EGTs, these indicators capture a DNA profile of a particular niche and reflect t...

New understanding of DNA repair may pave way to cancer treatments

...r. Ronai said, "we did experiments that showed the signal was lost because a protein kinase, ATM, modified ATF2 enough to interfere with detection of the ATF2 signal. Soon, work performed by Anindita Bhoumik confirmed that ATF2 is regulated by ATM and that this regulation is central to the cell's ability to...

Decoding the logic of olfaction

...ptor detects an odor molecule, it triggers a nerve signal that travels to a way station in the brain called the olfactory bulb. Signals from the olfactory bulb, in turn, travel to the brain's olfactory cortex. Information from the olfactory cortex is then sent to many regions of the brain, ultimately leadin...

Genpathway and Baylor College of Medicine Identify New Genes in Breast Cancer

...ptor detects an odor molecule, it triggers a nerve signal that travels to a way station in the brain called the olfactory bulb. Signals from the olfactory bulb, in turn, travel to the brain's olfactory cortex. Information from the olfactory cortex is then sent to many regions of the brain, ultimately leadin...

Plant Sacrifices Cells to Fight Invaders

...g a gene that normally propagates a "pro-survival" signal in plant tissue. Without that input, an alternate "pro-death" signal moves out of the infected areas and damages the rest of the plant. The group studied the plant-path...

Scientists discover that three overlapping signals in embryo help get the backbone right

...rs," he said, "so inhibition is just as specific a signal in the embryo as is an activating signal." Since they discovered noggin, Harland and his colleagues have shown that in later stages of development, this protein factor is critical in laying down cartilage to make joints, and even plays an important ...

Advancements In Genomics Foster Deep Sea Discoveries

...ls experience higher pressure, and that triggers a signal transduction event that activates the expression of genes that help the cells to adapt to the increased pressure,?said Bartlett. The scientists found other tantalizing discoveries in Photobacterium profundum, including a novel fermentative process, a...

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