Tag: "signal" at biology news

A gene's first 'kiss' sets off that affair known as puberty

... own version of "It takes two to tango," whereby a signal literally gets turned on by a molecule that is pro...had been identified as a molecule that activates a signal receptor of GPR54, the researchers looked to the nonhuman primate, the only animal with a reproducti...

DNA Molecules Used To Assemble Nanoparticles

...ll, either killing it from within or sending out a signal to identify it. But making the particles is notoriously difficult and time-consuming. The nanoparticle system used by Baker's lab is based on dendrimers, star-like synthetic polymers that can carry a vast array of molecules on the ends of their arms...

Researchers discover way to make cells in the eye sensitive to light

...ly, but the retinal ganglion cells, thecells which signal to the brain, remain intact. The researchers believethat by activating the melanopsin, these cells may gain the ability tosense and respond to light.Professor Mark Hankins, from Imperial College London and Charing CrossHospital, and one of the papers...

Novel technology detects human DNA mutations

...ghly sensitive gold nanoparticle, creates a strong signal accurately indicating the presence of a specific target SNP. Proof of principle, reproducibility, and the robust, simple and rapid characteristics of this technology were demonstrated withunamplified DNA samples representing all possible forms of thr...

New binding target for oncogenic viral protein

...ruction by the cell. Fbw7 recognizes a destruction signal on certain proteins that need to be degraded and b...tigen contains a motif that mimics the destruction signal found in these proteins." However, unlike the other substrates recognized by Fbw7, T antigen is not ...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

...ed amount of insulin later in life, no matter what signal they got from glucose," Dr. Patti said. "The impairment was permanent. It couldn't be corrected even when the body caught up to normal weight." Because studies of mice generally are good predictors of human biology, the Joslin study has important im...

Termites feed through good vibrations

...ovide insights into the "cocktail party effect" of signal processing ?how to ignore most noise but have some...o the large blocks. Prof Lai created an artificial signal similar to that made by the termites chewing the large block, which Dr Evans broadcast into small bl...

Timing is everything: First step in protein building revealed

...les would be closeenough together to create a FRET signal at all," says Maag. "We werevery pleased just to be able to monitor it, and then we were surprisedand pleased by what we saw next."They had expected -- or at least hoped -- to see a shift in the colorof light once the RNA was mixed in. Instead, they ...

Researchers Uncover Key Step In Manufacture of Memory Protein

... be secreted. Once the cell receives an electrical signal from another neuron, these vesicles fuse with the cell’s outer membrane, open up, and release mBDNF. During their research, Dr. Loh and her colleagues observed mice genetically incapable of producing CPE. In these mice, proBDNF could not be delivere...

Plants respond similarly to signals from friends, enemies

...ually acquired genes from rhizobia to exploit this signal pathway," Bird says. ### The research was funded by the National Science Foundation and the North Carolina Research Station. "Root-knot Nematodes and Bacterial Nod Factors Elicit Common Signal Transduction Events in Lotus japonicus" Authors: Ravis...

Color-blind method opens new doors in DNA sequencing

...E gives brighter signals and collects more of that signal by eliminating the need for a prism to separate the light into colors." Metzker is also seeking to develop a chip-based imager than could be used in his overall project on sequencing-by-synthesis (SBS), which is funded by the National Human Genome R...

BRCA1 causes ovarian cancer through indirect, biochemical route

...t the granulosa cells normally give off a chemical signal that stops the epithelial cells from growing out of control. When that chemical signal disappears or is muted by a mutation in the BRCA1 gene, the epithelial cells don't get the message, ...

Scientists discover the cellular roots of graying hair

... cancerous in melanoma,we would love to identify a signal that would make a melanoma cell stopgrowing.?Fisher and the report’s lead author, Emi K. Nishimura, MD, PhD, also ofthe melanoma program, are in the Department of Pediatric Oncology atChildren’s Hospital Boston as well as at Dana-Farber. The secondau...

Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery

... cancerous in melanoma,we would love to identify a signal that would make a melanoma cell stopgrowing.?Fisher and the report’s lead author, Emi K. Nishimura, MD, PhD, also ofthe melanoma program, are in the Department of Pediatric Oncology atChildren’s Hospital Boston as well as at Dana-Farber. The secondau...

Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.

... cancerous in melanoma,we would love to identify a signal that would make a melanoma cell stopgrowing.?Fisher and the report’s lead author, Emi K. Nishimura, MD, PhD, also ofthe melanoma program, are in the Department of Pediatric Oncology atChildren’s Hospital Boston as well as at Dana-Farber. The secondau...

New research questions basic tenet of neuron function

..., or space between nerve cells, where the chemical signal is transmitted to other neurons. It is known that synaptic vesicles release their neurotransmitters in two different "modes" ?one when the neuron is stimulated and actively relaying a message, and the other through spontaneous release when the neuro...

Zebrafish may hold key to understanding human nerve cell development

...cting as an inhibitory cue. It's possiblethat this signal could also play a role in the development of stemc...stem. Much more research is needed toidentify this signal but we're optimistic our work has set the stagefor future discoveries," said Piotrowski.The Universi...

Harmful Bacterium Commonly Found in Poultry May Survive Refrigeration and Frozen Storage Combined

...cting as an inhibitory cue. It's possiblethat this signal could also play a role in the development of stemc...stem. Much more research is needed toidentify this signal but we're optimistic our work has set the stagefor future discoveries," said Piotrowski.The Universi...

GenMAPP 2.0 released

...cting as an inhibitory cue. It's possiblethat this signal could also play a role in the development of stemc...stem. Much more research is needed toidentify this signal but we're optimistic our work has set the stagefor future discoveries," said Piotrowski.The Universi...

Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits

...nylation and splicing, protein phosphorylation and signal transduction, DNA synthesis, nuclear-cytoplasmic transport, and protein folding. Such networks enriched for several functions suggested to the researchers that cellular processes may work together in a coordinated fashion. In contrast, the team did ...

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