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Tag: "side" at biology news

Algal protein in worm neurons allows remote control of behavior by light

..., where it gates the flow of certain ions from one side of the membrane to the other. Such so-called channel proteins play central roles in the activities of neurons and muscle cells, and while some channel proteins are sensitive to chemicals or electrical signals, ChR2 and its relatives are controlled di...

Greasing interferon's gears may pave way to greater therapeutic benefits, fewer side effects

...t, but sometimes find it difficult to tolerate the side effects of the high doses required. "We reasoned...of interferon and receive enhanced benefit without side effects," Holtzman says. The group engineered a mutant Stat1 protein in which the identities of tw...

Effective, safe anthrax vaccine can be grown in tobacco plants

...ensive fermentation process that can cause harmful side effects such as inflammation, flu-like symptoms an...t lacks the bacterial toxin that can cause harmful side effects. Researchers then injected the vaccine into mice to immunize them against anthrax and sent ...

Harnessing genomic research

...ls without affecting normal cells, so avoiding the side effects of hair-loss and nausea that often result from existing therapies. The genes and biological pathway under investigation are involved in hereditary breast and ovarian cancers and have also been linked to other types of cancers. Rapid diagnos...

Gene variation affects tamoxifen's benefit for breast cancer

...I's, are often used to treat hot flashes, a common side effect of tamoxifen. In this current study of 256...oup tended to be less severe, suggesting that this side effect could predict the gene variation. Further studies are needed, but researchers hope one day t...

Bats use touch receptors on wings to fly, catch prey, study finds

...ditory system. The bat's sense of touch has been a side interest since the early 1980s. To test his hypothesis, Zook removed the delicate hairs from bats' wings with a hair removal cream. Then he let them fly. The bats appeared to fly normally when following a straight path, but when they'd try to take ...

USC researchers track down the stem cells that create feathers

...rs, with the lower end of the ring on the anterior side of the follicle, where the rachis-the backbone of the feather-arises. In the Nature paper, Chuong postulates that it is this simple tilting that can transform feathers from radially symmetric to bilaterally symmetric morphologies by producing molecul...

Technique offers new view of dynamic biological landscape

...cal researchers clues to the magnitude of possible side effects of drugs under development. The development of combination drug therapies, such as for cancer or viruses, could also benefit from the E-MAP approach. "In such cases, clinicians want to know whether -- if drugs that inhibit each of two prote...

Study shows combination of immune substances to be safe

...radiation therapy. But interferon can have serious side effects that limit its use. Surprisingly, the two drugs used in sequence caused no serious side effects in patients. "Interferon can be quite toxic when used alone," says principal investigator ...

Eisai announces Phase II data on E7389, a potential new therapy for the treatment of breast cancer

...ary results of this study, the predominant serious side effect related to E7389 was neutropenia (low white blood cell counts). Other side effects were considered mild to moderate and included nausea, fatigue, dehydration, arthralgias, dys...

Mouse study: New muscle-building agent beats all previous ones

...wasting due to diseases like muscular dystrophy or side effects from cancer treatment or AIDS. "This new inhibitor of myostatin, known as ACVR2B, is very potent and gives very dramatic effects in the mice," says Se-Jin Lee, M.D., Ph.D., a professor of molecular biology and genetics in Johns Hopkins' Ins...

Texas scientists discover how a hepatitis C protein promotes liver cancer

... about half the time and often causes debilitating side effects. Those who fail treatment are at risk for fatal cirrhosis or developing liver cancer. Researchers have known for a long time that hepatitis C virus infection can lead to liver cancer. But how the virus goes about this has been unclear. The...

Why the Amazon rainforest is so rich in species

...t butterfly species groups [genera] on the eastern side of the Andes in Eastern Peru. By using a "DNA clock" the scientists were able to calculate the age of the species within each group of species. If the DNA is similar between any pair of species, they must have split recently. If the DNA has diverged ...

Human trial proves ricin vaccine safe, induces neutralizing antibodies; further tests planned

...icipants in the study, however, reported only mild side effects that were consistent with any intramuscular vaccine injection, such as a sore arm or mild headache that might be experienced with a tetanus or a flu shot, said Dr. Robert Munford, a professor of internal medicine and a collaborator on the stu...

Cellular scale drug delivery from the inside out

...drugs to specific cancer cells without the risk of side affects to healthy cells may one day be possible t...uld remain capped and therefore not cause unwanted side affects by damaging healthy cells. To achieve external control, Lin is using iron-oxide nanoparticl...

New male contraceptive clears hurdle

...an 140 men were already using RISUG. Concern about side effects and insufficiency of safety data caused a ...xpert panels subsequently concluded that the major side effect -- several weeks of non-painful scrotal swelling in about a third of the subjects --was not e...

H5N1 avian flu virus vaccine induces immune responses in healthy adults

...eared to be well tolerated: Almost all reported side effects were mild The second dose of vaccine did not cause more local or systemic symptoms than the first Systemic complaints of fever, malaise, muscle aches, headaches and nausea occurred with the same frequency in all dosage groups as in the pl...

Pain killer fights breast cancer by targeting key enzyme

... for aromatase expression and also have diminished side effects," Brueggemeier said. "We are obviously in ...re actually inside the body and what the potential side effects may be." ...

UC Berkeley researchers create a biologically-inspired artificial compound eye

... microlens arrays ?thousands of tiny lenses packed side by side ?with self-aligned, self-written waveguides, that is, light-conducting channels that themselves have...

Low-cost drug gaining favor for use in HIV-infected children in poor countries

... HIV illness, Grimwade said. Every medication has side effects, and the trial did uncover some adverse re...ure and ability to monitor and respond to possible side effects. The WHO updated recommendations -- scheduled to be released early this year -- will provid...

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