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Tag: "side" at biology news

Columbia scientists develop cancer terminator viruses

...Results found that treating the tumors on just one side of the animal with very few injections of this mod...d in the destruction of the tumors on the opposite side of the animal. Instead of carrying IFN-�� as the other virus did, this virus carried a gene called ...

Opiate cocktail may spare cells from morphine's dark side

...opioid methadone, which is tolerated, with limited side effects, at low doses. The authors indeed found that the combination of morphine with the methadone mixture prevented the activation of cellular signaling pathways associated with morphine tolerance and dependence. They also showed, perhaps most imp...

Results of world's first gene therapy trial for arthritis show approach safe, feasible

...fety a key concern, the authors report no clinical side effects up to five years after the procedure and no evidence that the vector, a replication-defective retrovirus called Maloney Murine Leukemia Virus, has since become capable of replication in their patients. "At the outset, our primary objective w...

Computers close in on protein structure prediction

...he computer adds a fuzzy picture of the protruding side chains that give each amino acid its unique identity. The sequence of side chains ultimately gives each protein its characteristic shape by the environment and neighbors they ...

Scientists use gene transfer technology and common virus to block neuropathic pain in animals

...ty record of the HSV vector, which has produced no side effects or complications in many animal studies. “I am a clinical neurologist and I see patients with neuropathic pain,?Fink says. “These patients suffer tremendously and the treatments available to us now have limited effectiveness. Using our herpe...

LIAI scientists make major finding on potential smallpox treatment

...3 antibody stockpiled around the world right along side the supplies of smallpox vaccine. "While we do have a smallpox vaccine, there are concerns because people who are immuno-compromised cannot use the current vaccine," he added, "including infants and the aged." Additionally, if there were a smallpo...

Scientists use gene transfer technology and common virus to block neuropathic pain

...ty record of the HSV vector, which has produced no side effects or complications in many animal studies. "I am a clinical neurologist and I see patients with neuropathic pain," Fink says. "These patients suffer tremendously and the treatments available to us now have limited effectiveness. Using our herp...

Scientists discover genetic pathway responsible for breast cancer cell growth

...often untargeted, which is why patients experience side effects," notes Dr. Giguère. "The more focused the drugs the less side effects and the more chance you have to cure the disease." "Research targeting individual molecules...

Experimental shingles vaccine proves effective in nationwide study

...ain, itching or tingling in an area of skin on one side of the body or face. Then a painful blistering ras...eeze. Simply dressing and having a shirt touch the side of the body that is affected can be excruciating. Postherpetic neuralgia is difficult to treat. Ant...

North & South American researchers find architectural abnormalities in T. cruzi ribosome

...earchers found a gigantic addition tacked onto one side of the small subunit, resembling a turret topped by a spire. "It's larger than anything we've seen anywhere, as far as peripheral additions in ribosomes are concerned," Frank said. "It's almost freestanding." The exact purpose of the turret and its ...

Old drug shows new promise for Huntington's Disease

... for internal use in many countries because of its side effects. In Japan in the late 1950s and 60s, the drug was found to cause a neurologic condition called subacute myelo-optico-neuropathy (SMON), with symptoms including visual loss, muscle weakness, and numbness, in several thousand people. However, n...

Researcher at UGA College of Veterinary Medicine identifies new way of combating viral diseases

...ty of viruses. Blocking Rab9 may have significant side effects, but there are people who live without Rab9, Hodge explained. Although they have metabolic problems, they are generally able to control their condition with diet and medication.Temporarily blocking the Rab9 pathway would be unlikely to harm t...

UT Southwestern researchers discover master switch in cell death

...ns that control cell death.?/p> The beneficial side of cell death ?known as apoptosis ?occurs when it ...mbryo or shapes a developing brain. But the darker side of this complex process manifests itself in cancers when cells don’t die when they’re supposed to. ...

Metal-containing compounds show promise as HIV weapon

...he key drugs used to fight HIV/AIDS, but they have side effects, and viruses can develop resistance to them. "This molecule has all the characteristics of a good starting point for a new class of compounds," said Dr. Zbyszek Otwinowski, associate professor of biochemistry at UT Southwestern and an author...

Purdue researchers find key to rice blast fungus

...arently because the fungus and the grain developed side by side over centuries, according to genetic experts. To overcome the fungus' wiles, researchers need to kno...

Female butterflies go for sparkle -- not size -- when choosing to mate

...ro. None of the variations induced on the ventral side appeared to have any affect on the females' mating...ading the researchers to conclude that the ventral side of the wing does not play a role in the decision making. But when the researchers painted the white...

California computer scientists double volume of data in NIH biotech repository

...e copies of the haplotypes of the parents. As a side effect of their research, the computer scientists are now depositing 15 gigabytes of data into dbSNP, and their article in Genome Research aims to encourage the research community to use the data depository as a scientific resource. Researchers can u...

U-M scientists say fused genes trigger the development of prostate cancer

...e copies of the haplotypes of the parents. As a side effect of their research, the computer scientists are now depositing 15 gigabytes of data into dbSNP, and their article in Genome Research aims to encourage the research community to use the data depository as a scientific resource. Researchers can u...

Bone marrow stem cells may heal hearts even years after heart attacks

...n 'own blood injection or transfusion,' and has no side effects. It needs only bone marrow puncture and cell aspiration with subsequent stem cell preparation," he said. Although this study did not look at how stem cells may heal heart attack damage, other studies have shown that the bone marrow cells can...

Amphetamines reverse Parkinson's disease symptoms in mice

...ines, which are drugs of abuse with many dangerous side effects. The findings rather indicate that drugs w...e important considerations in reducing some of the side effects of current therapy. "The locomotor stimulating effect of amphetamine and its derivatives ar...

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