Protein prevents detrimental immune effects of bacterial sepsis
... allow the modeling of new therapeutics with lower side effects." The importance of this work is underscored by the fact that bacterial sepsis ranked among the top ten causes of death in both adults and neonates in 2002 in the United States (Natl Vital Stat Rep 2005, 53:1-89). The patients at greatest ri......n, than patients receiving paclitaxel alone. Other side effects were similar between the two treatment groups. Bevacizumab, a humanized monoclonal antibody** that already has been approved for metastatic colorectal cancer in combination with chemotherapy, is designed to bind to and inhibit vascular endot...The lopsided brain: Attention bias is shared by humans and birds
...ndency to devote more visual attention to the left side of the visual world than the right side, a phenome...ion--spatial hemineglect--in which the entire left side of the visual world seems nonexistent as the brain performs spatial tasks. In a classic example, a p...Tendency to hair loss inherited from the mother
...ore take after their grandfather on their mother's side rather than their father. However, this defect is not simply caused by one gene: "We have indications that other genes are involved which are independent of the parents' sex," Prof. Nöthen stresses. The hereditary defect can therefore sometimes also ...Gene therapy cures inherited liver disease in rats
...called, was manipulated so that it minimized toxic side effects. This disease involved a lack of a gene that is found in the part of the cell where detoxification occurs. It points the way to using gene therapy to cure and/or treat a host of other disease that occur because of the lack of genes in this ar...Brain May Be Less Plastic Than Hoped
...g surgery can regain motor control on the affected side of their body and go on to develop normal language skills. But in adults, the case for brain plasticity has been less clear. A series of studies in the 1980s and 1990s seemed to show that, in adult animals, neurons “filled in?blank spots in the moto...Discovery clarifies role of peptide in biological clock
...e roughly 10,000 neurons in this nucleus on either side of your brain. The timekeeping mechanism in these cells depends on daily cycles in gene activity. Herzog found in his latest study that the percentage of rhythmic cells in the mutant SCN was very low, and he believes these rhythmic neurons are speci...Science study holds implications for gene therapy and stem cell biology
...r hand, scientists offer caution in regards to the side effects associated with genetic engineering of ste...investigated in this study showed no signs of such side effects. "This is a step forward in our research because it helps us understand which genes are inv...Important discovery about second most fatal cancer
...et # More common in females # More common in right side of colon # Little evidence of tumour immunity # Frequent mutation of an oncogene called BRAF (also mutated in cancer of thyroid, ovary, and melanoma) # Frequent DNA methylation (chemical change which inactivates many genes) # Frequent but variable le...Prescription Drug Patches Gaining Ground, Tackling New Therapies
...tion to improve patient compliance and reduce drug side effects, prescription skin patches are rapidly becoming an important healthcare product category. While quietly gaining market share for the treatment of chronic conditions such as angina, hypertension and HRT, the technology is set to make further i...Chimp genome reveals a retroviral invasion
...ical copies of LTR sequences are created on either side of the retroviral element; the divergence of LTR sequences within a species can be used to estimate the age of an initial infection. Eichler and colleagues estimate that gorillas and chimps were infected about 3 -- 4 million years ago, and baboon and...... transmitter and the receiver are both on the same side of the sample. However, only a tiny fraction of t...human hearing) and picks up the pulse on the other side after it has traveled through the imaged object. The transmitted pulses come from an array of very ...Researchers test new therapy for advanced melanoma
... gene to these tumors reliably and without serious side effects, melanoma and other cancers would be open to many new treatment possibilities." Six years of laboratory studies by Dr. Heller and his colleagues preceded the initial human trial begun earlier this year at Moffitt. The collaboration of USF an...Pair of cancer genes found to drive both cell migration and division
...h outward - PI3K makes PIP3 on the membrane on one side of a cell while PTEN breaks it down on the other side. But when both enzymes are missing, levels of PIP3 remain constant throughout the membrane, and the cell can't migrate properly. In experiments with single-celled amoebae, Devreotes and his team ...Newly discovered protein an important tool for sleeping sickness research
...se is melarsopal, an antiquated drug with terrible side effects, including death. In the February issue (Volume 17, Issue 3) of the journal Molecular Cell, scientists in the Marine Biological Laboratory's (MBL's) Josephine Bay Paul Center for Comparative Molecular Biology and Evolution report their disco...Breakthrough System for Understanding Ocean Plant Life Announced
...se is melarsopal, an antiquated drug with terrible side effects, including death. In the February issue (Volume 17, Issue 3) of the journal Molecular Cell, scientists in the Marine Biological Laboratory's (MBL's) Josephine Bay Paul Center for Comparative Molecular Biology and Evolution report their disco...New book explains antibiotic resistance for a broad audience
...cs work most of the time and work quickly with few side effects. They hate the fact that more and more physicians are refusing to prescribe antibiotics for flu and that patients are being blamed for demanding antibiotics when they shouldn't," says Abigail Salyers of the University of Illinois at Urbana-Ch...Lipids get new comprehensive classification system
...odology is that head groups are drawn on the right side and the hydrocarbon chain extends to the left. In the simplest case of the fatty acid derivatives, the acid group is drawn on the right and the hydrophobic hydrocarbon chain is on the left. Another part of the classification system is a 12 digit ide...Computational Tool Predicts How Drugs Work In Cells, Advancing Efforts To Design Better Medicines
..., eliciting therapeutic responses free of unwanted side effects. The research, which appears in the March 4 issue of Nature Biotechnology, reports on collaborative work by a team of biomedical engineers and chemists at Boston University. The team was led by Tim Gardner, an assistant professor in the Coll......non by which the oceans react to changes on either side of the planet. A research team from the Universitat Autònoma de Barcelona and the Cardiff University has shown for the first time that ocean circulation in the southern hemisphere has, in the past, adapted to sudden changes in the north. The research...