Identical twins may have more differences than meet the eye
...tory. "Nearly every tumor, every human malignancy shows changes in DNA methylation that mess up gene expression," he said. "If we understand what regulates methylation patterns, then we may be able to develop better treatment options for cancer." The researchers received financial support for this work f...Vibrio bacteria could be a risk to fish as well as humans
...killed fish in laboratory conditions. Our research shows that marine vibrios could cause disease to fish and crustaceans. In some cases, only 100 bacterial cells from the pathogens were capable of causing disease. This means that the bacteria are extremely aggressive and could pose a great risk to sea anim...Computer modeling reveals hidden conversations within cells
...effects on cells," explained Hoffmann. "Our model shows that, analogous to how a telephone transmits an infinite number of different signals along a single wire, it is the timing of the proteins' activity that allows them to exert intricate control over the behavior of a cell. The computer model reveals ...Scientists find evidence of catastrophic sand avalanches, sea level changes in Gulf of Mexico
...tory. "Nearly every tumor, every human malignancy shows changes in DNA methylation that mess up gene expression," he said. "If we understand what regulates methylation patterns, then we may be able to develop better treatment options for cancer." The researchers received financial support for this work f...Scientists use gene transfer technology and common virus to block neuropathic pain in animals
...ery to the nervous system is a novel approach that shows tremendous promise for the treatment of neuropathic pain.?/p> In future research, the scientists plan to conduct the first phase I safety trial of a related HSV vector in patients with pain caused by terminal cancer, which has spread to bone. Th...Long-sought flower-inducing molecule found
...her with other data published at the same time, it shows convincingly that the "messenger molecule" produced by FT either is florigen, or an important component of florigen. The researchers have used the small plant model species Arabidopsis in their research. But the group of Ove Nilsson has also other d...New law for resolution allows unprecedented sharpness in fluorescence microscopy
...fourth study [4], the research team from Göttingen shows that using STED, measurement volumes notably below the resolution limit can be produced without confining the solution itself mechanically. This method may substantially improve the analysis of pharmaceutical active ingredients and protein interactio...Virus uses tiny RNA to evade the immune system
...o be a defense by cells against viruses. Our study shows that a virus can also adapt it to evade the immune response," said HHMI investigator Don Ganem, who is at University of California, San Francisco. Ganem studies how viruses infect people and cause disease. When scientists found that RNA interference...Einstein researchers identify new way that bacteria develop resistance to antibiotics
... developed fluoroquinolone resistance. "Our study shows that this novel bacterial mechanism is responsible for the rapid spread of fluoroquinolone resistance that is making hospital-acquired infections so difficult to treat," says Dr. Blanchard. Additional members of the research team were postdoctoral f...Learning how SARS spikes its quarry
...he first stages of infection. The structure, which shows how the spike protein grasps its receptor, may hel...arrison. In particular, he said, the new structure shows how mutation at one of the two sites can enable the animal SARS virus to infect humans, but by itsel...Infectious disease expert warns of spread of Rocky Mountain spotted fever
...oved with their owners into the area. "This study shows that Rocky Mountain spotted fever can show up in unexpected places, and the study should put physicians on alert for the earliest signs and symptoms of the disease," says Dumler. "Our next step is to develop faster and more reliable tests to detect t...Promising therapies for haemophilia & heart disease
...of the arteries) and the work of our collaborators shows that the events leading to deep vein thrombosis are reduced. P-selectin inhibitors have also been shown to be anti-thrombotic in early human trials" Measurement of P-selectin levels in the blood stream may provide a new diagnostic tool to identify p...Exercise aside, genes may ultimately dictate seniors' mobility
... genetic interaction in functioning and aging, and shows people are already pre-selected, that there are genes that interact with behavior to affect mobility," Pahor said. Decreasing mobility, along with lack of muscle strength and a decline in aerobic ability, are common aspects of aging that can lead to......eart and skeletal muscle. Strikingly, their study shows that, in Drosophila embryos, mir-1 expression is not required for mesodermal cell fate decisions or cell proliferation during embryogenesis, but rather, that it appears to act to reinforce and maintain cell identity during times of rapid growth. Th...Genetic variation alters response to common anti-clotting drug
...es," said NIH Director Elias A. Zerhouni, M.D. "It shows one important way in which we are beginning to apply knowledge about the human genome for treating disease and improving human health." Warfarin (trade names include CoumadinTM) is the most commonly prescribed oral anti-clotting drug. Allan E. Retti...New discovery blurs distinction between human cells and those of bacteria
...nt Morgan Beeby. The structure of the carboxysome shows a repeating pattern of six protein molecules packed closely together. "We didn't know six would be the magic number," Yeates said. "What surprises me is how nearly these six protein molecules fill the space between them. If you take six pennies and ...Nighttime Dying Linked To Sleep Apnea From Brain Cell Loss
...nt Morgan Beeby. The structure of the carboxysome shows a repeating pattern of six protein molecules packed closely together. "We didn't know six would be the magic number," Yeates said. "What surprises me is how nearly these six protein molecules fill the space between them. If you take six pennies and ...NASA satellite data provides rapid analysis of Amazon deforestation
...is technology continues to advance and a new study shows that NASA satellite images can allow scientists to...the most exciting finding of this study is that it shows MODIS can permit regional analyses of land cover in a matter of days, a substantial reduction in eff...Field tested: Grasslands won't help buffer climate change as carbon dioxide levels rise
...nt Morgan Beeby. The structure of the carboxysome shows a repeating pattern of six protein molecules packed closely together. "We didn't know six would be the magic number," Yeates said. "What surprises me is how nearly these six protein molecules fill the space between them. If you take six pennies and ...Tropical Deforestation affects rainfall in the U.S. and around the globe
...lutants receive considerable attention, this study shows that land-cover change is another important parameter that needs to be considered in climate policies, especially since deforestation rates in tropical Africa, Southeast Asia, and South America have remained constant or have increased over the past t...