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Tag: "shown" at biology news

Exploring the molecular origin of blood clot flexibility

... Medicine and the School of Arts and Sciences have shown that a well-known protein structure acts as a molecular spring, explaining one way that clots may stretch and bend under such physical stresses as blood flow. They report their findings in a Letter in the latest online edition of the Biophysical Jour...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

...o the epidermal growth factor, has been previously shown to be effective in treating metastatic colorectal cancer. Dr. Laurent-Puig and his colleagues studied 114 patients who had been given cetuximab in combination with another drug, irinotecan. According to the researchers, approximately 30 perc...

Prenatal cocaine's lasting cellular effects

...the City University of New York, we had previously shown a decrease in signaling of a particular receptor protein, the dopamine D1 receptor," Stanwood said. "We know that this receptor is involved in regulating the formation of cortical circuitry. It's also involved in the behavioral effects of amphetamine...

Warming oceans threaten Antarctic glaciers

...ur major glaciers in East and West Antarctica were shown to be retreating in unison, raising concerns that global sea level could rapidly rise if the oceans continue to warm. Dr. Andrew Shepherd, at the University of Edinburgh’s School of GeoSciences, said: "Our assessment confirms that just one type of...

Biologists prove critical step in membrane fusion

...sicles are rapidly released. Previous research has shown that special proteins kept these vesicles tethered to the egg’s membrane. What about the membranes? What do they look like before vesicle cargo is released? Wessel and his collaborators discovered that the membranes of the egg and the vesicles are...

Cancer tip -- Nanoparticles can damage DNA, increase cancer risk

...e important," Pacheco said. "Several studies have shown that smaller particles are more likely to enter cells and cause more toxicity." According to Pacheco, what makes matters worse is the fact that so far, aside from preventing their release, there are no known ways to prevent the harmful effects of...

Selective marker found to indicate aggressive form of breast cancer

...cult to manage, but several important studies have shown that it is more likely than other breast cancer subtypes to respond to certain types of therapy, which highlights the need for a definitive diagnostic marker." The basal epithelial breast cancer subtype represents 17 to 37 percent of all breast ca...

Racing neurons control whether we stop or go

... that the results predicted by the model and those shown by the neural activity matched. "For most of the race, ‘stop?and ‘go?act independently. ‘Stop?interacts with ‘go?very briefly—it basically has one chance to knock ‘go?out of the race. It needs to react strongly and rapidly after the stop signal i...

OHSU lab finds meth receptor that could lead to therapy

...overed signaling system in the brain has just been shown to be turned on by methamphetamine, an Oregon Health & Science University study found. The signaling system could soon become a target for therapies aiming to reverse meth’s adverse health effects as well as reduce the craving that drives its ab...

Researchers find hepatitis A and hepatitis C attack same protein to block immune defenses

...nhibitor of virus replication. Recent research has shown that hepatitis C generates a protein called NS3/4A that chops up MAVS, interfering with immune signaling and possibly providing the cover the virus needs to survive so long in the liver. Now, Lemon and his group have demonstrated that hepatitis A doe...

New research shows that flu is a trigger of heart attacks

...he lead author of the report. "Our research has shown that influenza epidemics are associated with a ris...tween 1993 and 2000 in St Petersburg that had been shown by autopsy reports to be due to coronary heart disease. "This was a population where only a small...

Xylitol reduces risk of cavities

...of lactic acid in plaque. In another study it was shown that a single higher intake of xylitol for a limited time reduced the degree of acidity in plaque between teeth. In a field study involving 128 children aged 7?2, the subjects were asked to chew gum three times a day, with a total daily dose of 6....

How genetic malfunction causes a form of retardation

...te one cell type versus another. Moreover, we have shown that the same constitutively activated SHP-2 that occurs in a subpopulation of NS patients causes aberrant neural development in mice, providing a potential explanation for the cognitive dysfunction and neuroanatomical perturbations observed in this ...

Producing medicines in plant seeds

...tive battery of tests. These laboratory tests have shown that the antibody variants produced in plants are just as effective as whole human antibodies in protecting animal cells against infection with the Hepatitis A virus. This is a significant step forward in making protein production in plants a real...

Inflammation may play role in metastasis of prostate cancer

... progression of metastasis," said Karin. "We have shown that proteins produced by inflammatory cells are t...clear factor Kappa-B (RANK). RANK ligand has been shown in previous studies to be an important inflammatory protein (cytokine) that can lead to bone loss th...

Stem cells decrease ischemic injury and restore brain function

...d be substituted by stem cells. A few studies have shown that these cells can be effective, although various issues about their use and the mechanisms of their protective action remained unsolved," says Maria Grazia De Simoni. "Our research has underlined a possible mechanism of action. Once introduced...

Intravenous nanoparticle gene therapy shows activity in stage IV lung cancer

...n into tumors. "This is the first time anyone has shown that a gene can be injected and then be taken up ...cian, I am very cautious about saying that we have shown clinical activity at this point. We have some encouraging data. The number of patients is too smal...

Researchers hot on the trail of brain cell degeneration

...th a variety of different mechanisms. Research has shown that the destruction of cells be over-stimulation depends on excess entry of calcium into the cells. Researchers have long been trying to map how cells generate destruction signals in response to the calcium, in the hope of finding new targets for dr...

Researchers uncover protection mechanism of radiation-resistant bacterium

...pothesis. However, D. radiodurans has subsequently shown nothing obviously unusual in its DNA repair components, and it appears that bacteria at differing levels of resistance sustain the same amount of DNA damage from a given dose of IR. Additionally, many bacteria are killed by IR doses that actually cau...

Scientists unlock secret of what makes plants flower

...nse to changes in day length. Earlier research had shown that plants' leaves perceived seasonal changes in day length, which triggers a long-distance signal to travel through the plant's vascular system from the leaf to the shoot apex, where flowering is induced. However, the identity of the long-distance...

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