Cancer stem cells similar to normal stem cells can thwart anti-cancer agents
...small subset of cancer stem cells, which they have shown share the same protective mechanisms as normal lung stem cells. They are presenting this ground-breaking research at the Tissue Engineering and Regenerative Medicine International Society (TERMIS) North American Chapter meeting being held June 13 to ...UCF nanoparticle offers promise for treating glaucoma
...e eye, earlier experiments with nanoparticles have shown not only high penetration rates but also little pa...article and bound it with a compound that has been shown to block the activity of an enzyme (hCAII) believed to play a central role in causing glaucoma. T...Blood-brain barrier breached by new therapeutic strategy
...art of the National Institutes of Health, have now shown that a short protein (peptide) from the rabies vir...strip, called a small interfering RNA (siRNA), was shown to protect mice from infection caused by the Japanese encephalitis virus (JEV). Manjunath N. Swamy...Endosome-mediated signaling in plants
...rk in animal cells over the past several years has shown that receptor endocytosis can actually facilitate signaling through the cell, by bringing signaling components in contact with their activated receptors. Drs. Geldner, Chory and collaborators now extend the range of endosome-mediated signaling int...Reconstructing the biology of extinct species: A new approach
...tion during the week of 18 to 22 June. "We have shown that there is a fundamental adaptive mechanism linking a species' locomotion with the sensory systems that process information about its environment," says Alan Walker, Evan Pugh Professor of Anthropology and Biology at Penn State University, one of ...Human genetic 'deserts' are teeming with significant life
...ety in these structures”, he says. “Our work has shown that the human genome is far more complex than anyone could have imagined, even ten years ago. Understanding these complexities is essential to the development of effective and safe genetic medicine in the future.”...Turn-ons and turn-offs for neurons
...enes for example in cognition in the mouse, as was shown in key studies from 1996. But in spite of the published success, others scientists report some difficulties: in some experiments the full reactivation of Tet-regulated genes failed. Mazahir T. Hasan and colleagues at the Max Planck Institute for Medi...Putting feelings into words produces therapeutic effects in the brain
...ieberman noted. Creswell said Lieberman has now shown in a series of studies that simply labeling emotio... for thousands of years.” Previous studies have shown that mindfulness meditation is effective in reducing a variety of chronic pain conditions, skin dise...Understanding why C. difficile causes disease -- it's hungry
...nited States and Canada. Recently, this strain was shown to be responsible for more than half of all cases in a representative sampling in Quebec. The highly virulent strain has a much higher toxin production which leads to more destructive and deadly disease, says Vivian Loo of McGill University. So...Adult stem cells from human cord umbilical cord blood successfully engineered to make insulin
...also found that, just as embryonic cells have been shown to do, these adult stem cells produced both C-peptide, a part of the insulin precursor protein, and insulin itself. Confirming the presence of the C-peptide was especially crucial, the researchers suggested, because although insulin is often found in...'Smart' mice teach scientists about learning process, brain disorders
...y advanced thing to do," Dr. Bibb said. "It’s been shown that it can be done, but we put the system together and actually applied it." Normally, Cdk5 works with another enzyme to break up a molecule called NR2B, which is found in nerve-cell membranes and stimulates the cell to fire when a nerve-cell-sig...Treating HIV in war zones -- Public health emergencies need rapid advice from WHO
...s in non-conflict settings. "Our experience has shown us that one of the keys to successful provision of ART in conflict settings is preparation for disruption," say the authors. Some of the crucial contingency measures include: Providing patients with extra emergency drug supplies that can be t...Avian influenza survivors' antibodies effective at neutralising H5N1 strain
...access journal PLoS Medicine, the researchers have shown how specific antibodies taken from avian flu survi...ergy and Infectious Diseases in Bethesda, US, have shown that monoclonal antibodies generated from blood of human survivors of the H5N1 virus are effective a...Focused ultrasound relieves fibroid symptoms in women
...serious adverse effects were reported. "We have shown that treating fibroids with an optimized, less restrictive protocol allows for treatment of a greater fibroid volume, which results in even greater symptomatic relief at clinical follow-up," Dr. Fennessy said....Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism
...ently inflammation and infectious agents have been shown to play an important role in the onset of acute ca...nova, Italy. The same researchers have already shown that Cytomegalovirus infection can be responsible of the initial vascular lesions typical of the ath...Human stem cell treatment restores motor function in paralyzed rats
...of spastic movements and improved muscle tone, was shown in 40 to 50 percent of the animals tested. A post-mortem study of those animals showed a robust maturation of neurons and an increase in the expression of inhibitory neurotransmitters in the spinal cords of rats that received transplanted neuronal c...Pistachios lower cholesterol, provide antioxidants
... by reducing serum oxidized LDL. "Our study has shown that pistachios, eaten with a heart healthy diet, may decrease a person's CVD risk profile," says Dr. Penny Kris-Etherton, distinguished professor of nutrition and primary investigator of the study....Mice with a migraine show signs of brain damage
...unctionally impaired from the pain. It’s also been shown recently that with repeated migraines, a person’s cognitive abilities decrease. But actually doing damage to the brain ?that is a surprise.? Deborah Friedman, M.D., a neurologist who was not involved in the study, says that a few studies have found...Salk scientists hammer out a pathway that promotes muscle cell survival in mice
...anisms of gene regulation, CREB and HDAC, and have shown that this pathway plays a major role in maintaining normal muscle function," said Berdeaux. "Now it remains to be seen how this pathway works in muscle under different conditions, such as during exercise, as well as what part it plays in maintaining ......th up to four years of follow-up data, Stratta has shown that success rates with these organs are equivalent to those of conventional donors, in part because of appropriate donor and recipient matching through using the pump to assess viability and function. ...