Morning grogginess more debilitating than sleep deprivation, according to CU-Boulder study
...ning than after extended sleep deprivation. For a short period, at least, the effects of sleep inertia may be as bad as or worse than being legally drunk." Following six nights of monitored sleep lasting eight hours per night, the study participants were given a performance test that involved adding rand...Plant-derived vaccines safeguard against deadly plague
...duces really high levels of antigens in relatively short periods of time." The researchers modified tobacco plants to make high levels of the plague antigens F1, V and a combination of the two, a so-called F1-V fusion antigen. All are known to be important for the plague bacteria to produce its toxic effe...... of strawberry. However, these efforts have fallen short of the requirements to support large-scale studies...al detail." Due to the small size of its genome, short reproductive cycle and small plant size, F. vesca is an ideal model system for genomics in commercia...New test to detect rare proteins in blood
...tecting molecules by the new method, called FACTT, short for Florescent Amplification Catalyzed by T7-polymerase Technique, is five orders of magnitude (100,000 times) greater than that of ELISA, the Penn researchers found. Senior author Mark I. Greene MD, PhD, the John Eckman Professor of Medical Scien...Viral 'fitness' explains different resistance patterns to aids drugs
...ss they are taking most of their PIs but fall just short of full viral suppression." The researchers found that NNRTI-resistant virus has an advantage over sensitive virus even at very low levels of adherence. This happens because only a single mutation is required to create high-level NNRTI resistance a...UMaine teams with fishermen to study affects of trawling on seafloor ecology
... found that significant gains had been made in the short term. "Scientists were predicting it would take decades for recovery, but didn't have an opportunity to look at it," said Knight. "This is the first project that has been able to look at areas closed for six years. We're already seeing signs of reco......ntext: this is dicaffeoyl quinic acid, or DCQA for short ?the highly prized prototype for a new group of AIDS drugs. One million euros per gram 'Dicaffeoyl quinic acid can prevent the HI virus from reproducing, at least in cell cultures,' explains Claudio Cerboncini, who is now working at the caesar ......s study, five household dogs were trained within a short 3-week period to detect lung or breast cancer by sniffing the breath of cancer participants. The trial itself was comprised of 86 cancer patients (55 with lung cancer and 31 with breast cancer) and a control sample of 83 healthy patients. All cancer ...Resveratrol prolongs lifespan and delays onset of aging-related traits in a short-lived vertebrate
...l organisms because of their very small size, very short natural lifespan, and affordable cultivation costs. Laboratory mice, on the other hand, live more than two years and are relatively expensive to maintain, making large-scale, life-long pharmacological trials in mice unaffordable. Recently, a small f...History of human cannibalism eats away at researchers
... selection, purifying selection, and possibly even short periods of balancing selection." On a more technical note, the study cautions researchers involved in SNP-based population genetics studies. The work is one of the first to empirically demonstrate how SNP ascertainment can introduce a strong bias ...Gene thwarts some pathogens, gives access to others, could save crops
... growth and development as evidenced by abnormally short roots, overabundance of root hairs and wrinkly leaves on plants lacking the gene, according to the scientists. The gene produces a protein located in the plant cell membranes and shows activity that is characteristic of proteins that act as enzymes....Finding a virus is not all bad news
...the animal's own genes has been more effective for short term information and is both cheaper and a far quicker process," says Alexei. The research team's findings were recently published in Science, one of the world's leading science journals for new research. ...Engineered heart tissue offers insights into irregular heartbeats, defibrillator failure
...of ventricular tachycardia," Bursac said. "After a short period, we applied trains of pulses in an attempt to terminate this wave." The pulses successfully halted the wave 80 percent of the time, they reported. In the remaining cases, however, the pulses converted the single wave into multiple waves that...New method enables gene disruption in destructive fungal pathogen
...or easy selection of the new mutants, as well as a short partial target gene that integrates and disrupts genes in the pathogen's genome. Richard Oliver, director of the Australian Centre for Necrotrophic Fungal Pathogens and professor of Molecular Plant Pathology at Murdoch University, Perth, commented:...Salmonella bacteria use RNA to assess and adjust magnesium levels
...ve added a gene in the bacterium Salmonella to the short list of genes regulated by a new mechanism known as the riboswitch. The Salmonella riboswitch is the first to sense and respond to a metal ion, substantially expanding the types of molecules that riboswitches can detect to help cells assess and rea...New method for identifying microbes
... to identify key segments of genetic code that are short enough to be sequenced rapidly and can readily distinguish among species. The Brookhaven team has developed just such a technique, which they call "single point genome signature tagging." Using enzymes that recognize specific sequences in the geneti...Radiotherapy advance points way to noninvasive brain cancer treatment
...rons are very destructive for DNA, but have a very short range of action. Therefore, to induce DNA damage that the cancer cells cannot repair, and consequently cell death, gadolinium atoms must be localized in the nuclei of cancer cells." De Stasio adds that, for the treatment to be effective, gadolinium ...Computer scientist sorts out confusable drug names
...nds," he added. Drug companies covet finding good, short drug names that are easy to remember, Kondrak noted, adding, "the FDA and other drug agencies need to balance this against confusing the names with existing ones--it's a serious problem." Kondrak co-authored a paper on this topic that was recently p...Weighting cancer drugs to make them hit tumors harder
...s more effectively. Chemotherapy drugs often fall short of achieving their full impact because the drugs diffuse in and out of the tumor too rapidly, said the scientists from Duke University Medical Center and Duke's Pratt School of Engineering. The scientists increased the size of the drug by adding a "...Evolutionary scrap-heap challenge: Antifreeze fish make sense out of junk DNA
...t be an exception to this because it consists of a short repetitive sequence that only needs to be duplicated four times to give a fully functioning protein". ...