LIAI scientists make major finding on potential smallpox treatment
...ion, similar to how an antibiotic treats and for a short time protects against a bacterial infection. "This makes Dr. Crotty's research even more interesting because his findings appear to offer a way to successfully treat the virus," Kronenberg said. "This could be very important should people become in...Optimizing cell therapy against tumors is a balancing ACT
... is to keep the in vitro T cell expansion phase as short as possible to keep them naïve. These findings are important for development of improved adoptive immunotherapy approaches for treating tumors and established infectious diseases. TITLE: Acquisition of full effector function in vitro paradoxically i...Eleven gene 'signature' reliably predicts cancer prognosis
...s is a very consistent and powerful predictor of a short interval to disease recurrence, metastasis, and death after therapy in cancer patients diagnosed with ten distinct types of cancer. This work indicates that the presence of the conserved BMI-1-associated gene expression pathway that exists in a very...Tiny avalanche photodiodes target bioterrorism agents
...s (PMTs) were the only available technology in the short wavelength UV portion of the spectrum capable of this sensitivity. These fragile vacuum tube devices are expensive and bulky, hindering true systems miniaturization. The APD technology may see further use in the deployment of systems for secure batt...NHGRI expands effort to revolutionize sequencing technologies
...ion" Investigators from this group will hybridize short DNA probes to genomic DNA fragments to determine sequence information. In addition, they will use optical mapping to create restriction maps to help assemble the genome once it is sequenced. The group will then demonstrate how to combine the sequence...Scientists get first glimpse at how plants, most animals repair UV-damaged DNA
... never occurred," Zhong said. But even within that short time, there's a danger of the donated electron jumping back to the photolyase enzyme before the repair is done. Zhong's work has revealed how the water in the pocket performs a critical function at this point. When the photolyase enzyme becomes exc...Tiny roundworm's telomeres help scientists to tease apart different types of aging
... moves with a youthful spring in its crawl despite short telomeres, they report in PLoS Genetics, available...me. When these cells' telomeres reach a critically short length, however, they can no longer replicate. The cell's structure and function begin to fail as it...NIEHS launches website with information for assessing environmental hazards from Hurricane Katrina
... and medical facilities, that will help assess the short and long effects of Katrina on the Gulf region. "With a disaster of this magnitude, people need many things, including easy access to science based information so they can make informed decisions to further reduce their risk of harm," said NIEHS Di...FDA approves child-friendly AIDS medicine
... and medical facilities, that will help assess the short and long effects of Katrina on the Gulf region. "With a disaster of this magnitude, people need many things, including easy access to science based information so they can make informed decisions to further reduce their risk of harm," said NIEHS Di...Research casts doubt on circulating stem cells
... green-fluorescent thanks to a genetic addition. A short time later they then discovered green-fluorescent nerve cells in the mice's brains. This appeared to them to be evidence that the stem cells circulating in the blood could actually transform themselves into nerve tissue. It looked like the discovery ...Researchers find Amchitka seafood safe for now
...ted by the fact that we were able, within the very short single season of work, to add so significantly to the geophysical understanding of Amchitka and its marine environment. I worked with excellent teams from four good research universities." David Kosson, head of the CRESP Remediation Center of Experti...MicroRNAs have shaped the evolution of the majority of mammalian genes
...int for making a protein. A microRNA can bind to a short sequence on a targeted mRNA and suppress protein p...s. Nearly all genes, the authors explain, contain short sequences that match portions of microRNAs. Some of these potential microRNA target sites are evolut...Solexa and collaborating scientists illuminate the small RNA component of the transcriptome
...cience Foundation, generated more than two million short DNA sequences, known as signature sequences or sequence tags, to identify and quantify both known and novel small RNA molecules. Many regions of the Arabidopsis genome previously considered to be inactive or featureless were found to be sites of cons...HIV inserts into human genome using a DNA-associated protein
...t HIV-infected cells in a patient will have a very short life span, a day or less. "We surmise that this st...s it were, producing lots of viral copies during a short time, so that the virus can maximize production of daughter virions," says Frederic Bushman, PhD, Pr...Chernobyl: The true scale of the accident
...iodine, of great concern after the accident, has a short half-life, and has now decayed away. Strontium and...nion and Southern Europe, but, given the nuclide's short half life, this concern abated quickly. Currently and for the long term, radiocaesium, present in mi...A little telomerase isn't enough
...to 75 percent of their chromosomes had dangerously short telomeres. In an affected grandson, signs of the d...nt of the chromosomes in his cells had dangerously short telomeres. "We know it only takes one critically short telomere to make a cell die, so it's clear t...Researchers offer proof-of-concept for Altered Nuclear Transfer
... technique called RNA interference, or RNAi. Here, short interfering RNA (siRNA) molecules are designed to target an individual gene and disrupt its ability to produce protein. In effect, the gene is shut off. Jaenisch and Meissner designed a particular form of siRNA that shut off this gene in the donor nu...Why Christmas trees are not extinct
...ad not evolved easy-flow valves to make up for the short length of their water pipes or conduits, "it is do...ines. So how did conifers overcome the handicap of short pipes? Scientists already knew that the valves between water pipes or conduits are far different i...2005 AIDS figures released by WHO and UNAIDS
...g epidemics, and prevention programmes are falling short of addressing this overlap. The report shows how s...improving in many other places, it still falls far short in most of sub-Saharan Africa. An accelerated scale-up of services is urgently needed to reduce this...Earliest European Farmers Left Little Genetic Mark On Modern Europe
...g epidemics, and prevention programmes are falling short of addressing this overlap. The report shows how s...improving in many other places, it still falls far short in most of sub-Saharan Africa. An accelerated scale-up of services is urgently needed to reduce this...