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Tag: "short" at biology news

Pulsating ultrasound enhances gene therapy for tumors

High-intensity focused ultrasound emitted in short pulses is a promising, non-invasive procedure for ....A., from the National Institutes of Health (NIH), short pulses of HIFU can be used to prevent exposed tissue from becoming too hot and damaged. Pulsed-HIFU ...

Liposome finding implies electrical effect on cell development

...ns (a fraction of a volt but operating over a very short distance--less than a micron--to produce a field up to one thousand times stronger). In images achieved through optical and scanning electron microscopy, microtubules were observed to immediately form and extend from the phospholipid balloon, like a ...

Transgenic plants remove more selenium from polluted soil than wild plants, new tests show

... as a soil amendment in areas where selenium is in short supply. "There are many areas where selenium is deficient, so farmers actually pay for animal feed that is supplemented with selenium," said Terry. "Farmers would love to have this source of selenium." Other co-authors of the study include Danika L...

Gene Therapy Cures Inherited Liver Disease In Rats

...xicity is possible. We need to find a way to avoid short term toxicity." ...

Anti cancer virotherapy well tolerated in first human administration, research finds

...erial which then reproduces at a rapid rate over a short period of time, devouring the cancer cells in the process by attaching to the cells' ICAM-1 (intercellular adhesion molecule-1) and DAF (decay accelerating factor). This CVA21 technology which has been identified by Professor Shafren and his team to...

Silence the gene, save the cell: RNA interference as promising therapy for ALS

.... To trigger RNA interference and silence a gene, short bits of double-stranded RNA are introduced in the cell, where they bind with matching sections of messenger RNA. The cell identifies the resulting messenger RNA strand as faulty and chops it up. As a result, the genetic blueprint isn't delivered and ...

White Blood Cell 'Waste Disposal' System Plays Critical Regulatory Role

...lly harmful foreign substances. Neutrophils have a short lifespan and often die via a programmed cell death pathway called apoptosis within a matter of hours. Dying neutrophils are recognized and ingested by cells in the body tissues called phagocytes. Although the specific mechanisms that regulate the pr...

Used in a new way, RNA interference permanently silences key breast cancer gene

...signed long-acting small interfering RNA (termed a short hairpin RNA, shRNA) for mouse STAT3 into a mouse breast cancer cell line. They chose STAT3 because when activated, it is involved in the formation of multiple types of tumors, including breast cancer. When hijacked by a cancer cell, the activated gen...

New tumor-suppressor gene discovered

...tudy the mutant fly's chromosomes and identified a short segment of DNA on which a mutant gene was most likely to occur. "Genetic techniques helped us to narrow our search for this fly's mutation to a few candidate genes within a very small part of one huge chromosome," Lai explains. The scientists narrowe...

Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression

... would be relatively straightforward. After all, a short stretch of nucleotides like a microRNA should be e... target the mRNA. Given that microRNAs have such a short targeting sequence, they may have broad targeting ability, says Han. Significantly, the researchers...

Biochemists report discovery of structure of major piece of telomerase; implications for cancer

...ral aging process, the telomeres eventually get so short that cells can no longer divide, and they die. While telomerase is turned off in most types of healthy cells in our bodies, it is active in the vast majority of cancer cells, Feigon said. Because cancer cells divide rapidly, their telomeres should g...

Oceans more vulnerable to agricultural runoff than previously thought, study finds

... entire valley is irrigated and fertilized in very short windows of time during a six-month cycle. The excess water from irrigation runs off through streams and channels into the estuaries and then out to sea." Matson and her colleagues wondered if each fertilization and irrigation event would trigger a n...

Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol

...will require that patients be given the drug for a short period of time so that the agent's effect on CDK2 activity can be assessed. In this study, the researchers exposed 10 different human breast cancer cell lines to varied doses of Tarceva and then measured activity of the CDK enzymes. They found that ...

Signs of aging: Scientists evaluate genes associated with longevity

...related diseases." SAGE involves the isolation of short gene-specific sequence tags and provides an unbiased and quantitative measurement of gene-expression differences. This study was the first to utilize SAGE to analyze aging-related gene-expression changes. It is expected that the large volume of SAGE ...

Cellular Defects in Premature Aging Disease are Reversible

...esigned a chemically stable DNA oligonucleotide ?a short DNA sequence that the cell wouldn't be able to degrade ?that would bind to the mutant splice site and prevent the splicing machinery from cutting in the wrong place. "You can think of it as a molecular Band-Aid®," said Misteli. The researchers insert...

Gene therapy cures inherited liver disease in rats

...xicity is possible. We need to find a way to avoid short term toxicity." ### Others who participated in this research include: Drs. Gabriele Toietta, Viraj P. Mane, Milton J. Finegold, Philip Ng, and Arthur L. Beaudet of BCM and Drs. Wilma S. Norona and Antony F. McDonagh of the University of California,...

Scripps scientists find potential for catastrophic shifts in Pacific ecosystems

... make modestly accurate statistical forecasts over short time horizons as shown with certain reef fish (Science 1999)." The paper by the Scripps team helps to clarify the scientific basis of the next decade's challenge for fisheries and ecosystem management. ...

Gene keeps neural cells on correct developmental path

...e study focuses on a protein called REST, which is short for RE1-silencing transcription factor. It was independently discovered 10 years ago by Mandel's group and a second team led by HHMI investigator David J. Anderson at Caltech. Mandel created the acronym to describe how REST quiets the nerve genes. Th...

Retrovirus struck ancestors of chimpanzees and gorillas millions of years ago, but did not affect ancestral humans

...ility of rare genetic variants becoming fixed in a short time. Before long, a genetically disparate population, possibly with wide variations in morphology, would have emerged, leading to today's chimps and gorillas. The study's lead authors are Zhaoshi Jiang, a Ph.D. student in Eichler's lab at the UW, a...

Alcohol consumption disrupts breastfeeding hormones

...on and her milk production will be affected in the short term." ### ABOUT MONELL: The Monell Chemical Senses Center is a nonprofit basic research institute based in Philadelphia, Pennsylvania. For 35 years, Monell has been the nation's leading research center focused on understanding the senses of smell,...

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