Infectious disease expert warns of spread of Rocky Mountain spotted fever
...apidly, causing inflammation of the blood vessels, shock and the build-up of fluid inside the lungs and brain. The precise origins of Rocky Mountain spotted fever are not known, but the disease is only known to occur in North and South America. ...Environmental lessons from tsunami as world's coastal population doubles
...lthy ecosystems are much more likely to absorb the shock and provide protection from a coastal disaster than man-made structures such as sea walls or artificial reefs. Globally 23 per cent of the world's population (1.2 billion people) live within 100 km of the coast and this figure is likely to increase ...Fundamental discovery -- Bone fracture
...an bone." He described the discovery of "molecular shock absorbers" providing a kind of self-healing glue holding biological mineralized structures together when studying the abalone shell six years ago. "It's truly remarkable to find the same fundamental mechanisms operating in bone," said Morse. He note...Elevated temperature enhances success of viral cancer therapy
...5 replication. Interestingly, when a cellular heat shock response was induced in the resistant tumor cells,...ion was restored. Therefore, induction of the heat shock response could rescue ONYX-015 replication in resistant tumor cells. According to Dr. O'Shea, "Our ...Researchers report new pro-inflammatory role for anti-inflammatory enzyme
...g. Sustained overproduction of NO can cause septic shock (sepsis). "In sepsis, which is a systemic bacteria...y may eventually lead to new treatments for septic shock and other inflammatory diseases. "Pharmaceutical companies have been developing iNOS inhibitors to t...WHO Warns Of Increased Risk Of Vector-borne Diseases In Tsunami-affected Areas
...eatment is given promptly, the patient may go into shock and die. * Severe abdominal pains (black stools), bleeding on the skin or from the nose or gums, sweating, cold skin are danger signs. If any one of them is noticed, the patient should be taken to a hospital immediately. * The patient should ...Discovery Promises Simpler Therapy for Sickle Cell Disease
...sorders, including diabetes, heart attacks, septic shock and sickle cell disease. In the current study, the researchers found that hemoglobin in the red cells of patients with sickle cell disease fails to process nitric oxide properly. As a result, they reported, the membranes of sickle red blood cells ar...Scientists solve structure of key protein in innate immune response
...utical companies have tried to develop anti-septic shock agents for a long time without clear success," explains Dr. Lee. "Since LPS is an important inducer of septic shock, blocking LPS receptors such as CD14 are among the most important targets. Our structure shows the shape of the LPS binding pocket of ......e tissue injury occurs. In addition, because toxic shock syndrome is mediated by superantigens, it is possi...e clinical features of purpura fulminans and toxic shock syndrome seen in these patients resulted from massive cytokine release induced by the S. aureus stra...