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Tag: "shield" at biology news

Scientists discover how body fights to control spread of cancer

...red that a large protein, which forms a protective shield around cancer cells and prevents them from causing...ted from causing further disease by the protective shield of a protein called MUC1 in which the cancerous cells are eventually destroyed by our immune system....

Scientists unveil piece of HIV protein that may be key to AIDS vaccine development

...n as conformational masking, which acts to further shield HIV from immune system attack. While the earlier study provided a picture of the CD4-gp120 complex, the new finding delineates the precise stepwise engagement between gp120 and CD4. The researchers found that the gp120-CD4 encounter starts with a ...

Lead with a poisonous electron shield

... pair of the lead cation. It acts as an electronic shield on one side, pushing away the fourth ligand. Such a dramatic geometrical distortion at the active center could explain why lead inhibits this enzyme. The different behavior of lead in these two enzymes demonstrates that it can enter into complexes...

Can engineered immune cells stop AIDS?

...hide from antibodies in a sugar-coated shield. The shield has very few open spaces on its surface, Wang says, which makes it virtually impossible to penetrate. And because the virus also has an uncanny ability to hide, HIV often goes virtually unnoticed by neutralizing antibodies that are roaming the body i...

Manual dishwashing study digs up dirt on dish cleanliness

...ial contaminants. "The prongs of forks actually shield food from the action of scrubbing," Pascall said. "Taking extra time to wash forks is a good idea, especially those covered with sticky foods like cheese." Although cheesy forks were the most problematic utensil, milk dried onto glasses protected ...

Dig deeper to find Martian life

...tively short amount of time. H2O provides an ideal shield of hydrogen to protect life on Mars from destructive cosmic radiation particles. Ice also holds an advantage because it is far easier to drill through than rock. Even here, surviving cells would be out of the reach of current drills. Other ideal site...

An artificial cornea is in sight, thanks to biomimetic hydrogels

...oul," corneas are the panes in those windows. They shield the eye from dust and germs. They also act as the eye's outermost lens, contributing up to 75 percent of the eye's focusing power. On Sept. 11 in San Francisco at the annual meeting of the American Chemical Society, chemical engineer Curtis W. Frank ...

Research links protein to breast-cancer migration

...ancer cells from dying. "Notch proteins appear to shield breast-cancer cells from the body's natural defences and also from being destroyed by chemotherapy," said Dr. Brennan. "This research will help to uncover exactly how Notch proteins have this effect and whether inhibiting their action may be one way...

Molecular force field helps cancer cells defend against attack

...famed starship Enterprise would deploy a deflector shield to evade enemy attack, tumor cells are capable of switching on a molecular force field of their own to fend off treatments aimed at killing them. Now University of Florida researchers have found a chink in their armor. The cells churn out an enzyme ...

Potential vaccine developed for deadly leishmaniasis disease

...stimulate the immune system to deploy a protective shield against disease. "Right now there is a major push to utilize synthetic carbohydrates as antigens in order to control the purity and composition and avoid possible contamination," Seeberger explained. His own group, together with a biotech company ?A...

Penicillin, amoxicillin: Step aside for strep throat treatment

...sulting in a throat full of bacteria that actually shield strep germs from the older drugs. At least four types of bacteria that Pichichero called "co-pathogens" become more dominant in the throat of someone who has received the drugs frequently. It happens in much the same way that the hardened thugs who p...

Ancient immune defense mechanism is no match for HIV-1

...eason that its requirement for an SRS is solely to shield this last 'Achilles' heel that we think HIV-1 cannot alter for functional reasons. The sequence we describe may represent a viable target for RNAi that HIV-1 cannot elude by using the point mutation mechanism, " explains Dr. Jeang. The researchers i...

Gladstone investigators discover how resting T cells avoid HIV infection

...need to determine whether preserving the antiviral shield provided by small A3G in activated and dividing CD4 T-cells does not produce any deleterious effects. These could include the early death of these cells or the creation of mutations in the chromosomes that might lead to cancer. "The possibility of e...

Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma

...o nanoparticles that, in effect, form a protective shield around their precious genetic cargo. These nanopar...aid Hu. "The delivery system we're developing can shield the drugs from degradation before reaching the target sites, while delivering siRNA for more specifi...

Novel antiviral technology inhibits RSV infection in mice

.... The treatment keeps the host's natural antiviral shield intactand attenuates virus reproduction, providing substantial protectionfrom severe infections over days to weeks."Dr. Mohapatra and his team developed nose drops containing vectorscapable of producing small fragments of RNA (siRNA). These fragments...

Dysentery uses 'sword and shield' to cause infection

...ide (LPS) on the surface of the bacteria acts as a shield to protect the dysentery bacterium from being dest...hrough the expression of a molecule that acts as a shield on its surface." The researchers found that shigella, the bacteria causing dysentery uses a Type II...

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