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Tag: "sets" at biology news

A gene's first 'kiss' sets off that affair known as puberty

...adotropin-releasing hormone (GnRH) is secreted and sets off a chain reaction of chemical messages. Inside the hypothalamus, nerve cells release GnRH in a 'round-the-clock,' pulsatile fashion. With each secretion, the pituitary gland is stimulated to secrete its own messengers, lutenizing hormone (LH) and ...

Man and mouse share genome structures

...se unique chromatin structures could be activating sets of HOX genes for specific developmental programs. This global activation may have implications for understanding mechanisms behind certain cancers, Bernstein believes. For example, proteins that place methyl groups on histones can, when mutated, cau...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

...e normal. The tumors grew at the same rate in both sets of mice, suggesting that more tumors get started in the mice with extra IGF2, notes Feinberg. "In the mice, loss of imprinting of IGF2 roughly doubles the risk that the genetic mutation will cause a tumor," says postdoctoral fellow Atsushi Kaneda, P...

Growth in the sea comes down to a struggle for iron

...pens is unclear, but the answer could be that iron sets off a kind of chemical warfare in the marine ecosystem, according to University of Maine oceanographer Mark Wells. And diatoms may not always come out on top. In collaboration with a large Japanese research program, Wells and a team of scientists fr...

Another Look Finds Promising Proteomics Test is Not Biologically Plausible

...rch for a pattern of proteins in blood. In several sets of blinded samples, the test detected all patients...erson researchers examined the quality of the data sets and concluded that this systematic protein pattern “is biologically implausible.?Baggerly explains t...

New species from old data

...rch for a pattern of proteins in blood. In several sets of blinded samples, the test detected all patients...erson researchers examined the quality of the data sets and concluded that this systematic protein pattern “is biologically implausible.?Baggerly explains t...

Cracking the olfactory code in bees

...rch for a pattern of proteins in blood. In several sets of blinded samples, the test detected all patients...erson researchers examined the quality of the data sets and concluded that this systematic protein pattern “is biologically implausible.?Baggerly explains t...

Signaling protein builds bigger, better bones in mice

...rch for a pattern of proteins in blood. In several sets of blinded samples, the test detected all patients...erson researchers examined the quality of the data sets and concluded that this systematic protein pattern “is biologically implausible.?Baggerly explains t...

Finding Cures For Tropical Diseases: Is Open Source An Answer?

...an now identify promising protein targets andsmall sets of chemicals using computation alone."...

Improved Outcomes Releases GeneLinker(TM) Gold and Platinum Version 4.6

... andadvancing the GeneLinker products. The feature sets in either productcannot be matched by any of our competitors at their respective pricepoints," said Radcliffe. "It also demonstrates our commitment toserving user needs--analysis of protein biomarker data, identifyingchannels that statistically disti...

New Clues Add 40,000 Years to Age of Human Species

...0,000 years. No one was able to securely tie both sets of fossils to the same time period. "Fortunately... brief period during which sediments entombed both sets of bones. Together, the various lines of evidence seem to constrain the dates of the fossil human r...

New research questions basic tenet of neuron function

...esicles. "The functional differences of these two sets of vesicles may be the result of differences in th...olution analysis is needed to test whether the two sets of vesicles are indeed distinct." Dr. Kavalali said that if the two types of vesicles have differen...

An entropy-based gene selection method for cancer classification using microarray data

... The algorithm was applied to three different data sets and the results obtained were compared to work done by others using the same data sets. This study presents an entropy-based iterative algorithm for selecting genes from microarray data that are able to classify various cancer sub-types with high ac...

Scientists document complex genomic events leading to the birth of new genes

...ers, the RGP gene cluster may help to explain what sets apart humans and other primates from the rest of the animal kingdom. Human chromosome 2 has always intrigued primate biologists; it formed from the fusion of two mid-sized ape chromosomes and is the only cytogenetic distinction separating humans fr...

PANTHER Protein Classification System Database 5.0

... allows life scientists to browse or analyze large sets ofgenes by their known or inferred biological functions and explore morethan 60 pathways associated with protein families, subfamilies, andtraining sequences using diagrams drawn by expert curators.The new PANTHER system Pathway Module is the result ...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

... to the initiation of tumor formation. This study sets a new paradigm for gastrointestinal tumorigenesis, in that genetic events outside the epithelial layer itself have a profound effect on tumor initiation. Thus it appears likely that this study will foster additional research into other mesenchymal ge...

Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin

...different wavelengths of near-infrared light. This sets the stage for using emissive polymersomes to target multiple cancer cell-surface markers in the body simultaneously. Emissive polymersomes perform much like in vivo imaging systems that use semiconductor-based "quantum dots." These quantum dots, how...

Opposing fat metabolism pathways triggered by a single gene

...colleagues show that in its normal actions, nhr-49 sets in motion two opposing pathways: it increases expression of a gene acs-2, which leads to reduction of fat content, and it increases expression of another gene fat-7, which, by reducing acs-2, increases fat content. In its function, nhr-49 resembles a...

Effective Cancer Treatments Follow The Clock

...circadian clock. We have already started screening sets of chemical compounds for their ability to affect this function. We are also planning additional studies to discover the molecular signals from the circadian machinery to the immune system that might prove to be useful drug targets.?/p>...

Researchers devise way to mass-produce embryonic stem cells

...te without prompting. Yang and Ouyang tested both sets of cells ?the ones grown in a flask and those grown in the bioreactor ?for two key proteins. The presence of these proteins indicates that a stem cell has not differentiated. In the bioreactor experiment, 94 percent of the stem cells tested positive ...

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