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Timing is everything: First step in protein building revealed

...leased from the ribosome, or thatits release might serve an important purpose, so this was a completelyunexpected result," says graduate student David Maag, first author ofthe paper."It's impossible to know for sure whether eIF1 is released completelyin living creatures, but in our laboratory experiments t...

In the sea slug's defense against lobsters, confusion is key

... of spiny lobsters and that indeed these chemicals serve to activate nervous-system pathways that control feeding behaviors of the lobster. The inky secretion also stimulates other behaviors in the lobster, including grooming and avoidance. Ironically, the slug's ability to trick the lobster's nervous syst...

Vital step in cellular migration described by UCSD medical researchers

...nds protrusions out of the cell. These protrusions serve as tractor sites for migration as the cell moves toward its intended target. If Rac were active throughout the cell, it would extend protrusions in all directions, in essence keeping the cell in one place. Until now, researchers have had limited und...

Tiny scaffolding allows stem cells to become working fat cells

... this work might be creating new tissue that could serve either as a temporary substitute while waiting for a donor organ, or even providing a replacement organ." Along with Xihai Kang and Yubing Xie, both postdoctoral fellows in his laboratory, Kniss built a fabric-like carpet of polyethylene terephathal...

RNA project to create language for scientists worldwide

...ategies." As principal investigator, Leontis will serve as coordinator of the consortium, which includes scientists from the United States, Great Britain, France, Canada and Australia. Participating are leading researchers from Stanford, Duke, Yale, Rutgers and Georgia Tech universities, the University of...

UCSD team discovers specialized, rare heart stem cells in newborns

...nction when placed in the intact heart, they might serve as biological pacemakers for infants born with heart block, which could also be valuable." After the isl1+ cells were found in newborn rats, the UCSD team used sophisticated genetic methods to tag the progenitor cells in living embryonic tissue and ...

Measuring the impact of post-genomics on Mediterranean populations

...s went onto to explore which mechanisms would best serve Euro-Mediterranean partnerships in the health research domain. The workshop also laid the groundwork for networks of potential partners to meet and discuss project ideas they could submit in answer to the December 2004 call for proposals under the IN...

DuPont's first biologically derived polymer receives global recognition

...er for the resource consumption of humans and will serve to further protect the environment." DuPontTM Sorona® offers unique properties to consumers and manufacturers. Consumers appreciate the unique qualities that DuPontTM Sorona® brings to fabrics, including exceptional softness, easy care, and UV- and ...

New online portal merges vast data on Gulf of Maine ecosystem

..., or nwolff@usm.maine.edu) The Dynamic Atlas will serve as a pilot for a truly integrated ocean observing system, called the Gulf of Maine Biogeographic Information System. Over time the Census of Marine Life will work with the Gulf of Maine Ocean Data Partnership to take the Atlas and other portals (incl...

Discovery Promises Simpler Therapy for Sickle Cell Disease

...ies that restore nitric oxide to blood cells might serve as a useful method for treating the disease, said HHMI researcher Jonathan Stamler, M.D., professor of pulmonary medicine and cardiology at Duke University Medical Center. The researchers reported their findings on Jan. 31, 2005, in an early edition...

Nanoscale Diagnostic Sets Sights on Alzheimer's

...ounded by hundreds of identical DNA strands, which serve as hundreds of "bio-bar-codes" the researchers can detect at the end of the test. Ultimately, the gold-DNA particles and magnetic particles sandwich the biomarker targets. A magnet separates the sandwich complexes from the rest of the sample. The co...

Stopping smallpox in its tracks: A new anti-viral approach

...itutes of Health point out that this approach "may serve to turn the tables on the virus by interfering with the very pathways that are required for viral replication and extrusion." This study demonstrates, for the first time, that chemical inhibition of host cell signaling pathways exploited by infectio...

Emergence of cancer as major cause of childhood death in developing countries is not being adequately addressed

... “We’ve found that recruiting local oncologists to serve as program directors gives the best results,?Ribeiro said. “The recruited oncologists serve as program directors, advocates of pediatric oncology units and coordinators of training for essenti...

Turning viruses into allies against cancer

...trate the high potential of this modified virus to serve as a novel vector for cancer gene therapy of hepatocellular carcinoma," said Boris Blechacz, M.D., a research fellow in the Molecular Medicine Program at the Mayo Clinic and the study's lead investigator. Liver cancer is one of the leading causes of...

Africa to take it on chin again with climate change

...oving west from the Sahel during the monsoon often serve as seed for tropical storms and hurricanes in the North Atlantic. Hurrell's work does not address the possible impact of increased rains in the Sahel on future Atlantic hurricane activity. For their study, Hurrell and Hoerling examined output from c...

Marine sponge yields nanoscale secrets

...iscovery. Never before had a protein been found to serve as a catalyst to promote chemical reactions to form the glass or a rock-like material of a biomineral. From that discovery, the researchers learned that this enzyme actively promotes the formation of the glass while simultaneously serving as a templa...

Norovirus found to cause traveler's diarrhea

...to identify Norovirus-positive stool samples could serve to facilitate future Norovirus-related research in developing countries. "Prevalence of Norovirus among U.S. Visitors to Mexico and Guatemala Experiencing Traveler's Diarrhea" was supported by a grant from the Center for a Livable Future at the John...

Product improves peptide identification for proteomics research

... chemical analysis. The company's 28,000 employees serve customers in more than 110 countries. Agilent had net revenue of $7.2 billion in fiscal year 2004. Information about Agilent is available on the Web at www.agilent.com. ...

Conserved amino acids play both structural and mechanistic roles in sandwich-like protein

...zing the final structure of the protein, and three serve to direct the process of protein folding. "We directly demonstrated that in one protein within the large sandwich-like protein family, evolution has indeed preserved amino acids for mechanical reasons," Wittung-Stafshede said. "We believe that our d...

wFleaBase: the Daphnia genome database

...karyote genes of known function. wFleaBase aims to serve a large ecological and evolutionary research community. Our challenge is to rapidly expand its content and to ultimately integrate genetic and functional genomic information with population-level responses to environmental challenges. ...

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