Animal models show that anabolic steroids flip the adolescent brain's switch for aggression
...g other new findings, as yet unpublished, that the serotonin system ?implicated in depression ?may never recover. "If you hit the right areas of the brain at the right time, you make permanent changes," Melloni concludes from the converging evidence. He hopes that adolescents don't take the ultimate re...Worms know bad food when they smell it
...'I've gotten sick,'" Bargmann said. The role of serotonin suggests that this type of learning may be a parti...el, Bargmann said. In humans, the vast majority of serotonin is produced by cells in the intestine, where its release can generate nausea such as that associated...Gene variation affects tamoxifen's benefit for breast cancer
...sant drug Effexor does not. These drugs, selective serotonin reuptake inhibitors or SSRI's, are often used to treat hot flashes, a common side effect of tamoxifen. In this current study of 256 women with breast cancer, researchers also found that women with the CYP2D6 variant were less likely to have hot flas...Researchers show how air pollution can cause heart disease
..., the researchers tested how the neurotransmitters serotonin and acetylcholine affected the aortic arches of PM...ontrol group, constricting more in the presence of serotonin and relaxing less in response to acetylcholine. Once again, the mice fed high-fat diets suffered the...Gambling monkeys give insight into neural machinery of risk
...people who have low levels of the neurotransmitter serotonin might be more risk prone and impulsive," said Plat...ion. We can do pharmacological manipulation of the serotonin system in monkeys to see how it influences risk perception and risk preferences, and whether we see ...Tetanus toxin found to have therapeutic properties
...riments have shown that the harmless part inhibits serotonin from being transported through the synaptic membra...ks by selectively inhibiting the transportation of serotonin in the nerve endings. Behavioural disorders such as depression, anxiety and anorexia may be treated ...Depression gene may weaken mood-regulating circuit
...he depression-linked gene. The gene codes for the serotonin transporter, the protein in brain cells that recyc..., resulting in less recycling, increased levels of serotonin in the synapse, and more serotonin-triggered cellular activity. Previous NIMH-supported studies had ...Second messenger NAADP shows fast, dose-related impact on satiety cycle
...osen because they released a chemical ?the hormone serotonin -- in the brain that controls satiation, as well as mood and body temperature. "More recently, another hormone, cholecystokinin, has been considered to be a potential drug target," Yamasaki noted. Cholecystokinin is a naturally-occurring chemical syn...The circadian clock: Understanding nature's timepiece
...involves resetting the circadian clock by altering serotonin levels, the same neurotransmitter that the anti-depressant Prozac targets. He says it could one day be possible to move people ahead eight hours simply with a pill and light therapy. All terrestrial organisms ?even single-celled organisms ?have circ...Brain-injury rehabilitation depends on acetylcholine circuitry
...urotransmitters such as noradrenalin, dopamine, or serotonin have also been implicated in cortical plasticity and may also be manipulated to aid recovery after such injury. Publishing in Neuron, Volume 46, Number 2, April 21, 2005, pages 173?79. http://www.neuron.org ...