Oldest fossil human protein ever sequenced
...pens up the exciting possibility of extracting and sequencing protein from other fossils, including earlier humans, as a means of determining the relationships between extinct and living species, and to better understand the phylogenetic relationships. ...Marine sponge yields nanoscale secrets
...trols the synthesis of the needles. By cloning and sequencing the DNA of the gene that codes for this protein, they found that the protein is an enzyme that acts as a catalyst –?a surprising discovery. Never before had a protein been found to serve as a catalyst to promote chemical reactions to form the glass o...Study reveals new technique for fingerprinting environmental samples
...f the journal Science positions large-scale genome sequencing to accelerate advances in environmental sciences akin to the contributions DNA sequencing has made to biomedical sciences. "These DNA sequence fingerprints can be used to provide highly acc...Disease diagnosis, biodefense among UH chemical research projects
...laced by molecular biology-based methods as genome sequencing advances. This work presents novel DNA-sequence-ba...s important in diagnosing genetic diseases, genome sequencing and making DNA-based vaccines for diseases like Ebola and HIV. ### For more information about the ...Researchers uncover sequence of major rice pathogen
...me lifted the veil from a fungal plant pathogen by sequencing the genome ?or set of all genes ?of the most destructive enemy of rice: Magnaporthe grisea, the fungus that causes rice blast disease. Dr. Ralph Dean, professor of plant pathology and director of North Carolina State University's Center for Integrat...New lab technique identifies high levels of pathogens in therapy pool
A research team using a novel genetic cloning and sequencing technique has identified a surprisingly high numbe...a ribosomal RNA analysis that involved cloning and sequencing genes. The team concluded that the microbes, many of them pathogenic, were enriched just inches abov...HIV-1 spread through six transmission lines in the UK
...lable since the introduction of routine HIV-1 gene sequencing for drug resistance. Scientists used this data to follow the changing number of infected individuals through time and estimate the demographic parameters shaping the epidemic. During the exponential growth phase, the transmission chains had an avera...Researchers develop rapid diagnostic tool for pathogen identification
...uences and on a technology previously used for DNA sequencing and detection of genetic polymorphisms. Genetic probes for pathogens were coupled to markers known as mass codes. After amplification, incorporated mass codes were detected by mass spectroscopy allowing identification of the pathogen. According to T...Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits
...natomic features. Beginning in the late-1970s, DNA sequencing technology permitted biologists to identify the precise subunit sequence of every gene in the genomes of everything from malaria pathogens and mosquitoes to mouse and human. Databases of genomic information have been combined with databases that list...Octopuses occasionally stroll around on two arms, UC Berkeley biologists report
...sed whenever the low armor trait evolves. "We used sequencing studies to compare the molecular basis of this trait across the northern hemisphere," said Kingsley. "It doesn't matter where we look, on the Pacific coast, the East coast, in Iceland, everywhere. When these fish evolve this low-armored state they ar...Scientists reveal molecular secrets of the malaria parasite
...sociate Investigator Jane Carlton, who had led the sequencing of P.yoelii. At TIGR, Carlton constructed a composite of all three rodentgenome sequences (P. yoelii, P. berghei, P. chabaudi) by aligning themagainst the P. falciparum genome to create a whole-genome synteny mapof the four species. In collaboration ...Researchers trace evolution to relatively simple genetic changes
...sed whenever the low armor trait evolves. "We used sequencing studies to compare the molecular basis of this trait across the northern hemisphere," said Kingsley. "It doesn't matter where we look, on the Pacific coast, the East coast, in Iceland, everywhere. When these fish evolve this low-armored state they ar...Enzyme shown to help protect genomic stability
...sing attention from scientists as they move beyond sequencing the human genome to trying to better understand how DNA is managed and its activity regulated. Histones are small proteins around which DNA is coiled to create structures called nucleosomes. Compact strings of nucleosomes, then, form into chromatin, ...Color-blind method opens new doors in DNA sequencing
...niversity could open new doors that would take DNA sequencing to the patient's bedside, the doctor's office and ...ant professor of chemistry at Rice. "We could make sequencing portable and do it faster." The research appears this week in the journal Proceedings of the Nation...Found: Missing sequence of the human Y chromosome
...e of GenomeResearch (www.genome.org), presents the sequencing and analysis of 554kilobases of previously uncharacterized sequence from thepericentromeric region of the Y chromosome. This sequence contains a450-kilobase "euchromatic island" with eight presumably active genesflanked by repetitive satellite sequen...Learning to fight an adversary that won't stay down
...antibiotic resistance. Techniques such as genomic sequencing and high throughput screening were expected to make the development of new antibiotic compounds easier and more productive. But in most cases the microbes continue to hold the upper hand ?and if three billion years of bacterial history is any kind of...Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
...caused by E. histolytica is called amebiasis. The sequencing of E. histolytica was a collaborative effort led by The Institute for Genomic Research (TIGR) in Rockville, MD, and by the Wellcome Trust Sanger Institute in the U.K. The project was supported by grants from the National Institute of Allergy and Infe......g a study to develop new approaches for isolating, sequencing and analyzing the genomes of "friendly" bacteria t...to translate the genetic data obtained from genome sequencing projects to allow researchers to better understand the evolution and diversity of life on Earth, as ...