sequences 2 6

Tag: "sequences" at biology news

HIV inserts into human genome using a DNA-associated protein

...rs are often used to introduce therapeutic genetic sequences into human chromosomes, such as in the delivery of...me could help make the delivery of new therapeutic sequences safer. The new findings about LEDGF suggest that engineered tethering interactions might some day al...

Cornell finds natural selection in humans

...n 39 humans and a chimpanzee. By comparing the DNA sequences of the 39 human subjects across the 20,000 genes, the Celera researchers identified DNA sites in the genome where individuals in the sample differed from one another. The chimpanzee sequence was then used to identify which form of the gene was the or...

Mammalian Transcriptome Mapped

...er of different regulatory roles, and now that the sequences of these noncoding RNA molecules are known, scient...'s still unclear whether the majority of antisense sequences are involved in regulation or in some other biology, he adds, but this result is likely to fuel rese...

New amphibian species result from exploration, not from rule changes

...mes from the 19th century to the present. The gene sequences were no more similar in recently recognized species than in long-recognized species, a result that argues again taxonomic inflation as the explanation for the growth. Moreover, the Mantellidae include few subspecies that could complicate an analysis....

Embryonic stem cells accrue genetic changes

...obing changes in the nuclear and mitochondrial DNA sequences and copy numbers, the researchers examined whether the cells' genetic material had shifts in marks that sit on genes and are passed from cell to cell during cell division. These so-called epigenetic marks -- in this case methyl groups on a gene regio...

Delaware scientists make significant advance in study of small RNAs

...ified from diverse plant and animal systems, these sequences were identified using older technologies that do n...e identified." In addition to the sheer number of sequences identified, Meyers said "the biggest surprise in the findings is the diversity." He said that their ...

New possibilities for flu antiviral and vaccine research emerge from 'Spanish flu' virus

...everse genetics," which involves transferring gene sequences of viral RNA into bacteria and then inserting comb... Forces Institute of Pathology provided the coding sequences for the eight Spanish flu genes to Christopher Basler, Peter Palese, Adolfo Garcí¡­Sastre and their co...

First big influenza genome study reveals flu evolution

...en vaccine works," Ghedin notes. She adds that all sequences described in the current study have been deposited in public databases, such as GenBank, which allows immediate access to the scientific community. The new study represents the initial results from the Influenza Genome Sequencing Project, launched i...

Ancient trans-Atlantic swarm brought locusts to the New World

... Lovejoy and his colleagues used mitochondrial DNA sequences to reconstruct the evolutionary history of the Schistocerca locusts. The team found that the desert locust lineage gave rise to the more than 50 Schistocerca species found in the western hemisphere. ...

Same-sex mating by fungi spawned infection outbreak, evidence suggests

... the other five percent. By comparing select gene sequences that spanned the genomes of the Vancouver Island fungi to samples collected from around the world, the team traced the rarer type to identical isolates in Australia. The major form matched a sample taken from an infected person in Seattle 30 years ag...

Yale participates in global human genome initiative

..., gene families and metabolic pathways. The siRNA sequences have blueprints in DNA and are transcribed, but not translated into proteins. Researchers have recently found that several siRNAs regulate critical gene functions in normal development and in development of cancer. "Participation in this consortium...

Key brain regulatory gene shows evolution in humans

...also found an "evolution-by-association," in which sequences near the regulatory segment showed greater mutatio...ionary selection when they compared the regulatory sequences in people from different populations -- including those from Cameroon, China, Ethiopia, India, Italy...

Many needles, many haystacks

...motifs. Then it was up to the computer to scan the sequences for small patterns. The attempt was successful: in the fly data, for example, 26 sets of proteins seemed to be interacting through linear motifs. "One challenge was to eliminate red herrings, which crop up everywhere when you look for very small pat...

Scientists sequence DNA of woolly mammoth

...any. The researchers' report on the first genomic sequences from a woolly mammoth will be published on 22 December 2005 by the journal Science on the Science Express website, http://www.sciencexpress.org . This majestic mammal roamed grassy plains of the Northern Hemisphere until it became extinct about 10,...

Scientist uses form to explain function of key building blocks of life

...r. "Variants of rubredoxin have evolved different sequences to transport electrons in the most efficient manner possible," Markley explains. "Different mechanisms have been put forward to explain this, and we wanted to understand how the proteins evolved to have different electron affinities." Markley and h...

The bioweapon is in the post

... and deadly pathogens. Customers typically submit sequences by email or via a form available on a company's we...earch, to ask whether they screened orders for DNA sequences that might pose a bioterror threat. Of the 12 companies that replied, just five said they screen eve...

New methods offer insight into regulatory DNA

...ith diabetes and obesity. In comparison with gene sequences that contain the instructions to make proteins, re...ols are needed in the search of our genome for the sequences that contribute to disease, tools that will harness the massive amounts of DNA information and trans...

Common viruses may cause cancer

...s (for example, endogenous retroviruses, whose DNA sequences comprise at least 8% of the human genome) might contribute to cancer remain to be determined. In addition to revealing that common viruses might contribute to cancer by fusing cells, the researchers report that the use of fusogenic viruses as vecto...

New U. of Colorado at Boulder flu chip may help combat future epidemics, pandemics

...nsfer Office and plan to make the Flu Chip genetic sequences freely available to interested researchers. There currently are less than 200 facilities worldwide that provide detailed strain analysis of influenza, said Rowlen. Strain identification is critical for tracking emerging strains and in determining w...

New research examines genetics of successful aging

...search team attempted to identify specific genetic sequences present in older individuals that may be linked to...gnitive abilities, or conversely, specific genetic sequences present in younger individuals (and not present in those over age 90) that may impede successful agi...

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