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Tag: "sequence" at biology news

Scientists solve 30-year-old mystery of mutant mouse's kidney woes

...nephrosis. With assistance from the mouse genome sequence and Li Ding, Ph.D., a research instructor at the G... not just a result of the problem, we analyzed the sequence of the aqp2 gene from the mutant mice, comparing it to the gene from other normal mice, and found a ...

Rhesus monkeys in Nepal may provide new alternative for HIV/AIDS research

...inese-origin rhesus macaques. The researchers did sequence analyses of mitochondrial DNA and examined the distribution of certain types of alleles, or pairs of genes, for genetic variations distributed across 17 chromosomes. They also looked for the presence of other alleles that are known to influence immun...

Scientists' cell discovery unearths evolutionary clues

...ms in the USA and Germany, have won sponsorship to sequence the genomes of social amoeba species identified by the work in York and Dundee. ...

Researchers find that bumblebees' flower choice matters

... one bee at a time, calling out its exact foraging sequence by number to her undergraduate assistant, Dustin Knutowski, who charts the path. In the time she has spent working at the garden, she says, the invader plant is the heavier "bee magnet." And if that's the case, purple loosestrife is luring pollinat...

Scientists resuscitate a 5 million-year-old retrovirus

A team of scientists has reconstructed the DNA sequence of a 5-million-year-old retrovirus and shown that ...structed a retrovirus--Phoenix--from the consensus sequence by mutating existing HERV-K(HML2) copies. In addition, the researchers showed that Phoenix coul...

Gut reaction: Researchers define the colon's genome

...e samples, generating a total of 65,059 and 74,462 sequence reads, respectively, from the two subjects. They f...o much of the microbiome residents. Based on the sequence comparisons, the researchers conclude that the human GI tract hosts multiple strains of B. longum ,...

Mobile DNA part of evolution's toolbox

...the first author of the study. Close copies of the sequence were ubiquitous in amphibians, birds, and mammals,...m frogs to humans," says Bejerano. Comparing the sequence to other species also turned up a big surprise. When the researchers compared the human ultraconserv...

Unique soybean lines hold promise for producing allergy-free soybeans

...here was a single significant change in the gene's sequence that likely produced a protein which could not be made as a stable product." Herman discovered P34 in the early 1990s and in 2003 had successfully used a gene-silencing technique to create a soybean line in which P34 was "knocked out." However, beca...

Study provides first look at the 'birth' of a retina cell

...creating a mouse model using an NRL regulatory DNA sequence to produce a protein that appears as fluorescent green when exposed to blue light. This fluorescent protein allows scientists to identify even a few cells that are destined to be rods at very early stages of development. "For the first time we were ...

Surprising symbiosis: Glassy-winged sharpshooter eats with friends

...orensic samples of DNA sequences, removing all the sequence reads that matched neither the insect nor its known symbiotic B. cicadellinicola bacteria. A large amount of the leftover DNA mapped to another bacterium, S. muelleri. Sure enough, when they pooled the bits of sample DNA that came from S. muelleri, t...

Interfering RNA silences genes in 'slippery' immune cells

...archers insert a payload of DNA. The DNA holds a sequence of genetic code that produces a specific siRNA after it enters a nucleus. The researchers encased the DNA within an siRNA expression cassette (SEC), an inexpensive, quickly synthesized product that carries genetic sequences to regulate the gene activ...

Origen publishes in Nature a robust and versatile method for creating transgenic chickens

...f the chicken immune system to produce novel human sequence polyclonal antibodies. Moreover, the new technolog...ed in Nature Biotechnology the production of human sequence monoclonal antibodies having greatly enhanced cancer killing activity compared to antibodies produce...

Large-scale genomics project will hunt genes behind common childhood diseases

...diseases." The Human Genome Project compiled the sequence of DNA bases in all 23 chromosomes in the human genome, while the HapMap Project listed haplotypes ?blocks of DNA sequences with variations thought to be linked to risks of specific diseases. Leading the new Center for Applied Genomics is Hakon Hakon...

Massive duplication of genes may solve Darwin's 'abominable mystery' about flowering plants

...mber of plant species for which only a partial DNA sequence has been determined. The team uncovered evidence ...ependent mutation. Most mutations in a gene's DNA sequence cause a change in the corresponding gene product. But "synonymous" mutations in DNA do not lead to ...

The Midas Bug -- the bacterial alchemy of gold

... DNA-positive gold grains from both locations. DNA sequence analysis of this species identified it as the bacterium Ralstonia metallidurans. "The next step was to see if we could observe gold precipitation in the presence of a culture of this bacteria," Dr Reith said. "By placing a culture of the R. metal...

Discovery could aid fight against cystic fibrosis infection

...air John Mekalanos, recognized that the amino acid sequence of Hcp1 in PA closely resembled that of Hcp1 in Vibrio cholerae. The Mekalanos lab had previously discovered that the Hcp1 protein of V. cholerae is released from the bacterium via a novel secretion pathway. Because Hcp1 proteins from both pathogens...

Biologists find regions of rice domestication

...ir collaborators from Taiwan have examined the DNA sequence family trees of rice varieties and have determined that the crop was domesticated independently at least twice in various Asian locales. Jason Londo, Washington University in Arts & Sciences biology doctoral candidate, and his adviser, Barbara A...

UCLA study finds same genes act differently in males and females

...ne expression -- the process by which a gene's DNA sequence is converted into cellular proteins. With the help of Rosetta Informatics, the team scrutinized more than 23,000 genes to measure their expression level in male and female tissue. What they found surprised them. While each gene functioned the sam...

DNA to the defense

...of African trypanosomes." Analysis of the genome sequence of T. brucei was published just last year, amid increasing calls for research into new control strategies for this neglected disease. The current study underscores this parasite's reputation as a master of adaptation, devoting unprecedented resour...

Parallel evolution: Proteins do it, too

...pability independently. But at the DNA and protein sequence level, it's very rare to find parallel evolution. ...due to identical amino acid changes at the protein sequence level," Zhang said. "Indeed, we found three amino acid changes that were identical in the two lineag...

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