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Tag: "sequence" at biology news

NHGRI aims to make DNA sequencing faster, more cost effective

...nts developed as part of the successful project to sequence the human genome. However, it still costs around $10 million to sequence 3 billion base pairs ?the amount of DNA found in the genomes of humans and other mammals. NHGRI's n...

Comprehensive model is first to map protein folding at atomic level

...ems in science has been deciphering how amino acid sequence -- a protein's primary structure -- also determines its three-dimensional structure, and through that its biological function. Our paper provides a first solution to the folding problem, for small proteins, at an atomic level of detail." Fiendishl...

Sequencing of the oyster mushroom genome

...o de Lucas, is leading an international project to sequence the genome of the oyster mushroom. The project res...quencing a viable project and they have managed to sequence about 350 thousand "letters" of the genome of this mushroom, corresponding to 1% of the total genome...

Common ancestry of bacterium and plants could be key to an effective new treatment for chlamydia

...udson had discovered was unmistakably similar to a sequence that Anthony Maurelli of the Uniformed Services University of the Health Sciences in Bethesda, Md., had detected in Chlamydia. "Further experimentation confirmed that the Chlamydial gene had the same function as the Arabidopisis gene demonstrating th...

New technique boosts size of proteins that can be analyzed

...in the sequence. The new approach can also provide sequence information on a protein from scratch when it is not present in any database. ...

'GreeneChip' -- New diagnostic tool that rapidly and accurately identifies multiple pathogens

...eneChip features include a comprehensive microbial sequence database that integrates previously distinct reserves of information about pathogens—for every entry of a pathogen and its properties, the GreeneChip contains a correlate of its genetic makeup. GreeneChip performance was initially tested by usin...

Pheromone from mother's milk may rapidly promote learning in newborn mammals

...for survival, and they typically exhibit a defined sequence of actions when searching for milk. This searching behavior rapidly becomes increasingly directed, showing that mammalian newborns are efficient learners. Past studies of this very early learning in the European rabbit (Oryctolagus cuniculus) have sh...

Genetic surprise confirms neglected 70-year-old evolutionary hypothesis

... nature, and it wasn't until we had the ability to sequence whole genomes that we could even attempt to investigate the question." Curiously, the hypothesis nearly died twice. Theodosius Dobzhansky, a well-known evolutionary geneticist, studied fruit flies in the infant days of genetic research in 1930. He ...

Protein splicing upsets the DNA colinearity paradigm

...ies on the direct, linear relationship between the sequence of a protein and the DNA encoding that protein. In...is the faithful transcription of the entire gene's sequence into an RNA sequence. The RNA is then 'spliced' such that the non-coding sequences are removed and t...

Mapping the mouse genome

...dentified "jungles" and "deserts." They looked for sequence motifs that might be representative of jungles and...such as chromosome, chromosomal location, sex, and sequence composition are related to recombination rates--information that can improve our understanding of in...

Scientists win grants to develop $1,000 genome sequencing technology

The current cost to determine the sequence of nucleotide bases in the 6-billion-base-pair hum...per human genome sequenced. Determining the genome sequence of individuals is considered crucial to understanding and routinely treating hundreds of inherited d...

University of Iowa scientists explore function of 'junk DNA'

...n genome. The function of the remaining non-coding sequence is just beginning to be unraveled. In fact, until very recently, much of the non-coding sequence was dismissed as junk DNA. In 1998, scientists discovered that some DNA produced small pieces of non...

Taking 'chips' to the next level of gene hunting

...he TIP-chip highlights exactly where along the DNA sequence these elements have landed. By chopping up the DNA, amplifying the DNA next to the transposable elements and then applying these amplified copies to the TIP chip, the researchers were able to map more than 94 percent of the transposable elements to t...

Inheritance outside DNA

...on of methyl groups"around a gene, but not the DNA sequence itself. These methylation patterns are reprogrammed when passed from generation to generation, carrying instructions related to the parent from whom that copy was inherited but without altering the DNA. Abnormal methylation patterns in cancerous...

Unraveling where chimp and human brains diverge

...ing supports the theory that variations in the DNA sequence contributed to human evolution." Relying on a new analytical approach developed by corresponding author Steve Horvath, UCLA associate professor of human genetics and biostatistics, the UCLA team used data from DNA microarrays ?vast collections of...

Mayo discovers protein as potential tactic to prevent tumors

...genetic code, cells are shunted toward a molecular sequence that leads to death, or apoptosis. Cells have the genetic knowledge to sacrifice themselves for the greater good of the organism rather than to pass on errant genetic codes that can lead to disease. Genetic errors that sneak past the cell's quality c...

Genetic study of Neanderthal DNA reveals early split between humans and Neanderthals

...of Neanderthal DNA. Unlike the libraries used to sequence the human genome, which contained only human DNA f...o confirm that the vast majority of the human-like sequence in the library was indeed Neanderthal and not just contamination from human bone collectors and labo...

Few clues about African ancestry to be found in mitochondrial DNA

...tabase and fewer than 10% were an exact match to a sequence from a single African ethnic group. ...

Motorola researchers develop selective sensors based on carbon nanotubes

... are made of 20 or so amino acids, so changing the sequence of amino acids allows the researchers to "tune the...e of the sensors on biological molecules, like RNA sequence detection, Tao and Forzani said. ...

Biologists probe the machinery of cellular protein factories

...genetic instructions are first copied from the DNA sequence of the gene into a messenger RNA molecule. The rib... are made from amino acid building blocks, and the sequence of amino acids determines the protein's structure. Amino acids are carried to the ribosome by transf...

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