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Tag: "sequence" at biology news

New fruit fly protein illuminates circadian response to light

...examination of the protein produced by the mutated sequence led researchers to JET, a new protein within the F...ag flies by genetically replacing the mutated gene sequence with the normal sequence, which led to the production of the wild-type (control) JET protein. When t...

The loss of a protein favors lung tumor growth

...of different types of lung tumors and introduced a sequence of the protein αCP4 in order to observe the resulting effects. In some of the cells she demonstrated that the tumor proliferation was reduced. In particular, in malignant tumors of large cells she observed that their capacity for growth was reduced, ...

Evolutionary scrap-heap challenge: Antifreeze fish make sense out of junk DNA

... to this because it consists of a short repetitive sequence that only needs to be duplicated four times to give a fully functioning protein". ...

UCR researchers design chip that can improve citrus varieties

...srael for sharing the full content of their citrus sequence data. "Other colleagues in the United States, Japan and Spain who deposited sequences to the public repository maintained by the National Center for Biotechnology Information also made valuable contributions. The use of all available public data res...

Nanopore method could revolutionize genome sequencing

...he feasibility of a fast, inexpensive technique to sequence DNA as it passes through tiny pores. The advance ...of the journal Nano Letters, describes a method to sequence a human genome in a matter of hours at a potentially low cost, by measuring the electrical perturbat...

Study fishes out new role for prostaglandins

...s or orchestrates a myriad of events in the proper sequence (lots of trains)," said Solnica-Krezel, "and sometimes one train wreck can halt the entire process." While 'bad timing' during development can spell the end for an embryo, finding ways to exploit this pathway could have beneficial effects in cancer...

New method for identifying microbes

...g is expensive, so the shorter the section you can sequence and still get useful information, the better," van...e so short, we 'glue' 10 to 30 of them together to sequence all at one time, making this a highly efficient, cost-effective technique." For tag sequences that ...

Study finds 60 new genes controlled by DNA snippet

... Study Details In Miano's study, the regulatory sequence under examination was the CArG box. The nucleotide...A), thymine (T), guanine (G) and cytosine (C). Any sequence of code starting with 2 Cs, followed by any combination of 6 As or Ts, and ending in 2 Gs is a CArG ...

Salmonella bacteria use RNA to assess and adjust magnesium levels

...ria with MgtA genes to see if their DNA included a sequence similar to the riboswitch in Salmonella. In six other bacteria, a similar sequence precedes the MgtA gene and can twist RNA copied from it into different configurations. "Normally y...

New method enables gene disruption in destructive fungal pathogen

...velopment of this protocol is timely as the genome sequence of A. brassicicola is scheduled for completion in ...will allow us to dissect the pathogen's nucleotide sequence information and establish the function of many of the individual genes in this filamentous fungus," ...

Enzyme crystal structure reveals 'unexpected' genome repair functions

...hed DNA in E. coli. These two proteins have little sequence similarity. Biochemical assays following this discovery indicate that this domain allows XPB to interact with damaged DNA and enhances its unwinding activity on damaged DNA." The report suggests that unknown protein and DNA interactions at transcrip...

Finding a virus is not all bad news

...age of cougars you are able to analyse its genetic sequence to learn about the cat population. "Every virus strain has its own unique mutations and as the virus is passed from cougar to cougar these mutations in the virus accumulate, leaving a valuable trail of information about the host animal's relationshi...

Where 'jumping genes' fear to tread

...quirement of 10 or more kilobases of uninterrupted sequence in terms of the current paradigms of transcriptional regulation," explains Mattick. "It appears that TFRs might be the passive signatures of one or more poorly understood mechanisms of gene regulation that operate in higher organisms, suggesting a w...

Most human-chimp differences due to gene regulation ?not genes

...ly in humans, accumulating changes in their coding sequence as well as in expression rates. "Together," they add, "these findings raise the possibility that the function and regulation of transcription factors have been substantially modified in the human lineage." This is a very efficient way to make big ch...

Virginia Bioinformatics Institutes launches microbial database

...cids Research (Vol.34, D379-D381), contains genome sequence and annotation data for the plant pathogens Phytop..., which makes it easy for users to view the genome sequence data and connect to detailed annotation pages for each sequence. The community annotation interface ...

MIT research holds promise for Huntington's treatment

...ght lead to a drug that could help stop the deadly sequence of cellular events that Huntington's unleashes. "Depending on its target, any one compound will probably block only a subset of the pathogenic effects," Bodner said. Huntington's disease is caused by misfolded proteins, called huntingtin proteins, ...

Variation in bitter-taste receptor gene increases risk for alcoholism

...n, Goate's team took advantage of available genome sequence databases to speed work in identifying and studying genes on chromosome 7. She says data from the Human Genome Project allowed the investigators to more quickly recognize individual variations in genes, called polymorphisms, that can influence how a ...

MBL leads effort to update E. coli genome

...based on previously known experimental evidence or sequence analysis. "We cooperated to an amazing extent, reviewing every single one of 4,500 genes of E. coli K-12," said Riley. The scientists developed the best consensus on the status and properties of each of the E.coli K-12 genes at the present moment. ...

Unraveling the mysteries of poison

...fective when it recognises a particular amino acid sequence in the ion channel. It is also important how intrinsically flexible the binding partner is; for a strong interaction to take place, the molecules of both partners have to be able to change their structures. Applying these new spectroscopic methods, ...

High resolution 'snapshots' detail dynamics of a cocaine antibody

... catalytic reaction, we have shed new light on the sequence of events in an antibody-mediated reaction and provided a rare glimpse of the structural dynamics involved. With this information, it's possible to move onto the next step in the development of a treatment for cocaine abuse and addiction." ...

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