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Tag: "septic" at biology news

Scientists solve structure of key protein in innate immune response

...lso lead to the development of drugs to help treat septic shock, an often fatal systemic bacterial infection...ins Dr. Lee. "Since LPS is an important inducer of septic shock, blocking LPS receptors such as CD14 are among the most important targets. Our structure shows...

Discovery Promises Simpler Therapy for Sickle Cell Disease

...many disorders, including diabetes, heart attacks, septic shock and sickle cell disease. In the current study, the researchers found that hemoglobin in the red cells of patients with sickle cell disease fails to process nitric oxide properly. As a result, they reported, the membranes of sickle red blood ce...

Researchers report new pro-inflammatory role for anti-inflammatory enzyme

...ad thing. Sustained overproduction of NO can cause septic shock (sepsis). "In sepsis, which is a systemic ba...iscovery may eventually lead to new treatments for septic shock and other inflammatory diseases. "Pharmaceutical companies have been developing iNOS inhibitor...

Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression

... that underlie many diseases, including cancer and septic shock. The discovery concerns tiny fragments of R...exactly what happens when people are stricken with septic shock. Likewise, the loss of control of genetic expression is the underlying cause of various forms ...

Molecular research suggest shift needed in how some drugs are created

...response can set the stage for various infections, septic shock and numerous autoimmune disorders. Since researchers at the University of Texas Southwestern in Dallas and the Howard Hughes Medical Institute reported the structure of Pelle bound to the adapter molecule known as Tube, there has been an effor...

Antibacterial coatings cut infection rates

... bacterial colonisation of implants that result in septic inflammation problems. "We are using molecules called furanones, which are derived from natural chemicals originally extracted from Australian macro algae seaweed that grows off the eastern coast. The chemicals produced by these macro algae were fou...

Infection 'alarm' yields clues to immune system behavior

...tions for immune system-related ailments including septic shock, cancer, lupus and rheumatoid arthritis. Th...es, the result may be a dangerous condition called septic shock.) The innate immune response begins when white blood cells detect a bacterial intruder or tox...

Microbes convert 'Styrofoam? into biodegradable plastic

...olystyrene, it readily breaks down in soil, water, septic systems and backyard composts. Worldwide, more than 14 million metric tons of polystyrene are produced annually, according to the U.S. Environmental Protection Agency. Most of this ends up in landfills. Although polystyrene represents less than 1 pe...

Lack of a key enzyme dramatically increases resistance to sepsis

...e body's "vulnerability to bacterial infection and septic shock" while a deficiency confers strong resistanc...2 deficient mice were resistant to peritonitis and septic shock and were able to clear pathogenic bacteria more efficiently than mice with the enzyme. The pre...

Mayo Clinic researchers challenge sepsis theory

...errupts bacterial poisons, it has no impact on the septic disease. That suggests that perhaps the poisons don't cause sepsis after all," Dr. Platt says. "Problems such as this caused us to ask, 'Could there be something else driving sepsis, other than the classic poisoning explanation?'" Mayo Discovers Ke...

Researches discover gene critical for protection against septic-shock-induced death

...ng the body's innate immune response to sepsis and septic shock, according to a study by a research team led...rf2 caused a dramatic increase in mortality due to septic shock in mice. The study's findings, which will be published in the April 2006 issue of the Journal ...

New study aims to stop sepsis in its tracks

...ions can halt the progression to severe sepsis and septic shock. Key to the project is determining whether there are "golden hours" during which prompt, rigorous, standardized care can save patients' lives. The project may establish the first set of standard procedures to diagnose and treat sepsis in emer...

Pharmaceutical compounds found in nation's fresh water

...l Ground Water, pharmaceuticals are being found in septic tanks and, consequentially, ground water due to in...harmaceuticals in areas receiving waste water from septic tanks located in sand and gravel deposits in Missoula, Montana. Many pharmaceutical and pharmaceu...

New approach could lower antibiotic requirements by 50 times

...e in the UK every year. MRSA infection can lead to septic shock and death. ...

8 plants from South Africa may hold potential for treating high blood pressure

...shrub whose seeds have been used in coffee; called septic weed Solanum nodiflorum, also known as white nightshade Tulbaghia violacea, a bulbous plant with hairless leaves often referred to as society or wild garlic Dried leaves from the plants were ground and used to prepare organic and acqueo...

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