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Tag: "sepsis" at biology news

Substance protects resilient staph bacteria

...y fatal but can lead to serious conditions such as sepsis (widespread toxic infection) and endocarditis (inflammation of the lining of the heart and its valves). Because of the ability of PGA to promote resistance to innate immune defenses, learning more about the protein could lead to new treatments for S...

New Estimates For The Causes Of Child Deaths Worldwide

...nia (19%), diarrhoea (18%), malaria (8%), neonatal sepsis or pneumonia (10%), preterm delivery (10%), and as...eonatal period, primarily due to preterm delivery, sepsis or pneumonia, and birth asphyxia should also be addressed. The new estimates of the causes of child ...

Protein prevents detrimental immune effects of bacterial sepsis

...his work is underscored by the fact that bacterial sepsis ranked among the top ten causes of death in both a...1-89). The patients at greatest risk of developing sepsis and SIRS are those with impaired immune systems. When such patients are unable to control the underl...

Community MRSA is re-emergence of 1950s pandemic, study suggests

...taphylococcus aureus bacteria caused skin lesions, sepsis and pneumonia in children and young adults around the world. This pandemic of both hospital and community acquired infections waned throughout the 1960s as the antibiotic meticillin was used to treat these infections. Now researchers have shown that...

HIV accessory protein disables host immunity via receptor-protein intermediary

...cked out and found that their cells were immune to sepsis (pathogens and their toxins in the blood), because the NF-kB molecules did not go into overdrive, kicking up inflammatory molecules called cytokines. This data demonstrate that Vpr attacks PARP-1 activity, so the mice are immune to toxins created by ...

Lack of a key enzyme dramatically increases resistance to sepsis

... could be a potentially useful in the treatment of sepsis and other inflammatory and immune disorders. The...ese individuals are far more susceptible to severe sepsis and have a significantly increased risk of dying from it." Sepsis, the body's inflammatory respons...

Less is more, gene study shows

...people who lack the gene are better able to resist sepsis than those who have a working copy. "This is another indication that loss of the gene would be good for the individual, but it doesn't show that the gene became a pseudogene because of that advantage." However, using population genetics techniques, ...

Mayo Clinic researchers challenge sepsis theory

...has challenged the accepted theory on the cause of sepsis -- a condition in which the body's cells generate ...nce/journal/14714914 . Their findings suggest that sepsis begins with a change in certain cellular receptors that then provoke widespread inflammation, even i...

Researches discover gene critical for protection against septic-shock-induced death

...in regulating the body's innate immune response to sepsis and septic shock, according to a study by a resear...on as potential targets for the next generation of sepsis therapies. The incidence of sepsis in the United States ranges from 400,000 to 750,000 cases per yea...

Stanford snake venom study shows that certain cells may eliminate poison

...oduced by the body during bacterial peritonitis or sepsis (bacterial infection in the blood). In perusing the scientific literature, Metz noticed that endothelin-1 bore a striking similarity to sarafotoxin 6b, the most toxic component in the venom of the burrowing asp, or Israeli mole viper. Knowing also ...

Cell wall of pneumonia bacteria can cause brain and heart damage

...es. S. pneumoniae is a leading cause of pneumonia, sepsis (a potentially life-threatening bloodstream infection) and meningitis (inflammation of the membranes surrounding the brain and spinal cord). The St. Jude team found that pieces of cell wall from S. pneumoniae that escape from the bloodstream enter...

Gene chip technology shows potential for identifying life-threatening blood infection

...for halting its lethal spread, doctors who suspect sepsis typically rush to prescribe powerful antibiotics, ...sts that doctors one day could quickly distinguish sepsis from widespread non-infectious inflammation based on genetic profiles of patients' blood. Testing th...

Researchers identify new weapon to fight deadly bacterial sepsis

...nd the Centers for Disease Control and Prevention, sepsis killed 120,491 hospitalized people in 2000. The same study found cases of sepsis in the U.S. have risen dramatically in recent decades, nearly tripling from 82.7 cases out of every ...

New study aims to stop sepsis in its tracks

...c interventions can halt the progression to severe sepsis and septic shock. Key to the project is determinin...t set of standard procedures to diagnose and treat sepsis in emergency departments. The National Institute of General Medical Sciences (NIGMS), part of the ...

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