Light-sensitive photoswitches could restore sight to those with macular degeneration
...ally making blind nerve cells see, restoring light sensitivity in people with degenerative blindness such as macu...their rods and cones, and have restored some light sensitivity to the remaining retinal cells. Isacoff, Kramer, Flannery and Trauner have now joined forces with ...Results with newer bladeless LASIK equivalent to standard microkeratome LASIK
...ion as measured by reading an eye chart), contrast sensitivity (ability to discriminate bright objects from dark ...eatments compared to density before LASIK. Corneal sensitivity did not differ between microkeratome and bladeless LASIK. Subbasal nerve density and corneal sensiti...With record resolution and sensitivity, tool images how life organizes in a cell membrane
...al in terms of an analytical method with very high sensitivity and high spatial resolution and high chemical information content.'' Boxer's group used atomic force microscopy to locate interesting places and then employed the NanoSIMS 50 to determine what was there chemically. ''Either technique by itself would...New mechanism explains glucose effect on wakefulness
...exin cells." What's more, they wrote, "Because the sensitivity of orexin cell firing to the small changes in extracellular glucose that occur between normal meals has never been tested, the daily physiological relevance of their glucose sensing is also unknown." In their experiments, the researchers engineered ...Elasticity imaging identifies cancers and reduces breast biopsies
...gnant lesions and 105 of 106 benign lesions, for a sensitivity of 100 percent and a specificity of 99 percent. “Our ability to find lesions in the breast has increased significantly over the last 10 years but at the expense of an increased number of biopsies,?Dr. Barr said. “This technique could significantly...Buildup of damaged DNA in cells drives aging
...cs, including the diagnosis of people with unusual sensitivity to sunlight. A German physician had contacted...er medical treatment for his condition. Extreme sensitivity to ultraviolet (UV) radiation from sunlight is a hallmark of diseases caused by defective DNA repair...Pilot study successful in taming allergic reactions to food
...es of egg to see if this will further reduce their sensitivity or even neutralize the allergy altogether. The second study focuses on children who are allergic to peanuts, to see if the desensitization approach can build their tolerance and decrease the severity of their reactions. Peanut allergy, which can b...To elude bats, a moth keeps its hearing in tune
...ellow underwing moth changes its frequency (pitch) sensitivity in response to sound. As a bat gets closer to a mo...and frequency of sound increase. Surprisingly, the sensitivity of the moth’s ear to the bat’s calls also increases, as the moth ear dynamically becomes more sensit...New mechanism underlying pain found
...opathic pain, or the spontaneous pain and abnormal sensitivity following a nerve injury, typically results from a... the inappropriate neuronal activity and resulting sensitivity that follows nerve injury," said Alan Wickenden, Ph.D., Research Fellow in the Pain and Related Diso...Altered perception of reward in human cocaine addiction
...able as $1000, "demonstrating a reduced subjective sensitivity to relative monetary reward," Goldstein said. "Such a 'flattened' sensitivity to gradients in reward may play a role in the inability of drug-addicted individuals to use internal...Protein 'fingerprint' in spinal fluid could spot Alzheimer's disease
...mptoms, we found the new screen to have 93 percent sensitivity to probable cases of Alzheimer's and a 90 percent accuracy in avoiding false diagnoses." Despite their excitement over the new findings, the researchers stress that the results still need to be replicated in much larger populations. "There's a f...Motorola researchers develop selective sensors based on carbon nanotubes
...nize and detect various chemical species with high sensitivity and selectivity while carbon nanotubes are well known for their electronic properties." The peptides are made of 20 or so amino acids, so changing the sequence of amino acids allows the researchers to "tune the peptides and recognize different comp...Faster, more accurate tuberculosis test developed
...d with respiratory discharge--in order to complete sensitivity and susceptibility studies of the MODS test. All s...nder an inverted light microscope for 40 days. The sensitivity of detecting TB was 97.8 percent for MODS culture, 89 percent for automated mycobacterial culture an...Children of allergy sufferers prone to same problem
... not suffer from allergies--7 percent had allergic sensitivity at age 1. The Swedes tested five allergens, two of which were food allergens. The Cincinnati results, however, showed that 28.4 percent of infants born to "atopic" parents, defined as those with allergies, were sensitized to one or more airborne or......ouch on one hind paw but not the other. Each rat's sensitivity was assessed by measuring how much pressure could be applied to a hind paw with a blunt Teflon tip before the rat pulled away the paw. Normal rats could withstand 4.7 times more pressure before withdrawing their paws, compared with rats with sciat...Cocaine high caused by interference in neuronal receiving stations
...lso adjust themselves in complex ways to alter the sensitivity of the receiving neuron to stimulation. Researchers had long known that cocaine affects both dopamine and glutamate receptors on neurons, but the molecular details of those effects were unknown. In their experiments, Wang and colleagues first deter...Origin of inherited pain disorder pinpointed
...nflammatory pain and explain the differential drug sensitivity of PEPD and PE." ...Fruit fly study identifies gene mutation that regulates sensitivity to alcohol
...covered a gene mutation in fruit flies that alters sensitivity to alcohol. The findings, reported in the October ...his behavior. The mutation also altered the flies' sensitivity to cocaine and nicotine as well. Because this gene variant affected the behavioral response to subs...Two nerve cells in direct contact
... toxic effect when strongly stimulated) and tested sensitivity to rotation in the H2 cell. A long series of these... was destroyed, no effect was seen on the rotation sensitivity of the H2 cell. However, if the contralateral HSE cell was removed from the circuit, the rotation se......d principal investigator on the new grant. "As the sensitivity of our measurements improves, so does number of people known to have more subtle cases of HAD. With HIV patients living long enough to re-engage in life and return to work, a condition that often reduces mental function by about 25 percent, and for w...