First direct mechanical communication of mitochondria, cardiomyocyte nucleus shown
...aid. He noted that a "number of studies indicate a sensitivity of nuclei to external mechanical forces and suggest that nuclear deformation could influence gene expression processes. Thus, we hypothesize that drugs or intracellular conditions inducing mitochrondrial swelling could by mechanical means influence g...Tetracycline plus teeth equal gray smile
...oothpaste for two weeks in order to minimize tooth sensitivity from the whitening solutions. Then, the patient co...e and took potassium nitrate, which also decreases sensitivity after bleaching. Then, after the three week time period, the patient uses the trays for another thre...Researchers find molecular 'brake' to cell death
... that decreasing this pool is essential to produce sensitivity in cancer cells to apoptosis," Tang says. Cancers that quickly become resistant to therapy, such as melanoma and ovarian tumors, do so because they have found ways to prevent mitochondria from releasing a lot of CC, he says. Tumor cells also don't w...Traditional Chinese medicine for diabetes has scientific backing
...the muscle and liver that is involved in improving sensitivity of the tissue to insulin ?this in turn helps lower blood sugar levels. In addition, it seems berberine can help reduce body weight". Current medicines for treating type 2 diabetes include metformin and the TZD group of drugs. However, alarge number...Mitochondrial DNA sequencing tool updated
...e MitoChip v2.0 showed in his group's hands better sensitivity that its predecessor to sequence variations in head and neck cancer samples. The v2.0 also detected nearly three dozen variations in the non-coding D-loop, long considered to be a sequencing no-man's land and which the original MitoChip did not incl...Device effective in zapping the pain out of migraines
...a significant reduction in nausea, noise and light sensitivity post treatment. "Perhaps the most significant effect of using the TMS device was on the two-hour symptom assessment, with 84 percent of the episodes in patients using the TMS occurring without noise sensitivity. Work functioning also improved, and ...Sandia work launched on space shuttle shows live cells influence growth of nanostructures
...s added at the cell surface. These may enhance the sensitivity of Raman spectroscopy for monitoring the onset of infection or the course of therapy. The cells also localize proteins at the cellular interface. Assistant Professor Graham Timmins of UNM's College of Pharmacy notes that the encapsulated cells' unu...New study reveals components of cocoa may enhance the appearance of the skin
... tests were conducted to evaluate skin properties: sensitivity to UV irradiation, skin blood flow, skin structure and texture, and skin hydration. The women who regularly consumed the high-flavanol cocoa beverage showed significant improvements in these indicators of skin quality, while those who consumed the f...Survivors of childhood polio do well decades later as they age
...ength and neuronal loss likely is due to increased sensitivity due to their disease experiences, according to Dr. Sorenson. "Patients feel their weakness progressing, but when you measure it, it's very modest," he says. "Likely, they lost so much strength at the time of their illness that any change is very no...Study finds that a woman's chances of having twins can be modified by diet
... its way into the animal's milk. IGF increases the sensitivity of the ovaries to follicle stimulating hormone, thereby increasing ovulation. Some studies also suggest that IGF may help embryos survive in the early stages of development. The concentration of IGF in the blood is about 13 percent lower in vegan wom...Nicotine exposure during development leads to hearing problems
...ceptor and, the UCI study showed, thereby enhances sensitivity to that sound. If that receptor is damaged due to ...e, acetylcholine cannot bind with it and increased sensitivity to the important sound is lost. "While verbal function cannot be measured in an animal, this estab...Polynesia explorers created worldwide web of scientific knowledge
...amisso wrote about Hawaii and other islands with a sensitivity and accuracy still admired among anthropologists." They had plenty of help ?from their captains, officers, voyage artists and physicians, and from Polynesian travelers who came aboard, bringing "their own thirst for knowledge, power, and prestige," ...Pak1 expression increases tamoxifen resistance in breast cancer patients
...r localization contribute to the reduced tamoxifen sensitivity that has been observed in some breast tumor cells. Therapies that target Pak1 expression or activity may therefore represent a strategy to increase the endocrine treatment response in breast cancer." In an accompanying editorial, V. Craig Jordan, ...Compound in dairy products targets diabetes
...rocess fatty acids and also increases the tissues' sensitivity to insulin. "We wondered if CLA was using the same mechanism, in which case it could be used as an anti-diabetes drug," Vanden Heuvel says. To test the idea, he used CLA on mice prone to adult onset (Type-2) diabetes. Results indicated that ...Corals switch skeleton material as seawater changes
... in its physical environment. The aquatic animal's sensitivity to such changes poses questions about its evolutio...d seawaters is further evidence of corals' extreme sensitivity to environmental change," Ries said. "This is particularly significant given recently observed and ...Fertility hope as study shows eggs survive in older ovaries
...me form of infertility. Due to the limitations and sensitivity of human ovaries, few studies have been conducted into the factors that influence egg survival, growth or death in relation to fertility. ...Increased sensitivity to nerve signals keeps diabetes at bay
...ell Metabolism. Therefore, drugs that increase the sensitivity to such signals might offer a new approach to diabetes treatment, the researchers said. Mice in which the pancreas cells that produce insulin, or beta cells, lack so-called M3 muscarinic acetylcholine receptors develop some symptoms of diabetes, inc...Patients to benefit from novel technology revolutionizing high-speed molecular imaging
... diagnostics," he explained. "Due to its very high sensitivity (10 times higher) and definition (up to 2 times th... inherent trade-off between spatial resolution and sensitivity associated with radionuclide imaging," said Patton. "D-SPECT collects photons with much higher effic...Researchers discover how bacteria sense their environments
... change in concentration can be detected, and this sensitivity is maintained over five orders of magnitude in nutrient concentration," said Brian Crane, assistant professor of chemistry and chemical biology and corresponding author of the paper. "Biologically, I know of no other system that is so sensitive over ...Researchers report technique for freezing and preserving genetically enhanced pig embryos
... difficult to freeze and preserve because of their sensitivity to cold due to a high level of lipids in the cells of the embryos. It was expected that it would be even more difficult to freeze and preserve swine embryos that had been produced by in vitro methods. Dr. Prather's team overcame the obstacles to fre...