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Tag: "sensitivity" at biology news

Frog’s ear canal may provide insights for understanding human hearing loss

...derstanding why humans have ear canals: to improve sensitivity to high-frequency sounds." Amolops tormotus, also referred to as the concave-eared torrent frog, is the first non mammalian vertebrate found to be capable of producing and detecting ultrasounds for communication, much like dolphins, bats and some ro...

Carnegie Mellon develops non-invasive technique to detect transplant rejection at cellular level

...e the ability to visualize non-invasively and with sensitivity individual cells and their movement to targeted sites. Our new approach offers almost unlimited potential for monitoring cell therapies, such as those using stem cells, and for tracking cellular and developmental processes," Ho said. For the researc...

A biosensor layered like lasagna

...You can go up to five or six layers to improve the sensitivity of the detector, but after that, the more enzyme layers" inhibit diffusion of the glucose. Now that the glucose enzyme biosensor has passed the test, Lin said, it should be possible to build a similar sensor using other enzymes that react specifica...

Infection 'alarm' yields clues to immune system behavior

... by a drug that curbs inflammation by reducing the sensitivity of IKK. Still other diseases that are characterized by a weak inflammatory response might be helped by a drug that makes IKK even more sensitive to infection messages. The researchers believe their computer model of this cellular alarm system, which...

Rochester scientists develop fast-working biosensor

...r said. The scientists currently are defining the sensitivity levels of the technology, previously called reflective interferometry, and extending the system to other biological targets. ...

New RNAi tools enable systematic studies of gene function

...to several known players, confirming the library's sensitivity as a vehicle for gene discovery. "This critical new tool illustrates the requirement for academic and industry partnerships to drive scientific innovation," said Eric Lander, director of the Broad Institute and a senior author. "The importance of p...

Lack of a key enzyme dramatically increases resistance to sepsis

...r absence of caspase-12 had no effect on apoptotic sensitivity whatsoever. Others authors of the study include Maya Saleh (currently with McGill University), Melissa K. Wolinski, Steve J. Bensinger, Patrick Fitzgerald, Nathalie Droin, Douglas R. Green (La Jolla Institute of Allergy and Immunology and St. Jude ...

Aggression-related gene weakens brain's impulse control circuits

...ala in all men, say the researchers. "Heightened sensitivity in brain circuits important to cognitive inhibition and memory for negative emotional information may contribute to increased vulnerability of men with L exposed to abuse during childhood," suggested Weinberger. "Since only men showed gene effects in...

Behavioral studies show UV contributes to marsupial color vision

...es, a component of marsupial color vision includes sensitivity to ultraviolet wavelengths. In the study, resear... differs from that of primates in that it includes sensitivity to UV wavelengths. In addition to furthering our knowledge of how mammalian color vision functions, ...

Alternatives to the use of nitrate as a fertiliser

...e of nitrate over years favours ?in most plants ?a sensitivity or even toxicity to ammonium. However, the tolerance shown by some crop species such as the pea is of great interest due to the studies of the physiological, metabolic and molecular mechanisms that the ability to tolerate ammonia confers on these pla...

Molecule by molecule, new assay shows real-time gene activity

...tro, rather than in living cells. Finally, the low sensitivity of current techniques for detecting gene expression has restricted analysis to highly expressed genes. Xie's new assay addresses all three limitations. He and his colleagues melded a yellow fluorescent protein called Venus with Tsr, a hydrophobic me...

Cuttlefish masters of disguise despite colorblindness

...agues are currently looking at cuttlefish contrast sensitivity in more detail. "Our result that cuttlefish are able to detect contrast differences of at least 15%, is only an upper limit," says Mäthger. "It's certainly not the contrast threshold, which we would like to know. It seems that cuttlefish camouflage t...

HPV subtype associated with squamous cell skin cancers

... The authors write, "Although sun exposure and sun sensitivity are the major risk factors for [skin] cancers, our data support a role of HPV, particularly beta HPVs, in the development of SCC." ...

New test to detect rare proteins in blood

...ifying antibodies present in a blood sample. The sensitivity of detecting molecules by the new method, called F...oup showed elevated Her2/neu levels. "Clearly the sensitivity of the ELISA assay does not satisfy the current need for the clinical detection of marker proteins t...

Research updates 65-year-old genetic discovery

...an taste bitter substances. For humans, this taste sensitivity may influence nutritional choices and ultimately t...ution. It was only a few years ago, in 2003, that sensitivity to a bitter compound known as phenylthiocarbamide (PTC) was mapped in human genes. "That gene was f...

Can dogs smell cancer?

...d that dogs can detect breast and lung cancer with sensitivity and specificity between 88% and 97%. The high accuracy persisted even after results were adjusted to take into account whether the lung cancer patients were currently smokers. Moreover, the study also confirmed that the trained dogs could even detec...

Protein receptor cools passion of 'kiss and run' nerve cells

...there is a range of protein receptors that vary in sensitivity to the amount of neurotransmitter that's released....smitter can be controlled to take into account the sensitivity and roles played by post-synaptic receptors, new drugs for treating a range of neurological conditio...

Salmonella bacteria use RNA to assess and adjust magnesium levels

..." Groisman says. "We wanted to see if it conferred sensitivity to magnesium levels, which it did." In addition, Groisman's group showed that one RNA configuration was common in low magnesium levels while another was common in high magnesium levels. They also searched the genomes of other bacteria with MgtA g...

Protein found to control tumor growth in certain breast cancers

...s flourished. In addition, there was an increased sensitivity to estrogen-induced cell proliferation and a failu..., further indication that the protein mediates the sensitivity of hormone-dependent breast cancer cells to tumorigenesis. "While still preliminary, our data adds ...

Obese people are more sensitive to pain, suggests study

...ery, a small number of studies have looked at pain sensitivity in obese people, but many of these studies report conflicting results. "Some studies say that obese people are more tolerant of pain, while other studies say they are less tolerant," Emery said. About a third of the study's 62 participants were obe...

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