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Tag: "senescence" at biology news

Tiny roundworm's telomeres help scientists to tease apart different types of aging

... close correlation of telomere length and cellular senescence in mammalian cells, worms with long telomeres were neither long lived, nor did worm populations with short telomeres exhibit a shorter life span. On the other hand, long-lived and short-lived mutant worms could have them either way without any effect...

Getting an evolutionary handle on life after reproduction

...that fish may experience little or no reproductive senescence based on evidence that they continue to produce eggs as adults. It's an open question whether postreproductive lifespan can influence fitness enough to be under selection. But in a field dominated by investigations into the origins of human menopause...

Aging cells, aging body: Fresh evidence for a connection

...ells replicate anywhere from 60 to 90 times before senescence sets in, a phenomenon scientists believe is a safeguard against disease. While senescent cells still function, they don't behave the way young cells do ?and are associated with skin wrinkles, delayed wound healing, weakened immune system response and...

No-mow grass may be coming to your yard soon

...e infertile," Chory explained. "They also regulate senescence or aging. Since brassinosteroids mainly regulate cell expansion, though, they are one of the most important hormones that regulate stature." Knowing the molecular chain of command -- how the hormone acts to influence genetic events that govern deve...

Why don't all moles progress to melanoma?

...s with these cancer-causing mutations is premature senescence ?a form of "suspended animation" that stops the ce...agues found that certain oncogenes use a different senescence mechanism, which doesn't activate the ER, to block the transformation of melanocytes. Both these me...

Turning a cellular sentinel into a cancer killer

...est. What really excited us was evidence that this senescence somehow triggered the innate immune system to kill the tumor cells." Involvement of the innate immune system suggests there may be an unknown mechanism by which cancers can trigger the immune system, he said. Lowe and his colleagues are now exploring...

Short chromosomes put cancer cells in forced rest

...y of telomerase, says further study of the road to senescence should suggest new ways of preventing or treating cancer by interfering safely with telomerase and the cell-suicide system....

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