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Tag: "self" at biology news

Gene thought to assist chemo may help cancer thrive

... in directing chemotherapy-damaged cancer cells to self annihilate, but less attention has been paid to p53’s role in repairing damaged cells,”said John McDonald, chair of Georgia Tech’s School of Biology and chief research scientist at the Ovarian Cancer Institute. When a cell is malfunctioning or inj...

New synthetic self-assembling macromolecules mimic nature

...t when scientists devise new ways for molecules to self assemble into new materials, it is an important achievement. Researchers with the Macromolecules and Interfaces Institute (MII www.mii.vt.edu ) at Virginia Tech report such a development in the online issue for the Journal of the American Chemical ...

Resistance to anti-HIV drugs in Uganda developed due to drug supply problems

... The study followed just under 100 patients who self paid for generic fixed-dose antiretroviral formulations. Findings showed that medications were very effective at suppressing the virus, with full viral suppression in over 80 percent of people on treatment for 6 months. Resistance developed in people...

Engineering the heart piece by piece

... Previously, the group described the results of a self organization strategy, showing that it was possible to engineer heart muscle that closely resembles normal heart muscle physiology without any synthetic scaffolding material. The U-M team and others have also shown how polymeric scaffolds can be used...

Turning a cellular sentinel into a cancer killer

...e in mice, causing blood, bone and liver tumors to self destruct. The p53 protein is called the "guardian of the genome" because it triggers the suicide of cells with damaged DNA. Inactivation of p53 can set the stage for the development of different types of cancer. The researchers' findings show for th...

What does the public really know about HPV?

... insurance coverage, intentions to vaccinate one's self or a daughter were substantially higher when the vaccine was available at little or no cost. For example, 54 percent of parents indicated that they were "very likely" or "somewhat likely" to want the vaccine for their daughter if it were provided at...

Mirrors in the mind: New studies elucidate how the brain reflects onto itself the actions of others

... all observed action (whether perpetrated by one's self or by others) as essentially neutral in ownership. These findings inform our understanding of the motor system's role in social cognition, and support previous suggestions that the motor system may have strongly influenced developments in human socia...

Proteins anchor memories in our brain

...insulin-specific T cells will encounter insulin as self and be filtered out." In the thymus, immature ...d shut down the autoimmune process targeting those self -antigens." The team is collaborating with Jeffrey Bluestone, PhD, director of the UCSF Diabetes C...

Autoimmune disease triggered if T cells miss a single protein early on

...insulin-specific T cells will encounter insulin as self and be filtered out." In the thymus, immature ...d shut down the autoimmune process targeting those self -antigens." The team is collaborating with Jeffrey Bluestone, PhD, director of the UCSF Diabetes C...

Nice guys do finish first in lizards' evolutionary race

... is more than just a blue throat. The mechanism of self identification could be smell, or possibly body language. The lizards have a head-bobbing action that might be signaling genetic simpatico. ...

Lost in thought: Brain research

...is dependent on the mediation of areas involved in self representation ?a vigilant, self-aware "observer" ...l attention, areas of the brain that relate to the self were not only inactive ?they appeared to be vigorously suppressed. The functional brain scans wer...

Researchers find molecular 'brake' to cell death

... a little CC could not mistakenly push the cell to self destruct, Tang says. "When CC is still limited in the cell, perhaps through an accidental release, the nucleotide pool will neutralize the CC so that the cell can stay alive," he says. "So, in a way, it takes a large amount of CC to convince the cell...

Virginia Tech scientists develop process for creating biocompatible fibers

...search group continues to fabricate molecules that self organize and can be electrospun. Potential applications include drug delivery, that is, a carrier and matrix to control the release of drugs." Long's research group is working with Virginia-Maryland Regional College of Medicine researchers at Virgi...

Immune system response to viral DNA is unique

...ntained within all cells. "If this 'tolerance' to self DNA were to break down, cells might mount an antiviral response against their own DNA," he said. "Further characterization of this pathway will shed light on the mechanisms of antiviral responses and how cells discern viral and self-DNA." ...

Skin disease common among Hispanic farmworkers in North Carolina, research shows

...onal susceptibility is used to differentiate one's self from others, usually to show superiority." Arcury said these beliefs need to be challenged in any programs designed to reduce occupational skin disease. "First, the notion that it affects only those who are susceptible needs to be dispelled," he sa...

Rice bioengineers pioneer techniques for knee repair

...t we would be making entire articular end caps via self assembly I would have said you were crazy," said Athanasiou. "The fact that we can do this is an indication of how far the discipline of tissue engineering has progressed." Unlike cartilage, most tissues in our bodies ?including skin, blood vessels ...

Scientists directly view immune cells interacting to avert autoimmunity

...ells of the immune system that pick up and display self proteins that trigger the auto-aggressive T cell response, said Jeffrey Bluestone, PhD, distinguished professor of metabolism and endocrinology at UCSF and senior author on the paper. Bluestone directs the UCSF Diabetes Center. The research provide...

'License to kill' enables powerful immune attack cells in mice

...r outcome--improved ability to distinguish between self and non-self--but this is a very different way of ...elping the natural killer cells to distinguish the self from an invader. But Yokoyama's group found that the inhibitory receptors switch roles during licen...

New insight into autoimmune disease: Bacterial infections promote recognition of self-glycolipids

...tively, these findings suggest that recognition of self by infection is an important mechanism leading to autoreactive T cell activation and, possibly, participates in the pathogenesis of some autoimmune diseases, such as MS and GBS, in which the anti-GSL T cell response may be important," writes Dr. De L...

To translate touch, the brain can quickly rearrange its sense of the body

...et external signals and update its sense of bodily self is more dynamic than had been previously thought and that such updates can happen very quickly, altering within a matter of seconds how body parts and individual touch sensations are perceived. The work is reported by researchers Frederique de Vigne...

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