Man and mouse share genome structures
...lators of development. "In most of the genome, we see short stretches associated with activated histones..." Bernstein said. "However, in the HOX regions, we see huge stretches of genome, many thousands of base pairs in length, that are completely covered by tag...Yellowstone microbes fueled by hydrogen, according to U. of Colorado study
...le,with all the interlacing systems. We can't even see a microbialsystem."Sample extraction was a dangerous and delicate operation. In order toaccurately analyze a hot spring's entire microbial community, Spearneeded to collect only about as much material as a pencil eraser.Sediment samples were scooped ...Columbia research lifts major hurdle to gene therapy for cancer
...lypowerful in eradicating metastases that we can't see and that can't beeliminated by surgery or radiation. Gene therapy, especially forcancer, is really starting to make a comeback."The virus's selectivity for cancer cells is based on two moleculescalled PEA-3 and AP-1 that, the researchers found, are u...Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas
... group had caught up with the others, something we see in human babies too," said Dr. Patti. "They looked and acted the same. There was nothing outwardly different about them." The two groups of offspring ate the same chow diet, maintained a similar weight, and neither group was allowed to become overwei...Neuronal 'traffic jam' marks early Alzheimer's disease
...e early in their life, before plaque formation, to see if we could detect early evidence of abnormal axonal transport," said Goldstein. The researchers used mice that had been engineered to have an abnormal production of human A-beta peptide that produced Alzheimer's-like plaques and subsequent neural de...... is influenced by pharmaceutical ads. We wanted to see what documents were being used to substantiate the claims and how accessible these were to physicians who may want to verify the research findings," said lead author Dr. Richelle Cooper, assistant clinical professor, Division of Emergency Medicine, D...Timing is everything: First step in protein building revealed
...pkins'Institute for Basic Biomedical Sciences. "We see disease largely as anincorrect timing event -- the...next."They had expected -- or at least hoped -- to see a shift in the colorof light once the RNA was mixed in. Instead, they saw two shifts in thecolor giv...Combination therapy boosts effectiveness of telomere-directed cancer cell death
...drug! Perseverance issometimes worth it, as we can see .A new research study published in the January issue of Cancer Cellprovides exciting new information about how to boost the effectivenessof a promising cancer treatment that targets telomeres in an attempt tointerfere with the ability of a cancer cel...GATA: a graphic alignment tool for comparative sequence analysis
...drug! Perseverance issometimes worth it, as we can see .A new research study published in the January issue of Cancer Cellprovides exciting new information about how to boost the effectivenessof a promising cancer treatment that targets telomeres in an attempt tointerfere with the ability of a cancer cel...Research on Worms Yields Clues on Aging
...o look in an unbiased way at availablecompounds to see if any of them happened to have anti-aging activity."The researchers grew the roundworm C. elegans in the presence of the 19drugs and found that an anticonvulsant, ethosuximide, extended theworms' lives from an average of 17 days to an average of 20 ...The transparent organism: EMBLEM and Carl Zeiss give labs a unique look at life
...ch Simon, last month to finalize the details. "We see the SPIM technology as an ideal approach for satisfying the growing demand in highly resolved image information from living organisms. The products based on this technology will form a perfect match with our lines of confocal and multiphoton 3D-imagi...Study finds more than one-third of human genome regulated by RNA
...regulating cellular mechanisms. "It's exciting to see how many genes are regulated by microRNAs. We nowknow that this type of gene control is much more widespread thanpreviously appreciated," says Whitehead Member and MIT professor ofbiology David Bartel.MicroRNAs interrupt a gene's ability to make prot...Live Recombinant Adenovirus Vaccine Technique Explored
... safely provide immunity in one dose. We wanted to see if we could combine the safe and easy-to-use qualities of live adenovirus vaccine with the versatility of recombinant adenovirus virus vaccines that are being developed.?/p> Specifically, Dr. Ketner and his colleagues hope to develop a vaccine fo...NYU researchers simulate molecular biological clock
...regulating cellular mechanisms. "It's exciting to see how many genes are regulated by microRNAs. We nowknow that this type of gene control is much more widespread thanpreviously appreciated," says Whitehead Member and MIT professor ofbiology David Bartel.MicroRNAs interrupt a gene's ability to make prot...Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey
...tly science fiction, says Gilmore.“If bacteria can see cells in the environment, maybe we can tame theseb...and engineer this system so that it can be used to see otherthings in the environment, such as minerals or possibly otherdisease-causing bacteria,?says Gil...Researchers reveal the infectious impact of salmon farms on wild salmon
... in large mixed schools. Thus the scientists could see the effect on the salmon as they moved toward the farm. They found that the juvenile salmon carried almost no sea lice prior to the farm but became heavily infected as they approached it. Unlike other species, pink and chum salmon leave their natal ...Clam embryo study shows pollutant mixture adversely affects nerve cell development
...s, "We cannot say at this time ifthe alteration we see in clam embryos is the same alteration thatcauses ...d company examined periodically recorded images to see whateffect, if any, the chemicals had. They also measured the levels ofproteins in the normal and tr...Study identifies predictors of HIV drug resistance in patients beginning triple therapy
...s, "We cannot say at this time ifthe alteration we see in clam embryos is the same alteration thatcauses ...d company examined periodically recorded images to see whateffect, if any, the chemicals had. They also measured the levels ofproteins in the normal and tr...An HIV Protein Plays a Surprising Role in Gene Activation
...rol. (For more on Tat's role in HIV transcription, see “Novel Enzyme Shows Potential as an Anti-HIV Target?[DOI: 10.1371/journal.pbio.0030074] and “A New Paradigm in Eukaryotic Biology: HIV Tat and the Control of Transcriptional Elongation?[DOI: 10.1371/journal.pbio.0030076].) ...... this research. “It’s fascinating that we can now see that these two rather different individuals were living at the same time and in the same region,?he adds. The researchers also discovered the fossil-rich strata can be linked to sapropels, sediment layers found in the eastern Mediterranean, which, a...