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Tag: "secrete" at biology news

Search on for treatment of slow-healing wounds

... that grab onto a surface, build a colony and then secrete a protective slime that makes them nearly invulnerable to antibiotics and disinfectants. Biofilms can foul drinking water systems, industrial pipelines and cause hard-to-kill infections on medical implants. "Our hypothesis is that once a biofilm s...

Cellular traffic backups implicated in skeletal malformations

...rm the fish's cartilaginous skeleton. Chondrocytes secrete proteins like collagen into the extracellular space, laying down a rigid matrix (the extracellular matrix or ECM) that will form cartilage. Under a microscope, type II collagen can mainly be found in the extracellular space. Only small amounts can...

GlycoFi and Dartmouth report full humanization of yeast glycosylation pathway in Science

...enetic engineering of the yeast Pichia pastoris to secrete human glycoproteins with fully complex, terminally sialyated N-glycans today in the September 8, 2006 issue of the journal Science . To demonstrate the utility of the engineered yeast strains, recombinant erythropoietin (Epo), a protein that stimula...

Who gives stem cells their marching orders?

...nfirm this, showing that aggressive melanoma cells secrete the Nodal protein. Understanding the activity of this gene in embryonic development may hold the key to finding a way to control its activity in tumor cells. "We need to separate the aspects of Nodal function, and how this protein is regulated by the...

Reversing cancer cells to normal cells

...as able to show that the aggressive melanoma cells secrete Nodal, a critical component underling the two-way communication between tumor cells and the embryonic microenvironment. Nodal is an embryonic factor (also called a morphogen) responsible for maintaining the pluripotency of human embryonic stem cells:...

Stem cell therapy shows promise for rescuing deteriorating vision

... cells, neural progenitor cells do many things and secrete many different types of chemicals that may influence the cells around them. "The idea was to test the cells as a continuous delivery system" to shuttle an agent known as glial cell line-derived neurotrophic factor or GDNF, Lund explains. "It's no...

Nanoparticles for delivery of prostate cancer treatment

...es for the Icon, allowing the cells to produce and secrete the Icon. "The key is to have an efficient and safe way to deliver a specific and effective therapeutic agent," said Garen. "Having the nanoparticle targeted specifically to tumor blood vessels, and the Icon derived entirely from human components,...

Scientists discover new, readily available source of stem cells

... bony tissue in mice, and liver cells were able to secrete urea, which the liver produces from ammonia. The potential to generate a broad range of mature cell types is why many scientists believe stem cells have promise to replace damaged cells and tissue in conditions such as spinal cord injuries, diabet...

'Guardian of the genome' protein found to underlie skin tanning

...causes skin cells called keratinocytes to make and secrete a hormone called alpha-MSH, which attaches to nearby skin cells called melanocytes and spurs them to produce skin-darkening pigment called melanin. The chain of events within keratinocytes that leads to alpha-MSH production, however, was a mystery. ...

NIH researchers discover protein that appears to regulate bone mass loss, the cause of osteoporosis

...ection. CD40 ligand appears to regulate cells that secrete chemicals that block bone metabolism, and the loss of this protein in people with X-linked Hyper IgM Syndrome appears to accelerate bone loss. The next step, say the researchers, is to determine whether experimental treatments designed to correct the...

Migration alert -- How tumor cells home in on the lymphatic system

...heir intercellular drainage job, lymphatic tissues secrete small quantities of a signaling molecule. Cells mi...the vessel. Swartz’s group showed that tumor cells secrete this same molecule. Since lymphatics drain fluid, there will always be slow fluid flow going away fr...

Pesticides choke pathway for nature to produce nitrogen for crops

...er legume rotations. __IMAGE_2 Legume plants secrete chemical signals that recruit the friendly bacteria, which work with the plants to convert atmospheric nitrogen into ammonia that, then, is used as fertilizer by the plants. "Agrichemicals are blocking the host plant's phytochemical recruitment si...

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