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Tag: "secrete" at biology news

The making of a fat cell

... sense hormonal and energy status and in response, secrete hormones that maintain whole-body energy balance," said study author Alan Saltiel. "However, you don't want too many, big fat cells. It's a careful balance, and many diseases are associated with either extreme." Lipodystrophies are disorders charact...

System Drastically Cuts Down Botulism Detection Time

... sense hormonal and energy status and in response, secrete hormones that maintain whole-body energy balance," said study author Alan Saltiel. "However, you don't want too many, big fat cells. It's a careful balance, and many diseases are associated with either extreme." Lipodystrophies are disorders charact...

Short-term Bio Sensors Monitor From Afar

... sense hormonal and energy status and in response, secrete hormones that maintain whole-body energy balance," said study author Alan Saltiel. "However, you don't want too many, big fat cells. It's a careful balance, and many diseases are associated with either extreme." Lipodystrophies are disorders charact...

Key To Stem Cell Transplant Success Is Tricking Immune System

... sense hormonal and energy status and in response, secrete hormones that maintain whole-body energy balance," said study author Alan Saltiel. "However, you don't want too many, big fat cells. It's a careful balance, and many diseases are associated with either extreme." Lipodystrophies are disorders charact...

Gene therapy works in mice to prevent blindness that strikes boys

...ding difficulties. In a healthy eye, retinal cells secrete a protein called retinoschisin, or RS1, which acts like glue to connect the layers of the retina. Without it, the layers separate and tiny cysts form, devastating the vision and often leading to blindness in about 1 of every 5,000 boys. UF researche...

Engineered Stem Cells Show Promise For Sneaking Drugs Into The Brain

...ogenitor neural cells were genetically modified to secrete the growth factor when implanted in the striatum, a large cluster of cells in the brain that controls movement, balance and walking. To work effectively, the cells in the striatum require dopamine, a chemical that is produced deep in the brain and t...

Canine cancer vaccine program shows early promise

...erted into these cells, which directs the cells to secrete an immune stimulant. This combination of cells and immune stimulant, when administered as an injection into the patient's skin, has been shown to stimulate the immune system to specifically fight against the melanoma cells. Dogs that first had sur...

Commonly used antidepressants may also affect human immune system

... discovered that these dendritic cells can rapidly secrete serotonin, which activates serotonin receptors on ...ls also have machinery to take up serotonin and to secrete it in an excitatory manner," Ahern said. "The point behind this transmission is not entirely clear, ...

'Nano-keys' bind cell receptors and trigger allergic reactions

...h mast cells. They were chosen because mast cells secrete chemicals and histamines (substances released in allergic reactions that cause runny nose, watery eyes and other characteristic allergy symptoms) and they are the gatekeepers for the allergic immune response. This system can be manipulated experiment...

Scientists discover basic defect in cystic fibrosis airway glands

...used by a loss in the epithelial cell's ability to secrete fluid. This research appears as the "Paper of the.... The second explanation is that the glands still secrete fluid via non-CFTR pathways, but the fluid is reabsorbed by other channels. In fact, it has been pr...

Absence of critical protein linked to infertility

...rus must be transformed into decidual cells, which secrete nutrients that allow the embryo to survive until it plugs into the blood supply. C/EBPb is necessary for decidualization, the researchers discovered. "This protein in the mouse is also in humans," Bagchi said. "We believe it plays a critical role in...

Newly discovered killer cell fights cancer

...s in the invader's outer membrane. Then, NK cells secrete molecules that reach other immune cells, including dendritic cells, known as the main messenger for the immune system. Dendritic cells spread "look here" information about foreign invaders to other immune cells, but do not actually kill the invaders...

Malignant melanoma cells secrete protein required for embryo formation

...roup has discovered that aggressive melanoma cells secrete Nodal, a protein that is critical to proper embryo formation. An article describing this research was published today in the advanced online issue of the journal Nature Medicine. The researchers identified the potent and highly unstable embryonic ...

The molecular mechanism of a diabetes vaccine revealed

... treated with p277 cause the delinquent T cells to secrete anti-inflammatory substances instead of the inflammation-causing ones that they usually make which lead to autoimmune disease. This double action of the peptide weakens the damaging activities of the immune response further. The scientists also showe...

Researchers discover which organs in Antarctic fish produce antifreeze

...tubuloacinar glands that primarily manufacture and secrete digestive enzymes that break down food in the intestine so it can be absorbed. In this case, AFGPs are secreted into the intestinal lumen where they protect the intestinal fluid from being frozen by ice crystals that come in with seawater and food. ...

Tumor wizardry wards off attacks from the immune system

...locked a signaling molecule that pancreatic tumors secrete in abundance, T-reg cells were no longer present in the tumor-draining lymph nodes, suggesting that this signaling molecule, referred to as TGF-beta, has an important role in weaving a tumor's cloak of invisibility. Such information could lead to a m...

Report warns about carbon dioxide threats to marine life

...reatening marine organisms, including corals, that secrete skeletal structures and support oceanic biodiversity. A landmark report released today summarizes the known effects of increased atmospheric carbon dioxide on these organisms, known as marine calcifiers, and recommends future research for determining...

Tarantulas produce silk from their feet

...rom Costa Rica. The team found that the tarantulas secrete silk from spigots on their legs, allowing them to ...n addition to these tarantulas have the ability to secrete silk from their feet, this could represent a major change in our evolutionary hypothesis regarding s...

New finding points way to foiling anthrax's tricks

... samples of anthrax siderophores. Because bacteria secrete siderophores, these molecules can be separated from the bacteria and studied without danger of infection. Using these anthrax bacteria extracts, Abergel and Hoette isolated the two siderophores, bacillibactin and petrobactin, and showed that sider...

Human testis harbors HIV-1 in resident immune cells

...ue architecture as in vivo tissue and continued to secrete testosterone, was able to support infection by HIV-1. Virus produced from the testis culture was fully active as collected virus was able to infect permissive cells in culture. The finding that HIV-1 can replicate within testicular macrophages is...

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