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Tag: "searching" at biology news

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

... The Dana-Farber researchers made the discovery in searching for the function of PGC-1beta co-activator that was isolated in 2002. Experiments including the measurement of gene activity by microarrays showed that saturated and trans fats caused greater activity of the gene that makes PGC-1beta co-activator tha...

Finding Cures For Tropical Diseases: Is Open Source An Answer?

...atabases. Individual pages would host taskssuch as searching for new targets, finding chemicals to attack knowntargets, and posting data from related chemistry and biologyexperiments. Volunteers could use chat rooms and bulletin boards toannounce discoveries and debate future research directions. Over time,the...

Spider Venom Could Yield Eco-Friendly Insecticides

Biochemist Glenn King is searching for an alternative to chemical pesticides. King's research on insect-specific neurotoxins focuses on one the world's most efficient insect predators -- spiders. The Blue Mountains funnel-web spider (Hadronyche versuta) -- a large Australian spider wi...

Development of portable infectious disease detector

...possible applications. Yet, here atthe university, searching for new applications is one of the thingsthat we do best."The origin of the collaboration is an example of the power ofserendipity. It started when David Schaffer, a VIIBRE student whostayed on at the institute as a project engineer after he graduate...

Agilent Technologies releases automated literature search tool for biology researchers

...new plug-in to avoid the daunting task of manually searching for each gene and protein in the scientific literature and patents. "Mining past literature for information about proteins and protein interactions is a critical step for building models of cells," said Trey Ideker, assistant professor at the Univer...

International HapMap consortium expands mapping effort

.... This approach can reduce the work and expense of searching the genome for hereditary factors in common disease by a factor of 20 to 40 compared with current, brute force approaches. "This new partnership underscores the private sector's enthusiasm for the HapMap and its potential as a tool for the understan...

To control germs, scientists deploy tiny agents provocateurs

...m sensing are beneficial, so we are simultaneously searching for compounds that selectively turn on group behaviors." Using new combinatorial chemistry techniques, Blackwell and her team are screening through hundreds of molecules at a time. The researchers have so far unveiled three promising organic compoun...

Elephant seal pups suffer from ocean warming

...ale seals have to swim further and spend more time searching for food. As a result, they gain less body mass while pregnant and have fewer reserves to draw on during nursing. Nursing pups get all nourishment from their mothers; changes in ocean temperature therefore directly affect the weight, and the survival...

Tendency to hair loss inherited from the mother

... identify more genes involved the research team is searching for more volunteers. "Men under 40 with severe hair loss can take part," Dr. Kruse says. "If they have a brother who is affected and the parents are also prepared to give blood samples, so much the better. Volunteers taking part in the study will, of...

Designing vaccines by computer

...mber of compounds drug companies need to test when searching for new vaccines. Researchers funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and working at the Edward Jenner Institute for Vaccine Research are using a very simple concept to help speed up the development of vaccines. ...

Stealth Worms May Improve Insect Pest Control

...m the tops of the trees all the way to the ground, searching for nematodes that are potential insect pathogens. The misconception is that they are concentrated more in temperate zones, but this is not true. We're trying to unveil the mystery of nematode diversity in the tropic regions." In Jordan, she and her...

Bobbing birds do it for a reason

... observation, however, was that when the birds are searching for food, they walk at a moderate pace that allows the head to be held still more than 50% of the time. In other words, when foraging, whooping cranes favor visual fixation. This result strongly suggests that visual fixation not only removes motion ...

Gov't Creates Gene Database of Normal Human Tissues

...se for normal tissue from human organs. Scientists searching for genes that go awry and cause disease can use the NCI database as a crucial point of reference because it pinpoints which genes are expressed in many of the body's major organs under normal conditions, without known disease. Scientists can compar...

Scientists analyze chromosomes 2 and 4

...s that have disappeared over the course of time by searching other mammals' DNA for similar patterns of duplication," said Richard K. Wilson, Ph.D., director of the Washington University School of Medicine's Genome Sequencing Center and senior author of the study. In another intriguing finding, the researcher...

Natural Killers Could Lead to New Hepatitis Treatments

...k this is a reflection of their normal function of searching for antigen,?said Littman. “Whenever there is detection of antigen reflecting some kind of damage or local infection, the cell would stop in the vicinity of that signal and provide cytokine signals that would attract other inflammatory cells that des...

Research on antibiotics receives historical recognition

...til late 1930s that he turned his attention to the searching for microbes that attacked other microbes. Waksman received the Nobel Prize for physiology or medicine in 1952 for "ingenious, systematic and successful studies of the soil microbes" that led to the discovery of streptomycin. He died in 1973. ...

Bacterial genome sheds light on synthesizing cancer-fighting compounds

...uced the sought-after patellamides, until now. By searching for patellamide synthesis instructions in genomic sequences, scientists found the bacterium indeed has the necessary genes to produce these potentially important biochemicals, solving the source mystery. Knowing which genes Prochloron used for patell...

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

...A molecule like fingers sliding down a guitar neck searching for the right chord, examining each base pair as it goes. Each time it finds the sequence GATC it stops and methylates the A nucleotide. Dam must move quickly, because if the bacteria reproduce with the wrong methylation pattern, gene expression will...

ORNL, UC Berkeley unravel real-world clues to Earth's mysteries

...esponsible for the informatics related to database searching and data dissemination. The team detected 2,036 proteins from the five most abundant species in the bio-film, including 48 percent of the predicted proteins from the most abundant bio-film organism, Leptosprillum group II. Researchers noted that thi...

Drawing with DNA: 'Bioart' illuminates genomics

...me bioinformatics comparison: BLAST begins to run, searching through the rice data for a homologue ?conducting in a novel (and visible) way the same sequence analysis done by scientists. Results are presented as two superimposed pictograms. "This high-dimensional visualization reduces the complexity of sequen...

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