New study reports hotel guests at risk from carbon monoxide poisoning
...he LDS Hospital Hyperbaric Medicine Department and searches of legal databases and online news databanks, the researchers found 68 incidents of CO poisoning occurring at hotels, motels, and resorts between 1989 and 2004. In these incidents, 711 guests, 41 employees or owners and 20 rescue personnel were accid...Scientists uncover new target in cancer mutation puzzle
...d for a long time that the way to develop rational searches for new drug targets is to first understand how these oncogenes cooperate. And in this study we've shown for the first time that this idea might work." Land was among the scientists in the mid-1980s who first discovered oncogene collaboration. Sin...Gene screen for breast cancer better than pathologist's 'eye'
...en the most powerful microscopes. Sukumar's test searches for unusually high amounts of chemical tags embedded by a process called methylation within critical regions of DNA. The tags attach to the "on" switch of genes which starts the message-manufacturing process. Cancer cells have abnormal levels of me...Cracking the genetic code for control of gene expression
...ftware called EEL (enhancer element locator) which searches genomic sequence for regions where many transcription factors bind DNA side by side. Finding the same region with high frequency of transcription factors in several species indicates that the DNA element regulates gene expression. The researchers sho...Powerful new tool for studying brain development
...St. Jude of bioinformatics software that routinely searches scientific databases for new information on genes linked to brain development, said Perdeep Mehta, Ph.D., the group leader in bioinformatics at St. Jude's Hartwell Center for Bioinformatics and Biotechnology. Bioinformatics is the use of computers, s...Novel enzyme offers new look at gene regulation
...the proteins share little else in common. Database searches predict more than 100 total proteins found in organisms as diverse as bacteria and man contain the JmjC domain. This suggests that many other proteins may act similarly to methyl groups from histones or other proteins. The implications of the new fi...Team Invents Device For Weighing Individual Molecules
...on their weight. Today, high-throughput proteomics searches are often done at facilities possessing arrays of conventional mass spectrometers that fill an entire laboratory and can cost upwards of a million dollars each, Roukes adds. By contrast, future nanodevice-based systems should cost a small fraction of...Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression
...ing sequences. But this didn't work. The homology searches yielded far fewer targets than expected and could not account for all known microRNAs. The reason, says Han, is that scientists were trying to predict the microRNA targets using the sequence homology of the full-length microRNAs. In their Cell artic...Agilent Technologies releases automated literature search tool for biology researchers
... The Agilent Literature Search tool automatically searches for and extracts information from multiple textual...pes of relationships being looked for. The plug-in searches accessible databases and generates a computational representation of gene/protein associations group......mbled with whole genome shortgun approach. Through searches of 19079 full length cDNA, 97.7% of complete genes were found in the two genomes. After adjusting for residual errors of predictions with EST data, the number of genes is estimated to be between 30,000 to 40,000. Among them, only 2-3% genes are uniqu...