'Computer-chemistry' yields new insight into a puzzle of cell division
..., and pretty tedious." After this trial-and-error search remained fruitless, Rudolph, his graduate students...d programmer Paul Brown, then began narrowing that search further. They did so by using a different software program that could identify the highest and lowes...New methods offer insight into regulatory DNA
... varies among genes. New tools are needed in the search of our genome for the sequences that contribute to disease, tools that will harness the massive amounts of DNA information and transform them into information of real biomedical utility. The methods described here, with the power of the HapMap data a...Worms know bad food when they smell it
...the worm to live for several days ?and head off in search of better food. So, the researchers surmised, knowing whether or not certain bacteria are toxic is something "worth learning" for the worm. To find out whether worms learn from experience to avoid or seek out certain types of bacteria, the researc...UCLA discovery will aid in treatment of patients with a deadly brain cancer
...malignant brain tumors are not curable, making the search for better treatments even more urgent, Mischel said. A protein called epidermal growth factor receptor (EGFR) is commonly amplified in glioblastoma, making it a prime focus for therapies. Drugs such as Tarceva and Iressa target EGFR, blocking the c...Scientists sequence DNA of woolly mammoth
...ears will be an open book to the researchers. The search is now on for more specimens from plant, animal, and man that can illuminate the route evolution took on its way from the past to the present, and that can perhaps clarify the role environmental changes did play in the extinction of an entire species......roke. Two factors make the study promising in the search for treatments for this deadly disease. First, shutting down the IKK2 signal had beneficial effects even when it was done a few hours after the stroke. That is important when thinking about possible human therapies; it usually takes time for a patien...Mining biotech's data mother lode
...entify protein interactions they then need to do a search on their company intranet to see what other work c... the topic. Finally, the researcher must perform a search of academic journals to find relevant journal papers. Currently PubMed, the most important public li...Novel protein complex enables survival in hostile environment
...naschii has a sulfite-reducing enzyme and began to search for this system. Protein analysis of M. jannasch...niques, they identified the gene for the enzyme. A search showed that this gene exists only in hydrothermal vent methanogens and their close relatives, but no...Scientists pinpoint inflammation gene
...rough medications that regulate SEPS1. An expected search for other genes that influence SEPS1 also could lead to other potential areas for drug intervention. Researchers studying diseases impacted by inflammation also might look to see what role SEPS1 plays in disease susceptibility. Already, ChemGenex a...The shape of things to come: Morphology database going global
... system more user friendly and offer more advanced search techniques, according to project manager David Gai...lso will be able to add comments to the images and search comments made by other scientists - a quick and efficient way to communicate research results. "We'...Researchers know what you were about to say; fMRI used to detect memory storage and retrieval
... memory surfaces. "This study shows that, as you search for memories of a particular event, your brain state progressively comes to resemble the state it was in when you initially experienced the event," said Sean Polyn, a post-doctoral fellow at the Computational Memory Lab in Penn's Department of Psycho...A little telomerase isn't enough
...he telomerase gene, says Greider. "If you were to search for the genetic mutation behind this mouse's disease, you wouldn't find it -- there isn't one," says Greider. "These mice develop disease only because their telomeres are short, and having telomerase doesn't lengthen them right away." The condition ...Sudden change in social status triggers genetic response in male fish, study finds
...indless creatures that instinctively swim about in search of food and mates. "Our study shows that the male cichlid is obviously interacting with the world around it," says Burmeister, a former postdoctoral fellow in the Fernald lab, now assistant professor of biology at the University of North Carolina-Cha...Amphetamines reverse Parkinson's disease symptoms in mice
...ndently of dopamine opens up new directions in the search for prospective anti-Parkinsonian drugs, the researchers said. The researchers, led by James B. Duke professor of cell biology Marc Caron, Ph.D. and Assistant Research Professor Raul Gainetdinov, M.D., Ph.D., of Duke, made the discovery after testin...Scientists closer to new cancer detection method
... proteins. The technique could enable doctors to search within extremely complex fluid or tissue samples to pinpoint biomarkers - proteins that signal that something is amiss. "Even when the cancer biomarkers are in extremely low concentration we have been able to detect them," said Weihong Tan, Ph.D., a...Biologist Discovers What May Be World’s ‘Pickiest?Mates
...nimals sample just a few mates, presumably because search costs override the benefits of lengthy searches,?she said in her paper. But female California fiddler crabs are much pickier, she discovered in her study, checking out male suitors and their bachelor pads an average of 23 times before making a final ...Color perception is not in the eye of the beholder: It's in the brain
...sity of color cones, but Williams is continuing to search for the responsible combination of genes. ...U-M scientists discover identifying markers for primitive blood-forming stem cells
...d of stem cell science. Currently, scientists must search for many different markers and use complex procedures to separate rare hematopoietic stem cells, or HSCs, from other cells in a blood sample. Using SLAM markers will streamline the process considerably, says Mark J. Kiel, a student in the U-M Medical...Molecular Partners Required For Appropriate Neuronal Gene Repression
...to counteract this process in animal models in our search for human treatments." Other key OHSU researchers involved in the study are: Stephen Back, M.D., Ph.D., an associate professor of pediatrics and neurology in the OHSU School of Medicine; and Bruce Bebo Jr., Ph.D., a scientist in the OHSU Neurologica...OHSU researchers discover potential mechanism to repair brain damage linked to Multiple Sclerosis
...to counteract this process in animal models in our search for human treatments." Other key OHSU researchers involved in the study are: Stephen Back, M.D., Ph.D., an associate professor of pediatrics and neurology in the OHSU School of Medicine; and Bruce Bebo Jr., Ph.D., a scientist in the OHSU Neurologica...