screening 2 6

Tag: "screening" at biology news

Greasing interferon's gears may pave way to greater therapeutic benefits, fewer side effects

...cording to Holtzman. The researchers are currently screening newborn infants for levels of Stat1 action and tracking their susceptibility to viral infection. In addition, the group is studying transgenic mice engineered to carry the same Stat1 mutations that were examined in cells. In this way, the researche...

Yale participates in global human genome initiative

...on is expected to help optimize rapid, genome-wide screening and accelerate drug discovery. The other Global Initiative founding member institutions are the Campbell Family Institute for Breast Cancer Research at Princess Margaret Hospital and the Samuel Lunenfeld Research Institute at Mount Sinai Hospital i...

Researchers identify molecular anchor that allows bacterial invasion of central nervous system

...er. Through a process that involved generating and screening thousands of Streptococcus mutants in a laboratory model of the human blood-brain barrier, the researchers found that a gene called iagA (short for invasion association gene-A) played a central role. By producing a fat-sugar complex that anchors LTA...

Chernobyl: The true scale of the accident

...gency personnel. The Report also calls for focused screening of children exposed to radioiodine for thyroid can...workers for non-thyroid cancers. However, existing screening programs should be evaluated for cost-effectiveness, since the incidence of spontaneous thyroid canc...

UT Southwestern researchers develop screening test for cells that activate immune system

... are the first to create a large-scale, cell-based screening method that identifies which compounds activate im...mise for future cancer-fighting vaccines. The new screening technique can scan thousands and even millions of compounds to identify those that activate dendriti...

Study provides insight into cellular defenses against genetic mutation

... destruction of the rest. They also found that the screening process, called nonsense-mediated mRNA decay (NMD)...dical therapies," Maquat said. "Beyond its role in screening out faulty mRNAs through immediate decay, we have also learned that the NMD factor Upf1 is part of a...

Prescription pain patch abuse blamed for increase in deaths

...cating prescribing physicians on the importance of screening and monitoring their patients for addictive disorders in order to help decrease the abuse of the patch." ...

Most embryos produced during IVF do not result in live births

...ify the best embryos. "Some potential methods for screening embryos include using pre-implantation genetic diagnosis and biochemical markers of embryo viability," said Patrizio. "In addition this study should also move the field toward perfecting methods of egg production." ...

New results validating Pall prion reduction filter disclosed at ISBT Congress

...ivity and specificity. The implementation of donor screening would be problematic without the availability of confirmatory assays to inform discussions with potentially infected donors. Prion Reduction Confirmed Sam Coker, Ph.D., Principal Scientist of Pall Corporation, released new research results that fur...

Rutgers to lead $52.7 million protein research program

...several potential antibiotic drug targets and drug screening assays for which we have submitted patents," Montelione said. "However, there are many protein families that still do not have known structural representatives." NIGMS has now funded four of the strongest pilot program centers, including NESG, as Ce...

Drugs from the deep blue

...ng highly sensitive instrumentation, sophisticated screening capabilities and discoveries from mapping the huma... biologically active molecules and high-throughput screening techniques. Most of Molinski's samples come from sponges and tunicates, marine creatures that can n...

Genetic variation alters response to common anti-clotting drug

...ieder said there's a high probability that genetic screening for the VKORC1 gene could result in better warfarin dosing, they agreed that more studies need to be done first. "What we've done is the basic science," said Rettie. "This complete genetic analysis of VKORC1 provides the mechanistic framework and im...

Forsyth scientists find three bacteria associated with oral cancer

...ors or dentists within several days. The need for screening Government statistics show that, every year, some 30 thousand US residents are diagnosed with oral cancer. Of those diagnosed, more than 90 per cent are found to have OSCC. If discovered and treated early, OSCC has a five-year survival rate of 80-to-...

NYU chemists use computer simulation to enhance understanding of DNA transcription

...ke structure. However, under high-salt conditions, screening of linker DNA repulsion allows close contacts and attraction between nucleosomes, allowing the array to fold. As chromatin folding or unfolding prevents or allows the transcriptional machinery's access to the DNA in a chromosome, this computer simula...

Results of world's first gene therapy trial for arthritis show approach safe, feasible

..., reintroduced several weeks later after intensive screening and determination of gene expression. "Given that... seven weeks later, following extensive laboratory screening of the genetically modified cells, patients returned to the clinic, where the cells were injected in...

U-M researchers identify new blood test for prostate cancer

...2 biomarkers that together provide a more accurate screening for prostate cancer than the current prostate spec... diagnosed with prostate cancer this year. Current screening methods involve a blood test to check for prostate specific antigen, an enzyme produced by the prost...

Why do aneurysms form? New studies suggest leading role for white blood cells

...k patients," says Upchurch. "In addition to better screening and adequate monitoring of known AAAs, this kind of treatment is badly needed." Upchurch and his colleagues performed the research in the Conrad Jobst Vascular Research Laboratories, part of the Section of Vascular Surgery in the U-M Medical School....

Hopkins scientists uncover 'tags' that force proteins to cell surface

...he protein to the cell surface, you can't use this screening technique. If we can force proteins to the cell surface, we can overcome obstacles that have prevented laboratory study of some really important proteins," says Li. The application of these surface tags to force protein transportation to the cell sur...

MicroRNA tweaks protein that controls early heart development

...." The UT Southwestern research team is currently screening human patients with congenital heart disease for mutations in the gene miR-1 to determine what health effects such a mutation might cause. They also are studying mice and fruit flies lacking miR-1. Dr. Srivastava said the field of microRNA studies h...

Engineered molecule amplifies body's immune response

...treating viral infection and cancer. They are also screening for drugs that might increase Stat1 responsiveness. These experiments may eventually lead to many improvements in cancer therapy as well as the treatment of other infections. Basically, any situation in which interferon hyper-responsiveness might be...

1 2 3 4 5 6 7 8