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Tag: "screen" at biology news

Mammalian Transcriptome Mapped

...artis Research Foundation have discovered a way to screen through hundreds of RNA molecules for their functions within cells. For details on these results, see the Scripps Research news release at http://www.scripps.edu/news/press/090105a.html Antisense Transcription--What Is It? Another major finding of ...

Past illegal blood donation in China linked to hepatitis C virus infection

...ing the 1980s and early 1990s, and that failure to screen for HCV in transfusion recipients increased their risk of infection as well, according to an article in the November 15 issue of The Journal of Infectious Diseases, now available online. Some blood donation facilities in rural China illegally pooled...

Housecat-sized Siberian tiger cubs get collared

... Morrow. "With this knowledge in hand, we hope to screen our patients and identify the genomic mechanism underlying this important disease," says Morrow. Contact: Bernice Morrow, Ph.D. Professor, Albert Einstein College of Medicine Phone: 718-430-4274 E-mail: morrow@aecom.yu.edu Looking for genes ...

Studies on human genome variation provide insight into disease

... Morrow. "With this knowledge in hand, we hope to screen our patients and identify the genomic mechanism underlying this important disease," says Morrow. Contact: Bernice Morrow, Ph.D. Professor, Albert Einstein College of Medicine Phone: 718-430-4274 E-mail: morrow@aecom.yu.edu Looking for genes ...

Complex gene interactions account for autism risk

...e." Such findings may ultimately yield a method to screen for individuals at high risk for the disease, she added. "The new findings offer important new information for families affected by autism about the complexity of the disease," said clinical psychologist Michael Cuccaro, Ph.D., a study co-author als...

UT Southwestern researchers discover master switch in cell death

...f there’s a problem with Mule, or perhaps we could screen beforehand,?Dr. Wang said. Other UT Southwestern researchers involved in the study were Wenhua Gao, student research assistant, and Dr. Fenghe Du, research specialist. The work was supported by the Howard Hughes Medical Institute, the National Inst...

Drugs from the deep blue

...realized that they could apply the same methods to screen 124 sponges that Molinski's group had recently collected off the coast of Western Australia. In one of the samples they came up with xestospongin C, the first of a class of drugs now widely used in research studies on calcium transport. Xestospongin...

UCLA scientists reveal how Nipah virus infects cells

...h virus enters to infect these cells. "We now can screen for small molecules that will block viral entry via Ephrin B-2 and develop them as therapeutic drugs," said Lee. "Because pigs are particularly susceptible to Nipah infection, public health officials could use these drugs to protect the animals, pig ...

Virus uses tiny RNA to evade the immune system

...their study, Grundhoff wrote a computer program to screen the SV40 genome for possible microRNA precursors. MicroRNAs are made from messenger RNA molecules with distinctive hairpin folds. The hairpin structure is diced into a microRNA segment that works with another complex to disable other messenger RNAs w...

UCLA researchers identify key enzyme linked to childhood blindness

...searcher in ophthalmology, performed an expression screen in cultured human cells, looking for a gene that caused these cells to convert vitamin A into 11 cis retinol. The researchers are now studying the effects on retinoid isomerase activity of specific disease causing mutations in the RPE65 gene, which ...

'Underground' tunnels discovered as means for communication between immune system cells

... the cell, he had already given it a jab. "On the screen it looked like flash bulbs going off in a dark concert arena," Dr. Salter recalled of that moment, when to both their great surprise the researchers witnessed how that little mishap had caused the macrophages to release bursts of calcium. Returning ...

Hunt for human genes involved in cell division under way

...ising." The systematic search and analysis of the screen is set to be completed by the end of 2005. ...

The synapse is a shotgun

...ejnowski. "There's just nothing solid on our radar screen right now," he said. "There is speculation that ectopic release represents some sort of spillover that neurons use under certain circumstances. Or, it may be an alternative mode of neurotransmission that neurons use at different points in their life ...

'Shifty-eyed' Monkeys Offer Window Into Brain's Social Reflexes

...st subjects' attention to the center of a computer screen by showing them a yellow square. The subjects woul...ce would disappear and to the left or right on the screen a yellow square would flash. The researchers used a magnetic coil technique to measure with high ac...

A novel method to measure circadian cycles

... to rely on prolonged behavioural observation. To screen for and identify circadian rhythm variations in hu...n the future, scientists may use the new method to screen large populations for genetically linked sleep disturbances such as advanced and delayed sleep phase...

Mass production of human papillomavirus could lead to gains against cervical cancer

...that the production technique could offer a way to screen for HPV antiviral drugs and could lead to enhanced vaccines that consist of live attenuated virus. "Current vaccines in clinical trials consist of capsid proteins and trigger an immune response to those proteins," he said. "However, in its earliest s...

Engineered molecule amplifies body's immune response

...file. In terms of diagnosis, it may be possible to screen patients for the level of Stat1 responsiveness to interferon, and if found to be low, that would make them candidates for a strategy to improve Stat1 responsiveness using our methods." ...

Scripps research scientists identify infertility molecule

... "This is a receptor that wasn't on anyone's radar screen from a fertility standpoint," says Jerold Chun, M.D., Ph.D., who conducted the study with his research associate Xiaoqin Ye, M.D., Ph.D., and their colleagues at The University of Tokyo, Washington State University, and the Fred Hutchinson Cancer Res...

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

...eening techniques and high throughput equipment to screen for potential inhibitor compounds against the Dam enzyme. ...

Scientists identify genes responsible for 'black rot' disease in vegetables

...ts the largest comparative and functional genomics screen for a plant or animal bacterial pathogen to date, is published online today in the journal Genome Research. "Black rot" is caused by the pathogenic bacterium Xanthomonas campestris pathovar campestris (or Xcc). Under favorable conditions (high humid...

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