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Tag: "screen" at biology news

New biochip helps study living cells, may speed drug development

...ology does not kill the cells, it could be used to screen and identify different crop lines, Porterfield sai...m a group of maize cells with these genes and then screen each cell to determine the most efficient. Then you could raise the one that needed the least fertil...

Contrary to common wisdom, scientist discovers some mammals can smell objects under water

...cent accuracy. When the grid was replaced with a screen with openings too small for the air bubbles to pass through, however, the moles' performance dropped down to the level of chance ?the same as their performance with no-scent trails. In order to see if this capability was limited to the star-nosed m...

Female pronghorns choose mate based on substance as well as show

...hoose a mate, she can't order a laboratory genetic screen for each suitor. Instead, she has to rely on external cues that may indicate genetic quality. Until now, biologists have focused on elaborate ornaments, such as the peacock's tail, as cues that females might use. The thorny problem has been to expla...

Scientists work to identify genes that contribute to early heart attack risk

...ence. Using the latest technology, scientists will screen tissue samples from the study looking for genetic variants that may predispose individuals to develop early atherosclerosis. "Perhaps the most remarkable thing about this study is the large number of genetic variants that we’re going to study," sa...

Genetic 'roadmap' charts links between drugs and human disease

...s identified gedunin in a high-throughput chemical screen for molecules that disrupt hormone signals in prostate cancer cells and then used the Connectivity Map to help uncover its precise molecular action. As confirmed through additional work, gedunin disrupts a key quality control mechanism in the cell. ...

Test reveals effectiveness of potential Huntington's disease drugs

... using cultured cells provides an effective way to screen drugs against Huntington's disease and shows that two compounds ?memantine and riluzole ?are most effective at keeping cells alive under conditions that mimic the disorder, UT Southwestern Medical Center researchers report. "These drugs have been ...

Study identifies substances in grapefruit juice that interact dangerously with some drugs

... grapefruit. In addition, it should be possible to screen new foods for the potential for drug interactions by determining whether they contain furanocoumarins. "Finally, it may be possible to add furanocoumarins to formulations of certain drugs that tend to be poorly or erratically absorbed to improve th...

Biofuels researcher searches for new sources

...g Department of North Carolina State University to screen chemicals and enzymes that pretreat and convert biomass into sugars. "Biomass energy can contribute to cleaner air through reduction in greenhouse gas emissions. It can alsoimprove rural economies, and reduce energy dependence on foreign petroleum ...

UCSD researchers develop 'smart petri dish'

...a "Smart Petri Dish" that could be used to rapidly screen new drugs for toxic interactions or identify cells... drug has on the liver. But it's very expensive to screen every potential candidate on living animals, typically rats. So if you can use just a few cells fro...

Scientists solve sour taste proteins

...d. Matsunami said he plans to use this finding to screen for chemicals that can block the function of these sour taste cells.The research also could lead to a better understanding of how the sense of taste functions neurologically, he said."We still do not know what is happening in the brain -- that is, ex...

Coming soon: 3-D imaging that flies 'through' and 'around' cancer

...s an image of the inside of the colon onto a video screen so its lining can be examined. While the initial findings are exciting, the researchers proved the concept rather than validated the technique. Future validation studies will be conducted and software tools need additional development, said Quon, w...

Gene screen for breast cancer better than pathologist's 'eye'

...entists have found that a method they developed to screen body fluids for certain kinds of cells and some of...fluid," says Sukumar, who believes that their gene screen may miss cancers if they overlook any hidden breast ducts. Improvements in getting an accurate rep...

Himalayan forests disappearing

...anipulate joysticks to move a cursor on a computer screen from a starting point to a goal. Importantly, the researchers required the monkeys to maneuver the cursor within a maze to reach the goal and to perform those maneuvers in a discrete stepwise fashion with pauses in between. This stepwise approach ena...

The brain's executive is an 'event planner'

...anipulate joysticks to move a cursor on a computer screen from a starting point to a goal. Importantly, the researchers required the monkeys to maneuver the cursor within a maze to reach the goal and to perform those maneuvers in a discrete stepwise fashion with pauses in between. This stepwise approach ena...

New strategy rapidly identifies cancer targets

...ea. "Now we know to add JAK3 to the mutations we screen for in our leukemia patients and should look to see if JAK3 mutations are present in other cancers," he said. ...

'Signature' of chromosome instability predicts cancer outcomes

...nterest to researchers -- by making it possible to screen a large number of drugs for efficacy, Szallasi notes. With further development, the team's work could also form the basis of a diagnostic tool that could be used in the clinic. The human genome is at constant risk for mutations due to environmental...

Magnetism and mimicry of nature hold hope for better medicine, environmental safety

... give the pharmaceutical industry improved ways to screen for new drugs by being able to run several types of tests simultaneously on an extremely small scale. The next step in developing this technology is under way in Hayes' laboratory and through the team's collaboration with Joseph Wang, a professor i...

Parkinson's disease mechanism discovered

...ndquist and her colleagues had conducted a genetic screen in yeast to discover genes whose activity affected.... However, importantly, the results of our genetic screen have given us a way to ask important questions about these other aspects of alpha-synuclein toxicity...

Purdue creates new low-cost system to detect bacteria

...the pattern of scattered light is projected onto a screen behind the petri dish. This "light-scatter pattern" is recorded with a digital camera and analyzed with sophisticated software to identify the types of bacteria growing in colonies. "There are potentially thousands of applications for this new tech...

New human retrovirus originated in mice

...ave presented evidence contesting that theory. To screen for viruses in the prostate tissue samples, DeRisi...their evolution from related viruses. The initial screen of the RNASEL-mutant prostate cancers revealed the presence of a genetic sequence that closely resem...

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