Clue found to Epstein-Barr virus' ability to form and sustain tumors
...ein, it will be easier for us to develop assays to screen for small molecules that will compete with the protein in binding to EBNA-1," Sugden says. "By preventing the cellular protein from binding with the segment, EBNA-1 will not be able to carry out its function and the tumor cells it sustains will die."...'GreeneChip' -- New diagnostic tool that rapidly and accurately identifies multiple pathogens
... for single pathogens, methods that simultaneously screen for multiple agents are important, particularly when early accurate diagnosis can alter treatment or assist in containment of an outbreak," stated W. Ian Lipkin, MD, director of the Greene Infectious Disease Laboratory at the Mailman School’s Departm...New technology to speed up research into Huntington's disease
..., using an automated touch screen. It is hoped the screen will also allow researchers to study more effectiv...isease on their motor abilities. The automated screen developed by Cambridge scientists provides a simple means of assessing cognition, in a way that requ...Stroke symptoms common among general population
...he JAMA/Archives journals. Using brain imaging to screen individuals without a history of stroke reveals that many have had an undiagnosed or silent stroke, according to background information in the article. One previous study found that 11 percent of individuals age 55 to 64, 22 percent of those ages 65...Transmission of antibiotic-resistant bacteria linked to previous intensive care unit room occupants
...carried MRSA and 658 carried VRE, leaving 7,629 to screen for the acquisition of MRSA and 7,806 for acquisition of VRE. The average patient age was 61 years, and 58 percent were male. Fourteen percent of these ICU patients stayed in rooms in which the prior occupant had MRSA and 13 percent stayed in rooms...Carnegie Mellon scientists use 'green' approach to transform plastics manufacturing
...s for nanoscale carbon structures used in computer screen field emission displays and semi-conductors that regulate the flow of electricity in sensors, some only a fraction of the width of a hair. ATRP differs significantly from conventional polymer manufacturing methods. This "living," synthetic process ...Scientists design simple dipstick test for cocaine, other drugs
...irst responders or emergency room staff to quickly screen individuals for a variety of drugs and other chemicals." Lu said. Aptamers are single-stranded nucleic acids that can bind to specific molecules in three-dimensions. For each molecular target, such as cocaine, a corresponding aptamer can be selecte...Key to lung cancer chemo resistance revealed
... findings with a larger set of samples and then to screen for appropriate drugs. Funding for the study was provided by the National Cancer Institute Lung SPORE (Specialized Program of Research Excellence), National Heart Lung and Blood Institute, National Institute of Environmental Health Sciences Center,......trategies. Says Feinberg, “It could be possible to screen for colon cancer risk by looking at the epigenetic changes in colon cells of healthy people.? ...Down syndrome: It's not just the age factor
...hanisms and therapeutic restoration of a stringent screen holds promise not only for Down Syndrome." ...MIT's molecular sieve advances protein research
...ze of a thumbnail. The sieve makes it possible to screen proteins by specific size and shape.In contrast, the current technique used for separating proteins, gel electrophoresis, is time-consuming and less predictable. Pore sizes in the gels vary, and the process itself is not well understood by scientists...Protein 'fingerprint' in spinal fluid could spot Alzheimer's disease
...Based on their clinical symptoms, we found the new screen to have 93 percent sensitivity to probable cases o...in). "Data gleaned from the use of this 23-protein screen suggests that IVIg may be having a positive impact on underlying disease processes." And while a s...A fisheye view of the deadliest breast cancer
...ggressive of human breast cancers, and to rapidly screen for drugs that might stop IBC, researchers at the University of California, San Diego (UCSD), have come up with an unlikely yet extremely promising ally: a transparent fish suitable for xenografts. More properly, it’s a transgenic zebrafish, a tro...Nano-devices hold promise for early-stage cancer detection
...heter, or woven into fabric. Their function is to screen for, detect, and potentially treat, cancer and other diseases when they are still at a single-cell size in early development stages. They will also detect harmful pathogens in food and water. Engineering researchers at McMaster University will be e...Friendly bacteria in alcoholic milkshake could fight food allergies
...vention of allergies. "In the future, maybe we can screen out the certain components (bacterial strains or bioactive peptides) from kefir and utilize them in medicine," he said. Also in this weeks Chemistry & Industry, UK firm Rigest are looking for backers to develop an air sanitizing system using a...Prototype just-in-time medical device enables untrained bystanders to save lives
...n anesthesia mask, defibrillator pads, and a video screen and speakers that transmit audio and visual cues to tell the user what to do and give him or her feedback about actions taken. The cues were based on American Heart Association protocols. Half the 40 participants used the JITS device and half did n...Caterpillars tell us how bacteria cause disease
...working with other research teams across the UK to screen other harmful bacteria using RVA in an attempt to identify genes which could be possible vaccine targets to prevent disease outbreaks in the future. Professor Julia Goodfellow, BBSRC Chief Executive, said: "This sort of genomics research is cruci...Experimental vaccine protects mice against deadly 1918 flu virus
...s to the H5N1 avian flu virus and could be used to screen for monoclonal antibodies that may be used as an antiviral treatment, according to Dr. Nabel. "This technique would be very useful in defining evolving serotypes of flu viruses like H5N1 to develop immune sera and neutralizing monoclonal antibodies...Professors to develop hand-held pathogen testing device
...tters for human health," Hashsham said. "If we can screen for all pathogens together, we can minimize the threat significantly." Hashsham intends for the portable, hand-held device to be an all-in-one pathogen testing center where DNA amplification and pathogen identification will happen on the same DNA...Gene chip technology shows potential for identifying life-threatening blood infection
... to make it practical to develop a bedside test to screen for signs of infection. He is also exploring whether gene chips can identify the specific type of invading organism in the blood samples. Early findings suggest that the technology detects differences in molecular profiles based on the type of pathog...