Taking Aim With Nanoparticle PEBBLEs
...he David and Goliath story, University of Michigan scientists hope to slay a big killer with pebbles. In this case, the killer is not a fearsome giant, but a dreaded disease: cancer. And the pebbles are not the kind you hurl from slingshots; they're nanoscale polymer beads known as Photonic Explorers for Biomed...UCSD researchers maintain stem cells without contaminated animal feeder layers
...bility to become all tissue types in the body. The scientists knew that a cocktail of various growth factors and chemicals had previously been shown to modulate cellular growth and differentiation in human pancreatic cells. Human embryonic stem cells cultured for several weeks under these conditions showed no c...Scientists develop new color-coded test for protein folding
...s it to function properly. Now Stanford University scientists have developed a simple test that instantly changes color when a protein molecule attached to a gold nanoparticle folds or unfolds. The new technique, which works on the same principle as ordinary pH tests that measure the acidity of water, is descri...Placenta Is A Rich Source Of Blood Stem Cells
...mber of blood stem cells. For more than a decade, scientists have believed that blood stem cells are made only in the embryo itself, within the region of the developing aorta. No role was suspected for the placenta, which has been seen as simply a place for nutrient exchange and waste removal between mother an...Probing The Promise And Perils Of Nanoparticles
...faces to make them neutral instead of charged, the scientists found. And, added Banaszak Holl, "not only does engineering make them less harmful, but it also makes them better at what we want them to do. You don't lose anything; it's all a gain." More recently, Leroueil studied other types of charged nanoparti...Study shows nanoshells ideal as chemical nanosensors
...of the lightinteracts in such a way that it allows scientists to determine theirdetailed chemical makeup. This property, known as Raman scattering, isused by medical researchers, drug designers, chemists and otherscientists to determine what materials are made of. An enormouslimitation in the use of Raman scatt...Researchers find missing genes of ancient organism
Yale scientists report in the journal Nature that the "missing" genes for tRNA in an ancient parasite are made up by splicing together sequences in distant parts of the DNA genome. The research led by Professor Dieter Söll in the Department of Molecular Biophysics ...Same mutation aided evolution in many fish species, Stanford study finds
...ighter, spryer fish. This is among the first times scientists have shown that the same genetic change is responsible for an evolutionary adaptation in disparate populations. "Almost every time the stickleback evolves in fresh water it loses the armor," said David Kingsley, PhD, professor of developmental biolo...Gene Therapy For Parkinson's Disease Moves Forward In Animals
An international team of scientists has used gene therapy in two separate studies to r...es. By inserting corrective genes into the brain, scientists studying small monkeys called marmosets prevented brain damage by producing therapeutic levels of a ...Researchers trace evolution to relatively simple genetic changes
In a stunning example of evolution at work, scientists have now found that changes in a single gene can produce major changes in the skeletal armor of fish living in the wild. The surprising results, announced in the March 25, 2005, issue of journal Science, bring new data to long-standing debates about...Scientists reveal molecular secrets of the malaria parasite
... with implicationsfor malaria vaccine development, scientists have used genomics,proteomics and gene expression ...n, thatmolecular-level data may benefit biomedical scientists who areidentifying new targets for vaccines that would impede the parasiteduring stages when it is p...Octopuses occasionally stroll around on two arms, UC Berkeley biologists report
In a stunning example of evolution at work, scientists have now found that changes in a single gene can produce major changes in the skeletal armor of fish living in the wild. The surprising results, announced in the March 25, 2005, issue of journal Science, bring new data to long-standing debates about...Scientists discover unique microbe in California's largest lake
...small subunit ribosomal RNA gene is widely used by scientists toinfer the relationships among living organisms, in part because it isgenerally assumed that it is faithfully transmitted from parent tooffspring. However, in the case of this new microbe, it appears thatDNA encoding a small portion of the ribosomal...Research Gives Hope For Liver Damage
...val is to receive a liver transplant.The Edinburgh scientists from the University's Centre for InflammationResea...her research into macrophages is set to follow and scientists willexplore the role of these immune-system cells in damage and repair toother organs, including the...New SARS Protein Linked To Important Cell Doorway
...rtant to the SARS virus' ability to cause disease, scientists will already have much of the knowledge they need to develop ways to disable or weaken it. "The key to studying novel viruses used to be the ability to isolate the virus and grow it in a culture," notes lead author Daved Fremont, Ph.D., assistant pr...MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks
... in contemporary molecularbiology research, aiding scientists in analyzing data and in testinghypotheses with simulated outcomes before testing them experimentally.The predictive capabilities of computer simulations can also aidbiologists in viewing cellular activity over a period of time, bytaking advantage of...Jumping gene helps explain immune system's abilities
A team led by Johns Hopkins scientists hasfound the first clear evidence that the process behind the human immunesystem's remarkable ability to recognize and respond to a milliondifferent proteins might have originated from a family of genes whoseonly apparent function is to jump around i...UCSD Discovery Shows How Embryonic Stem Cells Perform 'Quality Control' Inspections
A team led by Johns Hopkins scientists hasfound the first clear evidence that the process behind the human immunesystem's remarkable ability to recognize and respond to a milliondifferent proteins might have originated from a family of genes whoseonly apparent function is to jump around i...Scientists document complex genomic events leading to the birth of new genes
A team of scientists led by Peer Bork, Ph.D., Senior Bioinformatics Scientist at the European Molecular Biology Laboratory, report today in the journal Genome Research that they have identified a new primate-specific gene family that spans about 10% of human chromosome 2...New therapy for HIV/AIDS eliminates needles and excessive toxicity
A team led by Johns Hopkins scientists hasfound the first clear evidence that the process behind the human immunesystem's remarkable ability to recognize and respond to a milliondifferent proteins might have originated from a family of genes whoseonly apparent function is to jump around i...