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Tag: "scar" at biology news

Gene therapy converts dead bone graft to new, living tissue

...normally trigger the body to wrap the "invader" in scar tissue. "That recognition is the key," says Schwarz. "It's at that point that the body actually begins changing the dead, foreign bone splint, into the body's own, whole, living bone." Such a transformation can occur because mammals use their skele...

Artifical cornea lets woman blind 20 years see

...but rather progressive growth of blood vessels and scar tissue throughout an implanted natural cornea, according to researchers. The new cornea eventually becomes as opaque as the original. "The cornea is usually just like a clear window in the eye for people to see through, but sometimes the cornea beco...

Stem Cell Research Shows Potential for Replacing Tissue Damaged in Heart Attacks

...s die, and the damaged heart muscle is replaced by scar tissue that isn’t able to contract and help the heart beat. This problem is one of the biggest clinical issues faced by heart patients in the United States today,?says Dr. Lough. In looking at ways to use ES cells, the research team had to consider ...

Nano-bumps could help repair clogged blood vessels

...g to the scaffolding and prompting the creation of scar tissue, which can build up inside blood vessels an...to these stents without creating as much dangerous scar tissue." The researchers tested discs of titanium containing surface bumps about as wide as 100 nan...

Master gene controls healing of skin in fruit flies and mammals

...t fly mutants. She suspected that the lesions were scar tissue resulting from the failure of the body surface barrier to develop properly. Confirming her suspicions, the mutant embryos turned out to be much more permeable to a dye than normal embryos. The group also showed that the genes active in the mu...

Stem cell treatment improves mobility after spinal cord injury

...pace surrounding neuron cells had been filled with scar tissue. In the presence of a scar, myelin could not grow. These studies indicate the importance of myelin loss in spinal cord injury, and illustrate one approach to treating myelin loss. Keirstead and his colleagues are currently working on other ap...

New method shows it is possible to grow bone for grafts within a patient's body

...or concern was that the bioreactor would fill with scar tissue instead of bone, but that didn't happen. Instead, it filled with bone that is indistinguishable from the original bone. The scientists intend to proceed with the large animal studies and clinical trials necessary to determine if the procedure...

Modified collagen could yield important medical applications

...and a treatment to block the formation of unwanted scar tissue. In addition, tissue engineers may be able ...rmally attracts cells to close up a wound and form scar tissue. But this property is not always desirable; a clot can be dangerous inside a blood vessel or ...

Unusual antibiotics show promise against deadly 'superbugs'

...and a treatment to block the formation of unwanted scar tissue. In addition, tissue engineers may be able ...rmally attracts cells to close up a wound and form scar tissue. But this property is not always desirable; a clot can be dangerous inside a blood vessel or ...

Woods Hole Research Center plans controlled burn in Amazon rainforest

...res around the world. The fire and subsequent fire scar could both be easily seen, however, using the Hyperion EO-1 sensor data. Our hope is that these studies will allow us to better monitor forest fire from space and, eventually, to determine which forests are most susceptible to fire during the dry sea...

Researchers identify genes associated with lung transplant rejection

...tly available online. In obliterative bronchitis, scar tissue forms in breathing passages of the transpla...ucts associated with inflammation and formation of scar tissue in breathing passages. Using a customized version of a conventional laboratory technique, the...

Muscle repair: Making a good system better, faster; implications for aging, disease

...fficient repair of many tissues and for minimizing scar formation. Koh noted the following specific areas of interest: * PAI-1 levels appear to increase with aging, and may explain, in part, the loss of repair capacity as we age. Koh plans to see whether manipulating PAI-1 levels can restore muscle ...

OHSU researchers discover potential mechanism to repair brain damage linked to Multiple Sclerosis

...ral palsy (CP). Our early findings have shown that scar tissue in the brains of premature infants who die during intensive care also produces HA. We believe the HA may also prevent the production of myelin-producing cells and be related to the motor impairment seen in CP. My hope is that this work will be...

Molecular Partners Required For Appropriate Neuronal Gene Repression

...ral palsy (CP). Our early findings have shown that scar tissue in the brains of premature infants who die during intensive care also produces HA. We believe the HA may also prevent the production of myelin-producing cells and be related to the motor impairment seen in CP. My hope is that this work will be...

Cells from amniotic fluid used to tissue-engineer a new trachea

...r implanting stents (in the hope that tissue would scar around the stents and form a tube), but with limited success. "These are all makeshift solutions, and they're fraught with complications infection, narrowing of the trachea, reoperation," Fauza says. Working with sheep, considered a good model for ...

Depression model leaves mice with molecular scar

...ors, allowing them to accumulate. "The molecular scar induced by chronic stress in the hippocampus, and perhaps elsewhere in the brain, can't be easily reversed," said Nestler. "To really cure depression, we probably need to find new treatments that can remove the silencer molecules." ...

New drug could reduce tissue damage after heart attack

... limiting both early mortality and the size of the scar left in the heart. "Provided adequate support is available, it should be possible to undertake clinical trials of CRP inhibition within a couple of years. If the treatment proves safe and effective, we also aim to investigate its effectiveness in s...

World first research to speed up cure for ear infections

...nd scarring and be potentially applied to clinical scar treatments. Professor Marcus Atlas, Director of LEHI, said that Dr Ghassemifar's work in LEHI's Tissue Engineering Laboratory is potentially ground breaking. "Chronic otitis media is a major problem throughout the world and particularly affects the...

Spinal cord bridge bypasses injury to restore mobility

...icing defenses put up a roadblock in the form of a scar to prevent further injury, but it stops all neural...wth inhibitory molecules from forming in the small scar that forms at the exit ramp of the bridge, where it is inserted into the spinal cord on the other si...

Researcher studies, treats military with 'silent disease'

... to 20 percent had cirrhosis, a condition in which scar tissue replaces healthy tissue, blocking the flow of blood through the organ and preventing it from working as it should. Cirrhosis is the twelfth leading cause of death by disease, killing about 26,000 people each year, according to The National Dig...

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